Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1 S Welbourn, SM Dutta, OJ Semmes, K Strebel Journal of virology 87 (21), 11516-11524, 2013 | 175 | 2013 |
Inhibition of human P450 enzymes by multiple constituents of the Ginkgo biloba extract C Gaudineau, R Beckerman, S Welbourn, K Auclair Biochemical and biophysical research communications 318 (4), 1072-1078, 2004 | 171 | 2004 |
Hepatitis C virus NS2/3 processing is required for NS3 stability and viral RNA replication S Welbourn, R Green, I Gamache, S Dandache, V Lohmann, ... Journal of Biological Chemistry 280 (33), 29604-29611, 2005 | 90 | 2005 |
The hepatitis C virus NS2/3 protease S Welbourn, A Pause Current issues in molecular biology 9 (1), 63-70, 2007 | 73 | 2007 |
Low dNTP levels are necessary but may not be sufficient for lentiviral restriction by SAMHD1 S Welbourn, K Strebel Virology 488, 271-277, 2016 | 72 | 2016 |
The subcellular localization of the hepatitis C virus non-structural protein NS2 is regulated by an ion channel-independent function of the p7 protein P Tedbury, S Welbourn, A Pause, B King, S Griffin, M Harris Journal of General Virology 92 (4), 819-830, 2011 | 65 | 2011 |
Identification and characterization of naturally occurring splice variants of SAMHD1 S Welbourn, E Miyagi, TE White, F Diaz-Griffero, K Strebel Retrovirology 9, 1-10, 2012 | 35 | 2012 |
Investigation of a role for lysine residues in non-structural proteins 2 and 2/3 of the hepatitis C virus for their degradation and virus assembly S Welbourn, V Jirasko, V Breton, S Reiss, F Penin, R Bartenschlager, ... Journal of General Virology 90 (5), 1071-1080, 2009 | 28 | 2009 |
The Expression of Functional Vpx during Pathogenic SIVmac Infections of Rhesus Macaques Suppresses SAMHD1 in CD4+ Memory T Cells M Shingai, S Welbourn, JM Brenchley, P Acharya, E Miyagi, RJ Plishka, ... PLoS pathogens 11 (5), e1004928, 2015 | 27 | 2015 |
Novel bisphosphonate inhibitors of the human farnesyl pyrophosphate synthase JW De Schutter, S Zaretsky, S Welbourn, A Pause, YS Tsantrizos Bioorganic & medicinal chemistry letters 20 (19), 5781-5786, 2010 | 24 | 2010 |
Antagonism of BST-2/tetherin is a conserved function of the Env glycoprotein of primary HIV-2 isolates CY Chen, M Shingai, S Welbourn, MA Martin, P Borrego, N Taveira, ... Journal of virology 90 (24), 11062-11074, 2016 | 22 | 2016 |
Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART M Pino, S Pereira Ribeiro, A Pagliuzza, K Ghneim, A Khan, E Ryan, ... PLoS Pathogens 17 (8), e1009825, 2021 | 20 | 2021 |
Fibrocytes differ from macrophages but can be infected with HIV-1 M Hashimoto, H Nasser, F Bhuyan, N Kuse, Y Satou, S Harada, ... The Journal of Immunology 195 (9), 4341-4350, 2015 | 20 | 2015 |
HCV NS2/3 Protease S Welbourn, A Pause Hepatitis C Viruses: Genomes and Molecular Biology, 2006 | 14 | 2006 |
Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication PR Gruenke, R Aneja, S Welbourn, OB Ukah, SG Sarafianos, DH Burke, ... Nucleic Acids Research 50 (3), 1701-1717, 2022 | 12 | 2022 |
Positioning of cysteine residues within the N-terminal portion of the BST-2/Tetherin ectodomain is important for functional dimerization of BST-2 S Welbourn, S Kao, KE Du Pont, AJ Andrew, CE Berndsen, K Strebel Journal of Biological Chemistry 290 (6), 3740-3751, 2015 | 11 | 2015 |
Inhibition of Vif-mediated degradation of APOBEC3G through competitive binding of core-binding factor beta E Miyagi, S Welbourn, S Sukegawa, H Fabryova, S Kao, K Strebel Journal of Virology 94 (7), 10.1128/jvi. 01708-19, 2020 | 7 | 2020 |
Novel Compound Inhibitors of HIV-1NL4-3 Vpu CA Robinson, TD Lyddon, HM Gil, DT Evans, YV Kuzmichev, J Richard, ... Viruses 14 (4), 817, 2022 | 4 | 2022 |
V2 hotspot optimized MVA vaccine expressing stabilized HIV-1 Clade C envelope Gp140 delays acquisition of heterologous Clade C Tier 2 challenges in Mamu-A* 01 negative Rhesus … TM Styles, S Gangadhara, PBJ Reddy, A Sahoo, A Shiferaw, S Welbourn, ... Frontiers in Immunology 13, 914969, 2022 | 3 | 2022 |
A neutralizing antibody target in early HIV-1 infection was recapitulated in rhesus macaques immunized with the transmitted/founder envelope sequence S Welbourn, S Chakraborty, JE Yang, AS Gleinich, S Gangadhara, ... PLoS pathogens 18 (5), e1010488, 2022 | 3 | 2022 |