Ste5 tethers multiple protein kinases in the MAP kinase cascade required for mating in S. cerevisiae KY Chol, B Satterberg, DM Lyons, EA Elion Cell 78 (3), 499-512, 1994 | 707 | 1994 |
Crystal structure of LacI member, PurR, bound to DNA: minor groove binding by α helices MA Schumacher, KY Choi, H Zalkin, RG Brennan Science 266 (5186), 763-770, 1994 | 502 | 1994 |
5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation YH Cho, EJ Ro, JS Yoon, T Mizutani, DW Kang, JC Park, T Il Kim, ... Nature communications 11 (1), 5321, 2020 | 245 | 2020 |
Both ERK and Wnt/β-catenin pathways are involved in Wnt3a-induced proliferation MS Yun, SE Kim, SH Jeon, JS Lee, KY Choi Journal of cell science 118 (2), 313-322, 2005 | 241 | 2005 |
Role of oncogenic K-Ras in cancer stem cell activation by aberrant Wnt/β-catenin signaling BS Moon, WJ Jeong, J Park, TI Kim, DS Min, KY Choi Journal of the National Cancer Institute 106 (2), djt373, 2014 | 199 | 2014 |
Interaction between Wnt/β-catenin and RAS-ERK pathways and an anti-cancer strategy via degradations of β-catenin and RAS by targeting the Wnt/β-catenin pathway WJ Jeong, EJ Ro, KY Choi NPJ Precision oncology 2 (1), 5, 2018 | 196 | 2018 |
Ras stabilization through aberrant activation of Wnt/β-catenin signaling promotes intestinal tumorigenesis WJ Jeong, J Yoon, JC Park, SH Lee, SH Lee, S Kaduwal, H Kim, JB Yoon, ... Science signaling 5 (219), ra30-ra30, 2012 | 188 | 2012 |
Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway GA Jung, JY Yoon, BS Moon, DH Yang, HY Kim, SH Lee, V Bryja, ... BMC cell biology 9, 1-12, 2008 | 147 | 2008 |
Molecular Cloning and Characterization of aDrosophila p38 Mitogen-activated Protein Kinase SJ Han, KY Choi, PT Brey, WJ Lee Journal of Biological Chemistry 273 (1), 369-374, 1998 | 128 | 1998 |
Mechanism of corepressor-mediated specific DNA binding by the purine repressor MA Schumacher, KY Choi, F Lu, H Zalkin, RG Brennan Cell 83 (1), 147-155, 1995 | 124 | 1995 |
Proto-oncogene FBI-1 represses transcription of p21CIP1 by inhibition of transcription activation by p53 and Sp1 WI Choi, BN Jeon, CO Yun, PH Kim, SE Kim, KY Choi, SH Kim, MW Hur Journal of Biological Chemistry 284 (19), 12633-12644, 2009 | 122 | 2009 |
The SH3-domain protein Bem1 coordinates mitogen-activated protein kinase cascade activation with cell cycle control in Saccharomyces cerevisiae DM Lyons, SK Mahanty, KY Choi, M Manandhar, EA Elion Molecular and cellular biology, 1996 | 122 | 1996 |
Peroxisomal proliferator-activated receptor-γ upregulates glucokinase gene expression in β-cells H Kim, JY Cha, SY Kim, J Kim, KJ Roh, JK Seong, NT Lee, KY Choi, ... Diabetes 51 (3), 676-685, 2002 | 118 | 2002 |
Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells SH Lee, J Yoon, SH Shin, M Zahoor, HJ Kim, PJ Park, WS Park, DS Min, ... PLoS One 7 (4), e34152, 2012 | 116 | 2012 |
H-Ras is degraded by Wnt/β-catenin signaling via β-TrCP-mediated polyubiquitylation SE Kim, JY Yoon, WJ Jeong, SH Jeon, Y Park, JB Yoon, YN Park, H Kim, ... Journal of cell science 122 (6), 842-848, 2009 | 108 | 2009 |
MEK1/2 Inhibitors AS703026 and AZD6244 May Be Potential Therapies for KRAS Mutated Colorectal Cancer That Is Resistant to EGFR Monoclonal Antibody … J Yoon, KH Koo, KY Choi Cancer research 71 (2), 445-453, 2011 | 103 | 2011 |
Nonstructural 5A protein activates β-catenin signaling cascades: implication of hepatitis C virus-induced liver pathogenesis CY Park, SH Choi, SM Kang, JI Kang, BY Ahn, H Kim, G Jung, KY Choi, ... Journal of hepatology 51 (5), 853-864, 2009 | 101 | 2009 |
Transcriptional activity of Sp1 is regulated by molecular interactions between the zinc finger DNA binding domain and the inhibitory domain with corepressors, and this … JA Lee, DC Suh, JE Kang, MH Kim, H Park, MN Lee, JM Kim, BN Jeon, ... Journal of Biological Chemistry 280 (30), 28061-28071, 2005 | 96 | 2005 |
Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation PH Cha, YH Cho, SK Lee, JH Lee, WJ Jeong, BS Moon, JH Yun, JS Yang, ... Nature chemical biology 12 (8), 593-600, 2016 | 95 | 2016 |
The PI3 kinase-Akt pathway mediates Wnt3a-induced proliferation SE Kim, WJ Lee, KY Choi Cellular signalling 19 (3), 511-518, 2007 | 94 | 2007 |