Bispecific and split CAR T cells targeting CD13 and TIM3 eradicate acute myeloid leukemia X He, Z Feng, J Ma, S Ling, Y Cao, B Gurung, Y Wu, BW Katona, ... Blood, The Journal of the American Society of Hematology 135 (10), 713-723, 2020 | 159 | 2020 |
USP22 promotes hypoxia-induced hepatocellular carcinoma stemness by a HIF1α/USP22 positive feedback loop upon TP53 inactivation S Ling, Q Shan, Q Zhan, Q Ye, P Liu, S Xu, X He, J Ma, J Xiang, G Jiang, ... Gut 69 (7), 1322-1334, 2020 | 138 | 2020 |
Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome B Gurung, Z Feng, DV Iwamoto, A Thiel, G Jin, CM Fan, JMY Ng, T Curran, ... Cancer research 73 (8), 2650-2658, 2013 | 115 | 2013 |
Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription B Xu, SH Li, R Zheng, SB Gao, LH Ding, ZY Yin, X Lin, ZJ Feng, S Zhang, ... Proceedings of the National Academy of Sciences 110 (43), 17480-17485, 2013 | 73 | 2013 |
Lung cancer cell migration is regulated via repressing growth factor PTN/RPTP β/ζ signaling by menin ZJ Feng, SB Gao, Y Wu, XF Xu, X Hua, GH Jin Oncogene 29 (39), 5416-5426, 2010 | 69 | 2010 |
Suppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin SB Gao, ZJ Feng, B Xu, Y Wu, P Yin, Y Yang, X Hua, GH Jin Oncogene 28 (46), 4095-4104, 2009 | 68 | 2009 |
Epigenetic regulation by the menin pathway Z Feng, J Ma, X Hua Endocrine-related cancer 24 (10), T147, 2017 | 55 | 2017 |
The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma SB Gao, B Xu, LH Ding, QL Zheng, L Zhang, QF Zheng, SH Li, ZJ Feng, ... Journal of hepatology 61 (4), 832-839, 2014 | 52 | 2014 |
Menin directly represses Gli1 expression independent of canonical Hedgehog signaling B Gurung, Z Feng, X Hua Molecular Cancer Research 11 (10), 1215-1222, 2013 | 52 | 2013 |
Interplay between menin and K-Ras in regulating lung adenocarcinoma Y Wu, ZJ Feng, SB Gao, S Matkar, B Xu, HB Duan, X Lin, SH Li, X Hua, ... Journal of Biological Chemistry 287 (47), 40003-40011, 2012 | 52 | 2012 |
Potent suppression of neuroendocrine tumors and gastrointestinal cancers by CDH17CAR T cells without toxicity to normal tissues Z Feng, X He, X Zhang, Y Wu, B Xing, A Knowles, Q Shan, S Miller, ... Nature Cancer 3 (5), 581-594, 2022 | 47 | 2022 |
The trithorax protein partner menin acts in tandem with EZH2 to suppress C/EBPα and differentiation in MLL-AF9 leukemia AT Thiel, Z Feng, DK Pant, LA Chodosh, X Hua Haematologica 98 (6), 918, 2013 | 43 | 2013 |
Menin and Daxx interact to suppress neuroendocrine tumors through epigenetic control of the membrane metallo-endopeptidase Z Feng, L Wang, Y Sun, Z Jiang, J Domsic, C An, B Xing, J Tian, X Liu, ... Cancer research 77 (2), 401-411, 2017 | 42 | 2017 |
Combined menin and EGFR inhibitors synergize to suppress colorectal cancer via EGFR-independent and calcium-mediated repression of SKP2 transcription BW Katona, RA Glynn, KE Paulosky, Z Feng, CI Davis, J Ma, CT Berry, ... Cancer research 79 (9), 2195-2207, 2019 | 24 | 2019 |
Disruption of the menin-MLL interaction triggers menin protein degradation via ubiquitin-proteasome pathway Y Wu, M Doepner, T Hojnacki, Z Feng, BW Katona, X He, J Ma, Y Cao, ... American Journal of Cancer Research 9 (8), 1682, 2019 | 23 | 2019 |
SUMO modification of menin ZJ Feng, B Gurung, GH Jin, XL Yang, XX Hua American Journal of Cancer Research 3 (1), 96, 2013 | 22 | 2013 |
Menin represses malignant phenotypes of melanoma through regulating multiple pathways SB Gao, ZJ Feng, B Xu, Y Chen, HH Zheng, P Yin, X Hua, GH Jin Journal of Cellular and Molecular Medicine 15 (11), 2353-2363, 2011 | 19 | 2011 |
GLP-1 signaling suppresses menin’s transcriptional block by phosphorylation in β cells B Xing, J Ma, Z Jiang, Z Feng, S Ling, K Szigety, W Su, L Zhang, R Jia, ... Journal of Cell Biology 218 (3), 855-870, 2019 | 11 | 2019 |
Islet-specific Prmt5 excision leads to reduced insulin expression and glucose intolerance in mice J Ma, X He, Y Cao, K O’Dwyer, KM Szigety, Y Wu, B Gurung, Z Feng, ... Journal of Endocrinology 244 (1), 41-52, 2020 | 10 | 2020 |
Prolactin-regulated Pbk is involved in pregnancy-induced β-cell proliferation in mice Y Cao, Z Feng, X He, X Zhang, B Xing, Y Wu, T Hojnacki, BW Katona, ... Journal of Endocrinology 252 (2), 107-123, 2022 | 9 | 2022 |