Integrated genomic analyses of ovarian carcinoma Cancer Genome Atlas Research Network Nature 474 (7353), 609, 2011 | 6909 | 2011 |
A variant of the HTRA1 gene increases susceptibility to age-related macular degeneration Z Yang, NJ Camp, H Sun, Z Tong, D Gibbs, DJ Cameron, H Chen, Y Zhao, ... Science 314 (5801), 992-993, 2006 | 964 | 2006 |
Mutant prominin 1 found in patients with macular degeneration disrupts photoreceptor disk morphogenesis in mice Z Yang, Y Chen, C Lillo, J Chien, Z Yu, M Michaelides, M Klein, ... The Journal of clinical investigation 118 (8), 2908-2916, 2008 | 299 | 2008 |
Loss of HSulf-1 up-regulates heparin-binding growth factor signaling in cancer J Lai, J Chien, J Staub, R Avula, EL Greene, TA Matthews, DI Smith, ... Journal of Biological Chemistry 278 (25), 23107-23117, 2003 | 296 | 2003 |
A candidate tumor suppressor HtrA1 is downregulated in ovarian cancer J Chien, J Staub, SI Hu, MR Erickson-Johnson, FJ Couch, DI Smith, ... Oncogene 23 (8), 1636-1644, 2004 | 206 | 2004 |
Metformin intake is associated with better survival in ovarian cancer: A case‐control study S Kumar, A Meuter, P Thapa, C Langstraat, S Giri, J Chien, R Rattan, ... Cancer 119 (3), 555-562, 2013 | 196 | 2013 |
Serine protease HtrA1 modulates chemotherapy-induced cytotoxicity J Chien, G Aletti, A Baldi, V Catalano, P Muretto, GL Keeney, KR Kalli, ... The Journal of clinical investigation 116 (7), 1994-2004, 2006 | 187 | 2006 |
hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling J Lai, JR Chien, DR Moser, JK Staub, I Aderca, DP Montoya, TA Matthews, ... Gastroenterology 126 (1), 231-248, 2004 | 185 | 2004 |
APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma B Leonard, SN Hart, MB Burns, MA Carpenter, NA Temiz, A Rathore, ... Cancer research 73 (24), 7222-7231, 2013 | 181 | 2013 |
HSulf-1 inhibits angiogenesis and tumorigenesis in vivo K Narita, J Staub, J Chien, K Meyer, M Bauer, A Friedl, S Ramakrishnan, ... Cancer research 66 (12), 6025-6032, 2006 | 179 | 2006 |
Network-based survival analysis reveals subnetwork signatures for predicting outcomes of ovarian cancer treatment W Zhang, T Ota, V Shridhar, J Chien, B Wu, R Kuang PLoS computational biology 9 (3), e1002975, 2013 | 176 | 2013 |
HSulf-1 modulates HGF-mediated tumor cell invasion and signaling in head and neck squamous carcinoma JP Lai, J Chien, SE Strome, J Staub, DP Montoya, EL Greene, DI Smith, ... Oncogene 23 (7), 1439-1447, 2004 | 161 | 2004 |
Clinical Characteristics of Ovarian Cancer Classified by BRCA1, BRCA2 and RAD51C Status JM Cunningham, MS Cicek, NB Larson, J Davila, C Wang, MC Larson, ... Scientific reports 4 (1), 4026, 2014 | 158 | 2014 |
HtrA serine proteases as potential therapeutic targets in cancer J Chien, M Campioni, V Shridhar, A Baldi Current cancer drug targets 9 (4), 451-468, 2009 | 156 | 2009 |
Serine protease HtrA1 associates with microtubules and inhibits cell migration J Chien, T Ota, G Aletti, R Shridhar, M Boccellino, L Quagliuolo, A Baldi, ... Molecular and cellular biology 29 (15), 4177-4187, 2009 | 143 | 2009 |
Epigenetic silencing of HSulf-1 in ovarian cancer: implications in chemoresistance J Staub, J Chien, Y Pan, X Qian, K Narita, G Aletti, M Scheerer, ... Oncogene 26 (34), 4969-4978, 2007 | 141 | 2007 |
Identification of underexpressed genes in early-and late-stage primary ovarian tumors by suppression subtraction hybridization V Shridhar, A Sen, J Chien, J Staub, R Avula, S Kovats, J Lee, J Lillie, ... Cancer research 62 (1), 262-270, 2002 | 132 | 2002 |
Bevacizumab may differentially improve ovarian cancer outcome in patients with proliferative and mesenchymal molecular subtypes S Kommoss, B Winterhoff, AL Oberg, GE Konecny, C Wang, SM Riska, ... Clinical Cancer Research 23 (14), 3794-3801, 2017 | 126 | 2017 |
Platinum-sensitive recurrence in ovarian cancer: the role of tumor microenvironment J Chien, R Kuang, C Landen, V Shridhar Frontiers in oncology 3, 251, 2013 | 120 | 2013 |
Ovarian cancer prevention, screening, and early detection: report from the 11th biennial ovarian cancer research symposium J Chien, EM Poole International Journal of Gynecologic Cancer 27 (S5), 2017 | 117 | 2017 |