Synthesis and investigation of anti-inflammatory activity and gastric ulcerogenicity of novel nitric oxide-donating pyrazoline derivatives ME Shoman, M Abdel-Aziz, OM Aly, HH Farag, MA Morsy European journal of medicinal chemistry 44 (7), 3068-3076, 2009 | 108 | 2009 |
Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties ME Shoman, JF DuMond, TS Isbell, JH Crawford, A Brandon, J Honovar, ... Journal of medicinal chemistry 54 (4), 1059-1070, 2011 | 81 | 2011 |
Molecular hybrids: A five-year survey on structures of multiple targeted hybrids of protein kinase inhibitors for cancer therapy OM Soltan, ME Shoman, SA Abdel-Aziz, A Narumi, H Konno, ... European Journal of Medicinal Chemistry 225, 113768, 2021 | 70 | 2021 |
New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity SH Abbas, AA Abd El-Hafeez, ME Shoman, MM Montano, HA Hassan Bioorganic chemistry 82, 360-377, 2019 | 57 | 2019 |
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs GEDA Abuo-Rahma, MFA Mohamed, TS Ibrahim, ME Shoman, E Samir, ... RSC advances 10 (45), 26895-26916, 2020 | 54 | 2020 |
New 1, 3, 4-oxadiazole/oxime hybrids: Design, synthesis, anti-inflammatory, COX inhibitory activities and ulcerogenic liability HS Abd-Ellah, M Abdel-Aziz, ME Shoman, EAM Beshr, TS Kaoud, ... Bioorganic Chemistry 74, 15-29, 2017 | 53 | 2017 |
Novel 1, 3, 4-oxadiazole/oxime hybrids: Synthesis, docking studies and investigation of anti-inflammatory, ulcerogenic liability and analgesic activities HS Abd-Ellah, M Abdel-Aziz, ME Shoman, EAM Beshr, TS Kaoud, ... Bioorganic chemistry 69, 48-63, 2016 | 48 | 2016 |
Spirohydantoins and 1, 2, 4-triazole-3-carboxamide derivatives as inhibitors of histone deacetylase: Design, synthesis, and biological evaluation AMA Aboeldahab, EAM Beshr, ME Shoman, SM Rabea, OM Aly European journal of medicinal chemistry 146, 79-92, 2018 | 39 | 2018 |
Design and synthesis of new coumarin–chalcone/NO hybrids of potential biological activity HA El-Sherief, GEDA Abuo-Rahma, ME Shoman, EA Beshr, ... Medicinal Chemistry Research 26, 3077-3090, 2017 | 30 | 2017 |
Nitroxide derivatives of non‐steroidal anti‐inflammatory drugs exert anti‐inflammatory and superoxide dismutase scavenging properties in A459 cells W Flores‐Santana, T Moody, W Chen, MJ Gorczynski, ME Shoman, ... British journal of pharmacology 165 (4b), 1058-1067, 2012 | 28 | 2012 |
Nitroxyl (HNO): a possible strategy for fighting cancer M E Shoman, O M Aly Current Topics in Medicinal Chemistry 16 (22), 2464-2470, 2016 | 27 | 2016 |
Thiazolidine-2, 4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial, MRSA and topoisomerase inhibitory activities HA Aziz, AMM El-Saghier, M Badr, GEDA Abuo-Rahma, ME Shoman Molecular Diversity 26 (3), 1743-1759, 2022 | 22 | 2022 |
Direct and nitroxyl (HNO)-mediated reactions of acyloxy nitroso compounds with the thiol-containing proteins glyceraldehyde 3-phosphate dehydrogenase and alkyl hydroperoxide … S Mitroka, ME Shoman, JF DuMond, L Bellavia, OM Aly, M Abdel-Aziz, ... Journal of medicinal chemistry 56 (17), 6583-6592, 2013 | 22 | 2013 |
[Retracted] Nitroxyl (HNO): A Reduced Form of Nitric Oxide with Distinct Chemical, Pharmacological, and Therapeutic Properties ME Shoman, OM Aly Oxidative Medicine and Cellular Longevity 2016 (1), 4867124, 2016 | 21 | 2016 |
Ring expansions of acyloxy nitroso compounds MB Hadimani, R Mukherjee, R Banerjee, ME Shoman, OM Aly, SB King Tetrahedron letters 56 (43), 5870-5873, 2015 | 18 | 2015 |
Vanillin-based indolin-2-one derivative bearing a pyridyl moiety as a promising anti-breast cancer agent via anti-estrogenic activity O Bender, I Celik, R Dogan, A Atalay, ME Shoman, TFS Ali, EAM Beshr, ... ACS omega 8 (7), 6968-6981, 2023 | 17 | 2023 |
Discovery of oxindole‐based FLT3 inhibitors as a promising therapeutic lead for acute myeloid leukemia carrying the oncogenic ITD mutation O Bender, ME Shoman, TFS Ali, R Dogan, I Celik, A Mollica, MIA Hamed, ... Archiv der Pharmazie 356 (2), 2200407, 2023 | 16 | 2023 |
New nicotinic acid-based 3, 5-diphenylpyrazoles: Design, synthesis and antihyperlipidemic activity with potential NPC1L1 inhibitory activity ME Shoman, MO Aboelez, MSHA Shaykhon, SA Ahmed, ... Molecular Diversity 25, 673-686, 2021 | 15 | 2021 |
New multi-targeted antiproliferative agents: Design and synthesis of IC261-based oxindoles as potential tubulin, CK1 and EGFR inhibitors MR Fareed, ME Shoman, MIA Hamed, M Badr, HA Bogari, SS Elhady, ... Pharmaceuticals 14 (11), 1114, 2021 | 14 | 2021 |
Phytochemical investigation of Amphilophium paniculatum; an underexplored Bignoniaceae species as a source of SARS-CoV-2 Mpro inhibitory metabolites: Isolation, identification … MN Samy, EZ Attia, ME Shoman, HE Khalil, S Sugimoto, K Matsunami, ... South African Journal of Botany 141, 421-430, 2021 | 12 | 2021 |