Clinical advances of hypoxia-activated prodrugs in combination with radiation therapy IN Mistry, M Thomas, EDD Calder, SJ Conway, EM Hammond International Journal of Radiation Oncology* Biology* Physics 98 (5), 1183-1196, 2017 | 151 | 2017 |
Preparation of anti-Vicinal Amino Alcohols: Asymmetric Synthesis of d-erythro-Sphinganine, (+)-Spisulosine, and d-ribo-Phytosphingosine EDD Calder, AM Zaed, A Sutherland The Journal of Organic Chemistry 78 (14), 7223-7233, 2013 | 67 | 2013 |
Stereodivergent organocatalytic intramolecular michael addition/lactonization for the asymmetric synthesis of substituted dihydrobenzofurans and tetrahydrofurans D Belmessieri, A De La Houpliere, EDD Calder, JE Taylor, AD Smith Chemistry–A European Journal 20 (31), 9762-9769, 2014 | 57 | 2014 |
Intermolecular Aryl C− H Amination through Sequential Iron and Copper Catalysis MAB Mostafa, EDD Calder, DT Racys, A Sutherland Chemistry–A European Journal 23 (5), 1044-1047, 2017 | 43 | 2017 |
Preparation of Amino-Substituted Indenes and 1,4-Dihydronaphthalenes Using a One-Pot Multireaction Approach: Total Synthesis of Oxybenzo[c]phenanthridine … EDD Calder, FI McGonagle, AH Harkiss, GA McGonagle, A Sutherland The Journal of Organic Chemistry 79 (16), 7633-7648, 2014 | 34 | 2014 |
One-pot multi-reaction processes: Synthesis of natural products and drug-like scaffolds EDD Calder, MW Grafton, A Sutherland Synlett 25 (08), 1068-1080, 2014 | 34 | 2014 |
One-Pot Synthesis of 5-Amino-2, 5-Dihydro-1-Benzoxepines: Access to Pharmacologically Active Heterocyclic Scaffolds EDD Calder, SAI Sharif, FI McGonagle, A Sutherland The Journal of organic chemistry 80, 4683, 2015 | 33 | 2015 |
Synthesis of 5-Amino-2,5-dihydro-1H-benzo[b]azepines Using a One-Pot Multibond Forming Process SAI Sharif, EDD Calder, FG Delolo, A Sutherland The Journal of Organic Chemistry 81 (15), 6697-6706, 2016 | 31 | 2016 |
Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor A Skwarska, EDD Calder, D Sneddon, H Bolland, ML Odyniec, IN Mistry, ... Cell chemical biology 28 (9), 1258-1270. e13, 2021 | 28 | 2021 |
Hypoxia-activated pro-drugs of the KDAC inhibitor vorinostat (SAHA) EDD Calder, A Skwarska, D Sneddon, LK Folkes, IN Mistry, SJ Conway, ... Tetrahedron 76 (21), 131170, 2020 | 21 | 2020 |
Enantioselective Synthesis of 3-Methyleneindan-1-ols via a One-Pot Allylboration–Heck Reaction of 2-Bromobenzaldehydes EDD Calder, A Sutherland Organic letters 17 (10), 2514-2517, 2015 | 19 | 2015 |
Low temperature capture of pseudorotaxanes NI Hassan, V Del Amo, E Calder, D Philp Organic Letters 13 (3), 458-461, 2011 | 18 | 2011 |
Synthesis of Allylic Amide Functionalized 2H-Chromenes and Coumarins Using a One-Pot Overman Rearrangement and Gold(I)-Catalyzed Hydroarylation SAI Sharif, EDD Calder, AH Harkiss, M Maduro, A Sutherland The Journal of Organic Chemistry 81 (20), 9810-9819, 2016 | 15 | 2016 |
Strategies to expand peptide functionality through hybridisation with a small molecule component Y Wu, J Williams, EDD Calder, LJ Walport RSC Chemical Biology 2 (1), 151-165, 2021 | 12 | 2021 |
Characterization of HSP90 isoforms in transformed bovine leukocytes infected with Theileria annulata JH Kinnaird, M Singh, V Gillan, W Weir, EDD Calder, I Hostettler, U Tatu, ... Cellular microbiology 19 (3), e12669, 2017 | 10 | 2017 |
One-Pot Asymmetric Synthesis of Alkylidene 1-Alkylindan-1-ols Using Brønsted Acid and Palladium Catalysis RJ Faggyas, EDD Calder, C Wilson, A Sutherland The Journal of Organic Chemistry 82 (21), 11585-11593, 2017 | 7 | 2017 |
Zap‐Pano: a Photocaged Prodrug of the KDAC Inhibitor Panobinostat KS Troelsen, EDD Calder, A Skwarska, D Sneddon, EM Hammond, ... ChemMedChem 16 (24), 3691-3700, 2021 | 6 | 2021 |
Fluorescent Amino Acid Initiated de novo Cyclic Peptides for the Label‐Free Assessment of Cell Permeability** Y Wu, MT Bertran, J Rowley, EDD Calder, D Joshi, LJ Walport ChemMedChem 16 (20), 3185-3188, 2021 | 3 | 2021 |
Discovering Covalent Cyclic Peptide Inhibitors of Peptidyl Arginine Deiminase 4 (PADI4) Using mRNA-Display with a Genetically Encoded Electrophilic Warhead I Mathiesen, E Calder, S Kunzelmann, L Walport | | 2024 |
The design, synthesis, and evaluation of hypoxia-activated prodrugs of the KDAC inhibitor panobinostat E Calder, A Skwarska, D Sneddon, L Folkes, IN Mistry, EM Hammond, ... | | 2020 |