Butelase 1 is an Asx-specific ligase enabling peptide macrocyclization and synthesis GKT Nguyen, S Wang, Y Qiu, X Hemu, Y Lian, JP Tam Nature chemical biology 10 (9), 732-738, 2014 | 448 | 2014 |
Orally active peptidic bradykinin B1 receptor antagonists engineered from a cyclotide scaffold for inflammatory pain treatment CTT Wong, DK Rowlands, CH Wong, TWC Lo, GKT Nguyen, HY Li, ... Angewandte Chemie-International Edition 51 (23), 5620, 2012 | 262 | 2012 |
Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family GKT Nguyen, S Zhang, NTK Nguyen, PQT Nguyen, MS Chiu, A Hardjojo, ... Journal of Biological Chemistry 286 (27), 24275-24287, 2011 | 217 | 2011 |
Engineering a catalytically efficient recombinant protein ligase R Yang, YH Wong, GKT Nguyen, JP Tam, J Lescar, B Wu Journal of the American Chemical Society 139 (15), 5351-5358, 2017 | 192 | 2017 |
Butelase 1: a versatile ligase for peptide and protein macrocyclization GKT Nguyen, A Kam, S Loo, AE Jansson, LX Pan, JP Tam Journal of the American Chemical Society 137 (49), 15398-15401, 2015 | 183 | 2015 |
Butelase-mediated cyclization and ligation of peptides and proteins GKT Nguyen, Y Qiu, Y Cao, X Hemu, CF Liu, JP Tam Nature protocols 11 (10), 1977-1988, 2016 | 137 | 2016 |
Discovery of linear cyclotides in monocot plant Panicum laxum of Poaceae family provides new insights into evolution and distribution of cyclotides in plants GKT Nguyen, Y Lian, EWH Pang, PQT Nguyen, TD Tran, JP Tam Journal of Biological Chemistry 288 (5), 3370-3380, 2013 | 127 | 2013 |
Site‐specific N‐terminal labeling of peptides and proteins using butelase 1 and thiodepsipeptide GKT Nguyen, Y Cao, W Wang, CF Liu, JP Tam Angewandte Chemie 127 (52), 15920-15924, 2015 | 126 | 2015 |
Total synthesis of circular bacteriocins by butelase 1 X Hemu, Y Qiu, GKT Nguyen, JP Tam Journal of the American Chemical Society 138 (22), 6968-6971, 2016 | 112 | 2016 |
Butelase‐Mediated Macrocyclization of d‐Amino‐Acid‐Containing Peptides GKT Nguyen, X Hemu, JP Quek, JP Tam Angewandte Chemie 128 (41), 12994-12998, 2016 | 101 | 2016 |
Butelase-mediated synthesis of protein thioesters and its application for tandem chemoenzymatic ligation KT Giang Chemical Communications 51 (97), 17289-17292, 2015 | 97 | 2015 |
Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionine oxidation on bioactivities GKT Nguyen, WH Lim, PQT Nguyen, JP Tam Journal of Biological Chemistry 287 (21), 17598-17607, 2012 | 93 | 2012 |
Enzymatic engineering of live bacterial cell surfaces using butelase 1 X Bi, J Yin, GKT Nguyen, C Rao, NBA Halim, X Hemu, JP Tam, CF Liu Angewandte Chemie International Edition 56 (27), 7822-7825, 2017 | 92 | 2017 |
Discovery of a linear cyclotide from the bracelet subfamily and its disulfide mapping by top-down mass spectrometry GKT Nguyen, S Zhang, W Wang, CTT Wong, NTK Nguyen, JP Tam Journal of Biological Chemistry 286 (52), 44833-44844, 2011 | 80 | 2011 |
Immunostimulating and Gram‐negative‐specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea) KNT Nguyen, GKT Nguyen, PQT Nguyen, KH Ang, PC Dedon, JP Tam The FEBS journal 283 (11), 2067-2090, 2016 | 72 | 2016 |
A high-throughput peptidomic strategy to decipher the molecular diversity of cyclic cysteine-rich peptides A Serra, X Hemu, GKT Nguyen, NTK Nguyen, SK Sze, JP Tam Scientific Reports 6 (1), 23005, 2016 | 58 | 2016 |
Butelase-mediated ligation as an efficient bioconjugation method for the synthesis of peptide dendrimers Y Cao, GKT Nguyen, S Chuah, JP Tam, CF Liu Bioconjugate chemistry 27 (11), 2592-2596, 2016 | 54 | 2016 |
Antiviral cystine knot α-amylase inhibitors from Alstonia scholaris PQT Nguyen, JSG Ooi, NTK Nguyen, S Wang, M Huang, DX Liu, JP Tam Journal of Biological Chemistry 290 (52), 31138-31150, 2015 | 50 | 2015 |
Allotides: Proline-Rich Cystine Knot α-Amylase Inhibitors from Allamanda cathartica PQT Nguyen, TT Luu, Y Bai, GKT Nguyen, K Pervushin, JP Tam Journal of natural products 78 (4), 695-704, 2015 | 42 | 2015 |
Identification and Characterization of Roseltide, a Knottin-type Neutrophil Elastase Inhibitor Derived from Hibiscus sabdariffa S Loo, A Kam, T Xiao, GKT Nguyen, CF Liu, JP Tam Scientific reports 6 (1), 39401, 2016 | 37 | 2016 |