KAP1 recruitment of the 7SK snRNP complex to promoters enables transcription elongation by RNA polymerase II RP McNamara, JE Reeder, EA McMillan, CW Bacon, JL McCann, I D’Orso Molecular cell 61 (1), 39-53, 2016 | 141 | 2016 |
Transcription factors mediate the enzymatic disassembly of promoter-bound 7SK snRNP to locally recruit P-TEFb for transcription elongation RP McNamara, JL McCann, SA Gudipaty, I D’Orso Cell reports 5 (5), 1256-1268, 2013 | 96 | 2013 |
Nef secretion into extracellular vesicles or exosomes is conserved across human and simian immunodeficiency viruses RP McNamara, LM Costantini, TA Myers, B Schouest, NJ Maness, ... MBio 9 (1), 10.1128/mbio. 02344-17, 2018 | 93 | 2018 |
Large-scale, cross-flow based isolation of highly pure and endocytosis-competent extracellular vesicles RP McNamara, CP Caro-Vegas, LM Costantini, JT Landis, JD Griffith, ... Journal of extracellular vesicles 7 (1), 1541396, 2018 | 86 | 2018 |
HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells JE Reeder, YT Kwak, RP McNamara, CV Forst, I D'Orso Elife 4, e08955, 2015 | 66 | 2015 |
Modern techniques for the isolation of extracellular vesicles and viruses RP McNamara, DP Dittmer Journal of Neuroimmune Pharmacology 15, 459-472, 2020 | 60 | 2020 |
Extracellular vesicles from Kaposi Sarcoma-associated herpesvirus lymphoma induce long-term endothelial cell reprogramming RP McNamara, PE Chugh, A Bailey, LM Costantini, Z Ma, R Bigi, ... PLoS pathogens 15 (2), e1007536, 2019 | 52 | 2019 |
PPM1G binds 7SK RNA and Hexim1 to block P-TEFb assembly into the 7SK snRNP and sustain transcription elongation SA Gudipaty, RP McNamara, EL Morton, I D'Orso Molecular and cellular biology 35 (22), 3810-3828, 2015 | 51 | 2015 |
Fc-γR-dependent antibody effector functions are required for vaccine-mediated protection against antigen-shifted variants of SARS-CoV-2 SR Mackin, P Desai, BM Whitener, CE Karl, M Liu, RS Baric, DK Edwards, ... Nature microbiology 8 (4), 569-580, 2023 | 46 | 2023 |
High-density amplicon sequencing identifies community spread and ongoing evolution of SARS-CoV-2 in the Southern United States RP McNamara, C Caro-Vegas, JT Landis, R Moorad, LJ Pluta, AB Eason, ... Cell reports 33 (5), 2020 | 45 | 2020 |
Transcription elongation control by the 7SK snRNP complex: Releasing the pause RP McNamara, CW Bacon, I D'Orso Cell Cycle 15 (16), 2115-2123, 2016 | 41 | 2016 |
Imaging of surface microdomains on individual extracellular vesicles in 3‐D RP McNamara, Y Zhou, AB Eason, JT Landis, MG Chambers, S Willcox, ... Journal of Extracellular Vesicles 11 (3), e12191, 2022 | 36 | 2022 |
Extracellular vesicles in virus infection and pathogenesis RP McNamara, DP Dittmer Current opinion in virology 44, 129-138, 2020 | 31 | 2020 |
Enhancing the immunogenicity of lipid-nanoparticle mRNA vaccines by adjuvanting the ionizable lipid and the mRNA B Li, AY Jiang, I Raji, C Atyeo, TM Raimondo, AGR Gordon, LH Rhym, ... Nature Biomedical Engineering, 1-18, 2023 | 24 | 2023 |
Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination LE Adams, SR Leist, KH Dinnon, A West, KL Gully, EJ Anderson, ... Cell Reports 42 (4), 2023 | 19 | 2023 |
Efficacy of mRNA-1273 and Novavax ancestral or BA. 1 spike booster vaccines against SARS-CoV-2 BA. 5 infection in nonhuman primates NK Routhu, SD Stampfer, L Lai, A Akhtar, X Tong, D Yuan, TM Chicz, ... Science Immunology 8 (88), eadg7015, 2023 | 17 | 2023 |
Nonlytic cellular release of hepatitis A virus requires dual capsid recruitment of the ESCRT-associated Bro1 domain proteins HD-PTP and ALIX T Shirasaki, H Feng, HME Duyvesteyn, WG Fusco, KL McKnight, L Xie, ... PLoS Pathogens 18 (8), e1010543, 2022 | 11 | 2022 |
Purification methods and the presence of RNA in virus particles and extracellular vesicles Y Zhou, RP McNamara, DP Dittmer Viruses 12 (9), 917, 2020 | 11 | 2020 |
Genome-wide analysis of KAP1, the 7SK snRNP complex, and RNA polymerase II RP McNamara, C Guzman, JE Reeder, I D'Orso Genomics Data 7, 250-255, 2016 | 11 | 2016 |
Large‐scale heparin‐based bind‐and‐elute chromatography identifies two biologically distinct populations of extracellular vesicles Y Zhou, R Yuan, AS Cone, KW Shifflett, GF Arias, A Peng, MG Chambers, ... Journal of extracellular vesicles 12 (6), 12327, 2023 | 9 | 2023 |