The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice H Guillou, D Zadravec, PGP Martin, A Jacobsson Progress in lipid research 49 (2), 186-199, 2010 | 907 | 2010 |
Liver PPARα is crucial for whole-body fatty acid homeostasis and is protective against NAFLD A Montagner, A Polizzi, E Fouché, S Ducheix, Y Lippi, F Lasserre, ... Gut 65 (7), 1202-1214, 2016 | 632 | 2016 |
The gut microbiota: a major player in the toxicity of environmental pollutants? SP Claus, H Guillou, S Ellero-Simatos Npj biofilms and microbiomes 2 (1), 1-11, 2016 | 599 | 2016 |
The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans F Benhamed, PD Denechaud, M Lemoine, C Robichon, M Moldes, ... The Journal of clinical investigation 122 (6), 2176-2194, 2012 | 426 | 2012 |
Low doses of bisphenol A induce gene expression related to lipid synthesis and trigger triglyceride accumulation in adult mouse liver A Marmugi, S Ducheix, F Lasserre, A Polizzi, A Paris, N Priymenko, ... Hepatology 55 (2), 395-407, 2012 | 344 | 2012 |
Gβγs and the Ras binding domain of p110γ are both important regulators of PI3Kγ signalling in neutrophils S Suire, AM Condliffe, GJ Ferguson, CD Ellson, H Guillou, K Davidson, ... Nature cell biology 8 (11), 1303-1309, 2006 | 221 | 2006 |
Effects of pesticide mixtures in human and animal models: An update of the recent literature V Rizzati, O Briand, H Guillou, L Gamet-Payrastre Chemico-biological interactions 254, 231-246, 2016 | 212 | 2016 |
Novel aspects of PPARα‐mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study PGP Martin, H Guillou, F Lasserre, S Déjean, A Lan, JM Pascussi, ... Hepatology 45 (3), 767-777, 2007 | 162 | 2007 |
PI3Kβ plays a critical role in neutrophil activation by immune complexes S Kulkarni, C Sitaru, Z Jakus, KE Anderson, G Damoulakis, K Davidson, ... Science signaling 4 (168), ra23-ra23, 2011 | 159 | 2011 |
ELOVL2 controls the level of n-6 28: 5 and 30: 5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice D Zadravec, P Tvrdik, H Guillou, R Haslam, T Kobayashi, JA Napier, ... Journal of lipid research 52 (2), 245-255, 2011 | 156 | 2011 |
The same rat Δ6-desaturase not only acts on 18-but also on 24-carbon fatty acids in very-long-chain polyunsaturated fatty acid biosynthesis S D'andrea, H Guillou, S Jan, D Catheline, JN Thibault, M Bouriel, ... Biochemical Journal 364 (1), 49-55, 2002 | 146 | 2002 |
Metabolic effects of a chronic dietary exposure to a low-dose pesticide cocktail in mice: sexual dimorphism and role of the constitutive androstane receptor C Lukowicz, S Ellero-Simatos, M Régnier, A Polizzi, F Lasserre, ... Environmental health perspectives 126 (6), 067007, 2018 | 140 | 2018 |
White-to-brite conversion in human adipocytes promotes metabolic reprogramming towards fatty acid anabolic and catabolic pathways V Barquissau, D Beuzelin, DF Pisani, GE Beranger, A Mairal, ... Molecular metabolism 5 (5), 352-365, 2016 | 136 | 2016 |
Adverse effects of long-term exposure to bisphenol A during adulthood leading to hyperglycaemia and hypercholesterolemia in mice A Marmugi, F Lasserre, D Beuzelin, S Ducheix, L Huc, A Polizzi, ... Toxicology 325, 133-143, 2014 | 132 | 2014 |
A specific ChREBP and PPARα cross-talk is required for the glucose-mediated FGF21 response A Iroz, A Montagner, F Benhamed, F Levavasseur, A Polizzi, E Anthony, ... Cell reports 21 (2), 403-416, 2017 | 129 | 2017 |
New targets for NAFLD L Parlati, M Régnier, H Guillou, C Postic JHEP Reports 3 (6), 100346, 2021 | 125 | 2021 |
Ablation of the very‐long‐chain fatty acid elongase ELOVL3 in mice leads to constrained lipid storage and resistance to diet‐induced obesity D Zach‐Avec, A Brolinson, RM Fisher, C Carneheim, RI Csikasz, ... The FASEB Journal 24 (11), 4366-4377, 2010 | 123 | 2010 |
Hepatic circadian clock oscillators and nuclear receptors integrate microbiome-derived signals A Montagner, A Korecka, A Polizzi, Y Lippi, Y Blum, C Canlet, ... Scientific reports 6 (1), 20127, 2016 | 116 | 2016 |
Oxidative stress in NAFLD: role of nutrients and food contaminants C Rives, A Fougerat, S Ellero-Simatos, N Loiseau, H Guillou, ... Biomolecules 10 (12), 1702, 2020 | 110 | 2020 |
Peroxisome proliferator-activated receptors and their novel ligands as candidates for the treatment of non-alcoholic fatty liver disease A Fougerat, A Montagner, N Loiseau, H Guillou, W Wahli Cells 9 (7), 1638, 2020 | 102 | 2020 |