Illuminating insights into protein-protein interactions using bioluminescence resonance energy transfer (BRET) KDG Pfleger, KA Eidne Nature methods 3 (3), 165-174, 2006 | 677 | 2006 |
Building a new conceptual framework for receptor heteromers S Ferré, R Baler, M Bouvier, MG Caron, LA Devi, T Durroux, K Fuxe, ... Nature chemical biology 5 (3), 131-134, 2009 | 477 | 2009 |
G protein–coupled receptor heteromers I Gomes, MA Ayoub, W Fujita, WC Jaeger, KDG Pfleger, LA Devi Annual review of pharmacology and toxicology 56 (1), 403-425, 2016 | 277 | 2016 |
Bioluminescence resonance energy transfer (BRET) for the real-time detection of protein-protein interactions KDG Pfleger, RM Seeber, KA Eidne Nature protocols 1 (1), 337-345, 2006 | 267 | 2006 |
Application of BRET to monitor ligand binding to GPCRs LA Stoddart, EKM Johnstone, AJ Wheal, J Goulding, MB Robers, ... Nature methods 12 (7), 661-663, 2015 | 254 | 2015 |
Monitoring the formation of dynamic G-protein-coupled receptor–protein complexes in living cells KDG Pfleger, KA Eidne Biochemical Journal 385 (3), 625-637, 2005 | 211 | 2005 |
NanoBRET: the bright future of proximity-based assays NC Dale, EKM Johnstone, CW White, KDG Pfleger Frontiers in bioengineering and biotechnology 7, 56, 2019 | 152 | 2019 |
Extended bioluminescence resonance energy transfer (eBRET) for monitoring prolonged protein–protein interactions in live cells KDG Pfleger, JR Dromey, MB Dalrymple, EML Lim, WG Thomas, ... Cellular signalling 18 (10), 1664-1670, 2006 | 129 | 2006 |
Fluorescence‐and bioluminescence‐based approaches to study GPCR ligand binding LA Stoddart, CW White, K Nguyen, SJ Hill, KDG Pfleger British journal of pharmacology 173 (20), 3028-3037, 2016 | 128 | 2016 |
G-protein coupled receptor oligomerization in neuroendocrine pathways KM Kroeger, KDG Pfleger, KA Eidne Frontiers in Neuroendocrinology 24 (4), 254-278, 2003 | 120 | 2003 |
Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer C Duffy, A Sorolla, E Wang, E Golden, E Woodward, K Davern, D Ho, ... NPJ precision oncology 4 (1), 24, 2020 | 116 | 2020 |
Recent advances in bioluminescence resonance energy transfer technologies to study GPCR heteromerization MA Ayoub, KDG Pfleger Current opinion in pharmacology 10 (1), 44-52, 2010 | 116 | 2010 |
Demonstration of improvements to the bioluminescence resonance energy transfer (BRET) technology for the monitoring of G protein–coupled receptors in live cells M Kocan, HB See, RM Seeber, KA Eidne, KDG Pfleger SLAS Discovery 13 (9), 888-898, 2008 | 116 | 2008 |
G protein-coupled receptor dimers: functional consequences, disease states and drug targets MB Dalrymple, KDG Pfleger, KA Eidne Pharmacology & therapeutics 118 (3), 359-371, 2008 | 108 | 2008 |
Identification and profiling of CXCR3–CXCR4 chemokine receptor heteromer complexes AO Watts, MMH Van Lipzig, WC Jaeger, RM Seeber, M Van Zwam, ... British journal of pharmacology 168 (7), 1662-1674, 2013 | 81 | 2013 |
Heteromerization of angiotensin receptors changes trafficking and arrestin recruitment profiles ER Porrello, KDG Pfleger, RM Seeber, H Qian, C Oro, F Abogadie, ... Cellular signalling 23 (11), 1767-1776, 2011 | 80 | 2011 |
Transactivation of RAGE mediates angiotensin-induced inflammation and atherogenesis RJ Pickering, C Tikellis, CJ Rosado, D Tsorotes, A Dimitropoulos, M Smith, ... The Journal of clinical investigation 129 (1), 406-421, 2019 | 78 | 2019 |
Deleterious GRM1 mutations in schizophrenia MA Ayoub, D Angelicheva, D Vile, D Chandler, B Morar, JA Cavanaugh, ... PLoS One 7 (3), e32849, 2012 | 77 | 2012 |
Differential association modes of the thrombin receptor PAR1 with Gαil, Gα12, and β‐arrestin 1 MA Ayoub, E Trinquet, KDG Pfleger, JP Pin The FASEB Journal 24 (9), 3522-3535, 2010 | 74 | 2010 |
New technologies: bioluminescence resonance energy transfer (BRET) for the detection of real time interactions involving G-protein coupled receptors KDG Pfleger, KA Eidne Pituitary 6, 141-151, 2003 | 74 | 2003 |