| Ion permeation in K+ channels occurs by direct Coulomb knock-on DA Köpfer, C Song, T Gruene, GM Sheldrick, U Zachariae, BL de Groot Science 346 (6207), 352-355, 2014 | 318 | 2014 |
| Computational electrophysiology: the molecular dynamics of ion channel permeation and selectivity in atomistic detail C Kutzner, H Grubmüller, BL De Groot, U Zachariae Biophysical journal 101 (4), 809-817, 2011 | 244 | 2011 |
| Direct knock-on of desolvated ions governs strict ion selectivity in K+ channels W Kopec, DA Köpfer, ON Vickery, AS Bondarenko, TLC Jansen, ... Nature chemistry 10 (8), 813-820, 2018 | 187 | 2018 |
| Structure of the MacAB–TolC ABC-type tripartite multidrug efflux pump AWP Fitzpatrick, S Llabrés, A Neuberger, JN Blaza, X Bai, U Okada, ... Nature microbiology 2 (7), 1-8, 2017 | 174 | 2017 |
| Crystal structure and functional mechanism of a human antimicrobial membrane channel C Song, C Weichbrodt, ES Salnikov, M Dynowski, BO Forsberg, ... Proceedings of the National Academy of Sciences 110 (12), 4586-4591, 2013 | 155 | 2013 |
| Mechanisms of anion conduction by coupled glutamate transporters JP Machtens, D Kortzak, C Lansche, A Leinenweber, P Kilian, ... Cell 160 (3), 542-553, 2015 | 141 | 2015 |
| β-Barrel mobility underlies closure of the voltage-dependent anion channel U Zachariae, R Schneider, R Briones, Z Gattin, JP Demers, K Giller, ... Structure 20 (9), 1540-1549, 2012 | 128 | 2012 |
| Functional dynamics in the voltage-dependent anion channel S Villinger, R Briones, K Giller, U Zachariae, A Lange, BL de Groot, ... Proceedings of the National Academy of Sciences 107 (52), 22546-22551, 2010 | 122 | 2010 |
| Position of transmembrane helix 6 determines receptor G protein coupling specificity AS Rose, M Elgeti, U Zachariae, H Grubmüller, KP Hofmann, ... Journal of the American Chemical Society 136 (32), 11244-11247, 2014 | 117 | 2014 |
| GPCRmd uncovers the dynamics of the 3D-GPCRome I Rodríguez-Espigares, M Torrens-Fontanals, JKS Tiemann, ... Nature Methods 17 (8), 777-787, 2020 | 116 | 2020 |
| Molecular determinants for nuclear import of influenza A PB2 by importin α isoforms 3 and 7 RA Pumroy, S Ke, DJ Hart, U Zachariae, G Cingolani Structure 23 (2), 374-384, 2015 | 111 | 2015 |
| Quantitative structural analysis of importin-β flexibility: paradigm for solenoid protein structures JK Forwood, A Lange, U Zachariae, M Marfori, C Preast, H Grubmüller, ... Structure 18 (9), 1171-1183, 2010 | 111 | 2010 |
| Structural basis for cooperativity of CRM1 export complex formation T Monecke, D Haselbach, B Voß, A Russek, P Neumann, E Thomson, ... Proceedings of the National Academy of Sciences 110 (3), 960-965, 2013 | 99 | 2013 |
| An unusual hydrophobic core confers extreme flexibility to HEAT repeat proteins C Kappel, U Zachariae, N Dölker, H Grubmüller Biophysical journal 99 (5), 1596-1603, 2010 | 86 | 2010 |
| Intracellular transfer of Na+ in an active-state G-protein-coupled receptor ON Vickery, CA Carvalheda, SA Zaidi, AV Pisliakov, V Katritch, ... Structure 26 (1), 171-180. e2, 2018 | 81 | 2018 |
| Interfacial self-assembly of a bacterial hydrophobin KM Bromley, RJ Morris, L Hobley, G Brandani, RMC Gillespie, ... Proceedings of the National Academy of Sciences 112 (17), 5419-5424, 2015 | 78 | 2015 |
| Insights into the function of ion channels by computational electrophysiology simulations C Kutzner, DA Köpfer, JP Machtens, BL De Groot, C Song, U Zachariae Biochimica et Biophysica Acta (BBA)-Biomembranes 1858 (7), 1741-1752, 2016 | 76 | 2016 |
| Toward a consensus model of the HERG potassium channel A Stary, SJ Wacker, L Boukharta, U Zachariae, Y Karimi‐Nejad, J Åqvist, ... ChemMedChem 5 (3), 455-467, 2010 | 74 | 2010 |
| Importin-β: structural and dynamic determinants of a molecular spring U Zachariae, H Grubmüller Structure 16 (6), 906-915, 2008 | 73 | 2008 |
| Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers U Zachariae, F Giordanetto, AG Leach Journal of medicinal chemistry 52 (14), 4266-4276, 2009 | 65 | 2009 |
