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Matthew Carter Childers
Matthew Carter Childers
University of Washington Department of Bioengineering
在 uw.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Insights from molecular dynamics simulations for computational protein design
MC Childers, V Daggett
Molecular systems design & engineering 2 (1), 9-33, 2017
2262017
α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer’s disease
D Shea, CC Hsu, TM Bi, N Paranjapye, MC Childers, J Cochran, ...
Proceedings of the National Academy of Sciences 116 (18), 8895-8900, 2019
1562019
Validating molecular dynamics simulations against experimental observables in light of underlying conformational ensembles
MC Childers, V Daggett
The Journal of Physical Chemistry B 122 (26), 6673-6689, 2018
932018
Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin
JD Powers, CC Yuan, KJ McCabe, JD Murray, MC Childers, GV Flint, ...
Proceedings of the National Academy of Sciences 116 (23), 11502-11507, 2019
412019
Structural OFF/ON transitions of myosin in relaxed porcine myocardium predict calcium-activated force
W Ma, TS McMillen, MC Childers, H Gong, M Regnier, T Irving
Proceedings of the National Academy of Sciences 120 (5), e2207615120, 2023
272023
Myosin dynamics during relaxation in mouse soleus muscle and modulation by 2′‐deoxy‐ATP
W Ma, M Childers, J Murray, F Moussavi‐Harami, H Gong, R Weiss, ...
The Journal of physiology 598 (22), 5165-5182, 2020
272020
The effect of chirality and steric hindrance on intrinsic backbone conformational propensities: tools for protein design
MC Childers, CL Towse, V Daggett
Protein Engineering, Design and Selection 29 (7), 271-280, 2016
262016
Edge strand dissociation and conformational changes in transthyretin under amyloidogenic conditions
MC Childers, V Daggett
Biophysical Journal 119 (10), 1995-2009, 2020
152020
Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts
M Landim-Vieira, MC Childers, AL Wacker, MR Garcia, H He, R Singh, ...
Elife 11, e74919, 2022
142022
Drivers of α-sheet formation in transthyretin under amyloidogenic conditions
MC Childers, V Daggett
Biochemistry 58 (44), 4408-4423, 2019
142019
Modulation of post-powerstroke dynamics in myosin II by 2′-deoxy-ADP
MC Childers, M Geeves, V Daggett, M Regnier
Archives of biochemistry and biophysics 699, 108733, 2021
112021
Molecular dynamics-derived rotamer libraries for d-amino acids within homochiral and heterochiral polypeptides
MC Childers, CL Towse, V Daggett
Protein Engineering, Design and Selection 31 (6), 191-204, 2018
92018
Conserved patterns and interactions in the unfolding transition state across SH3 domain structural homologues
C Demakis, MC Childers, V Daggett
Protein Science 30 (2), 391-407, 2021
62021
Molecular dynamics methods for antibody design
MC Childers, V Daggett
Computer-Aided Antibody Design, 109-124, 2022
52022
Variants in ACTC1 underlie distal arthrogryposis accompanied by congenital heart defects
JX Chong, MC Childers, CT Marvin, AJ Marcello, H Gonorazky, ...
Human Genetics and Genomics Advances 4 (3), 2023
42023
Insights from molecular dynamics simulations for computational protein design. Molecular Systems Design & Engineering, 2 (1), 9–33
MC Childers, V Daggett
42017
Atomistic simulations of sarcomere proteins
MC Childers, M Regnier
Familial Cardiomyopathies: Methods and Protocols, 27-41, 2023
22023
Conformational sampling of CMT-2D associated GlyRS mutations
MC Childers, M Regnier, M Bothwell, AST Smith
Brain multiphysics 3, 100054, 2022
22022
Myosin’s powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin
MJ Rynkiewicz, MC Childers, OE Karpicheva, M Regnier, MA Geeves, ...
Journal of General Physiology 156 (5), e202413538, 2024
12024
Myosin’s powerstroke transitions define atomic scale movement of cardiac thin filament tropomyosin
W Lehman, MC Childers, M Regnier, MA Geeves, MJ Rynkiewicz
Biophysical Journal 123 (3), 16a-17a, 2024
12024
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