Synthesis of the C (18)− C (34) Fragment of Amphidinolide C and the C (18)− C (29) Fragment of Amphidinolide F S Roy, CD Spilling Organic Letters, 2010 | 77 | 2010 |
Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis X Wu, G Gardashova, L Lan, S Han, C Zhong, RT Marquez, L Wei, ... Communications biology 3 (1), 193, 2020 | 76 | 2020 |
HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells R Muralidharan, M Mehta, R Ahmed, S Roy, L Xu, J Aubé, A Chen, ... Scientific reports 7 (1), 9694, 2017 | 75 | 2017 |
A task specific basic ionic liquid,[bmIm] OH-promoted efficient, green and one-pot synthesis of tetrahydrobenzo [b] pyran derivatives BC Ranu, S Banerjee, S Roy CSIR, 2008 | 72 | 2008 |
Development of (E)-2-((1,4-Dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-Amidinophenylbenzamides as Potent Inhibitors of Venezuelan … CE Schroeder, T Yao, J Sotsky, RA Smith, S Roy, YK Chu, H Guo, ... Journal of Medicinal Chemistry 57 (20), 8608-8621, 2014 | 50 | 2014 |
Discovery, synthesis, and optimization of diarylisoxazole‐3‐carboxamides as potent inhibitors of the mitochondrial permeability transition pore S Roy, J Šileikytė, M Schiavone, B Neuenswander, F Argenton, J Aubé, ... ChemMedChem 10 (10), 1655-1671, 2015 | 49 | 2015 |
Human antigen R as a therapeutic target in pathological cardiac hypertrophy LC Green, SR Anthony, S Slone, L Lanzillotta, ML Nieman, X Wu, ... JCI insight 4 (4), 2019 | 48 | 2019 |
N‐Phenylbenzamides as Potent Inhibitors of the Mitochondrial Permeability Transition Pore S Roy, J Šileikytė, B Neuenswander, MP Hedrick, TDY Chung, J Aubé, ... ChemMedChem 11 (3), 283-288, 2016 | 43 | 2016 |
Optimization Rules for SARS-CoV-2 Mpro Antivirals: Ensemble Docking and Exploration of the Coronavirus Protease Active Site SV Stoddard, SD Stoddard, BK Oelkers, K Fitts, K Whalum, K Whalum, ... Viruses 12 (9), 942, 2020 | 42 | 2020 |
The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells L Allegri, F Baldan, S Roy, J Aubé, D Russo, S Filetti, G Damante Scientific reports 9 (1), 7374, 2019 | 41 | 2019 |
Regioselective synthesis of 4-fluoro-1, 5-disubstituted-1, 2, 3-triazoles from synthetic surrogates of α-fluoroalkynes S Jana, S Adhikari, MR Cox, S Roy Chemical communications 56 (12), 1871-1874, 2020 | 33 | 2020 |
An Expeditious Total Synthesis of Both Diastereoisomeric Lipid Dihydroxytetrahydrofurans from Notheia anomala S Roy, CD Spilling Organic letters 14 (9), 2230-2233, 2012 | 31 | 2012 |
HuR reduces radiation-induced DNA damage by enhancing expression of ARID1A D Andrade, M Mehta, J Griffith, S Oh, J Corbin, A Babu, S De, A Chen, ... Cancers 11 (12), 2014, 2019 | 25 | 2019 |
ML336: Development of quinazolinone-based inhibitors against Venezuelan equine encephalitis virus (VEEV) D Chung, CE Schroeder, J Sotsky, T Yao, S Roy, RA Smith, NA Tower, ... Probe Reports from the NIH Molecular Libraries Program [Internet], 2013 | 17 | 2013 |
Small molecules targeting the mitochondrial permeability transition J Sileikyte, S Roy, P Porubsky, B Neuenswander, J Wang, M Hedrick, ... Probe Reports from the NIH Molecular Libraries Program [Internet], 2015 | 14 | 2015 |
Hexafluoroisopropanol and Acetyl Chloride Promoted Catalytic Hydroarylation with Phenols S Roy, HF Motiwala, KM Koshlap, J Aubé European Journal of Organic Chemistry 2018 (3), 306-315, 2018 | 11 | 2018 |
Small molecules targeting the RNA-binding protein HuR inhibit tumor growth in xenografts X Wu, R Ramesh, J Wang, Y Zheng, AM Armaly, L Wei, M Xing, S Roy, ... Journal of medicinal chemistry 66 (3), 2032-2053, 2023 | 8 | 2023 |
Identification of potential non-nucleoside MraY inhibitors for tuberculosis chemotherapy using structure-based virtual screening P Pandey, S Chatterjee, T Berida, RJ Doerksen, S Roy Journal of Biomolecular Structure and Dynamics 40 (11), 4832-4849, 2022 | 6 | 2022 |
Identification of antimalarial inhibitors using late-stage gametocytes in a phenotypic live/dead assay TP Spicer, DL Gardiner, FJ Schoenen, S Roy, PR Griffin, P Chase, ... SLAS DISCOVERY: Advancing Life Sciences R&D 24 (1), 38-46, 2019 | 6 | 2019 |
A Practical and Scalable Synthesis of (S)-and (R)-1-(Dimethoxyphosphoryl) allyl Methyl Carbonates S Roy, N Sutivisedsak, BC Hamper, AM Lyss, CD Spilling Synthesis, 3669-3672, 2015 | 3 | 2015 |