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Landscape of somatic mutations and clonal evolution in mantle cell lymphoma S Beà, R Valdés-Mas, A Navarro, I Salaverria, D Martín-Garcia, P Jares, ... Proceedings of the National Academy of Sciences 110 (45), 18250-18255, 2013 | 601 | 2013 |
The proteasome inhibitor bortezomib induces apoptosis in mantle-cell lymphoma through generation of ROS and Noxa activation independent of p53 status P Pérez-Galán, G Roué, N Villamor, E Montserrat, E Campo, D Colomer Blood 107 (1), 257-264, 2006 | 546 | 2006 |
The BH3-mimetic GX15-070 synergizes with bortezomib in mantle cell lymphoma by enhancing Noxa-mediated activation of Bak P Pérez-Galán, G Roué, N Villamor, E Campo, D Colomer Blood 109 (10), 4441-4449, 2007 | 239 | 2007 |
SOX11 regulates PAX5 expression and blocks terminal B-cell differentiation in aggressive mantle cell lymphoma MC Vegliante, J Palomero, P Pérez-Galán, G Roué, G Castellano, ... Blood, The Journal of the American Society of Hematology 121 (12), 2175-2185, 2013 | 218 | 2013 |
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78 G Roue, P Perez-Galan, A Mozos, M Lopez-Guerra, S Xargay-Torrent, ... Blood, The Journal of the American Society of Hematology 117 (4), 1270-1279, 2011 | 130 | 2011 |
The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma E Sanchez-Tillo, L Fanlo, L Siles, S Montes-Moreno, A Moros, ... Cell Death & Differentiation 21 (2), 247-257, 2014 | 127 | 2014 |
In vitro and In vivo Selective Antitumor Activity of Edelfosine against Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Involving Lipid Rafts F Mollinedo, J de la Iglesia-Vicente, C Gajate, AEH de Mendoza, ... Clinical Cancer Research 16 (7), 2046-2054, 2010 | 123 | 2010 |
Drp1 mediates caspase-independent type III cell death in normal and leukemic cells M Bras, VJ Yuste, G Roué, S Barbier, P Sancho, C Virely, M Rubio, ... Molecular and cellular biology 27 (20), 7073-7088, 2007 | 118 | 2007 |
Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma A Moros, V Rodriguez, I Saborit-Villarroya, A Montraveta, P Balsas, ... Leukemia 28 (10), 2049-2059, 2014 | 114 | 2014 |
BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells P Perez-Galan, G Roue, M Lopez-Guerra, M Nguyen, N Villamor, ... Leukemia 22 (9), 1712-1720, 2008 | 105 | 2008 |
Lipid raft-mediated Akt signaling as a therapeutic target in mantle cell lymphoma M Reis-Sobreiro, G Roué, A Moros, C Gajate, J De La Iglesia-Vicente, ... Blood cancer journal 3 (5), e118-e118, 2013 | 103 | 2013 |
Bendamustine is effective in p53-deficient B-cell neoplasms and requires oxidative stress and caspase-independent signaling G Roue, M López-Guerra, P Milpied, P Perez-Galan, N Villamor, ... Clinical cancer research 14 (21), 6907-6915, 2008 | 102 | 2008 |
Selective inhibition of IκB kinase sensitizes mantle cell lymphoma B cells to TRAIL by decreasing cellular FLIP level G Roue, P Perez-Galan, M Lopez-Guerra, N Villamor, E Campo, ... The Journal of Immunology 178 (3), 1923-1930, 2007 | 96 | 2007 |
Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters S Xargay-Torrent, M López-Guerra, I Saborit-Villarroya, L Rosich, ... Clinical Cancer Research 17 (12), 3956-3968, 2011 | 92 | 2011 |
The BET bromodomain inhibitor CPI203 overcomes resistance to ABT-199 (venetoclax) by downregulation of BFL-1/A1 in in vitro and in vivo models of MYC+/BCL2+ double hit lymphoma A Esteve-Arenys, JG Valero, A Chamorro-Jorganes, D Gonzalez, ... Oncogene 37 (14), 1830-1844, 2018 | 87 | 2018 |
The expression of the endoplasmic reticulum stress sensor BiP/GRP78 predicts response to chemotherapy and determines the efficacy of proteasome inhibitors in diffuse large b … A Mozos, G Roué, A López-Guillermo, P Jares, E Campo, D Colomer, ... The American journal of pathology 179 (5), 2601-2610, 2011 | 78 | 2011 |
Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma L Rosich, S Xargay-Torrent, M López-Guerra, E Campo, D Colomer, ... Clinical cancer research 18 (19), 5278-5289, 2012 | 75 | 2012 |
Plasmablastic transformation of low-grade B-cell lymphomas: report on 6 cases D Martinez, A Valera, NS Perez, LFS Villegas, B Gonzalez-Farre, C Sole, ... The American journal of surgical pathology 37 (2), 272-281, 2013 | 71 | 2013 |
Cyclin D1 mediates resistance to apoptosis through upregulation of molecular chaperones and consequent redistribution of cell death regulators G Roue, V Pichereau, H Lincet, D Colomer, B Sola Oncogene 27 (36), 4909-4920, 2008 | 69 | 2008 |