Multi-target pharmacology: possibilities and limitations of the “skeleton key approach” from a medicinal chemist perspective A Talevi Frontiers in pharmacology 6, 205, 2015 | 346 | 2015 |
Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics A Talevi, CL Bellera Expert Opinion on Drug Discovery 15 (4), 397-401, 2020 | 238 | 2020 |
New QSPR study for the prediction of aqueous solubility of drug-like compounds PR Duchowicz, A Talevi, LE Bruno-Blanch, EA Castro Bioorganic & medicinal chemistry 16 (17), 7944-7955, 2008 | 120 | 2008 |
Carbamazepine-loaded solid lipid nanoparticles and nanostructured lipid carriers: Physicochemical characterization and in vitro/in vivo evaluation SS Montoto, ML Sbaraglini, A Talevi, M Couyoupetrou, M Di Ianni, ... Colloids and Surfaces B: Biointerfaces 167, 73-81, 2018 | 90 | 2018 |
Automedicación en estudiantes de la Universidad Nacional de la Plata (Argentina) C Castronuovo, F Chiclana, L Giosso, G Pensa, M Prario, V Rebollo, ... Latin American Journal of Pharmacy 26 (6), 937, 2007 | 85 | 2007 |
Discovery of anticonvulsant activity of abietic acid through application of linear discriminant analysis A Talevi, MS Cravero, EA Castro, LE Bruno-Blanch Bioorganic & medicinal chemistry letters 17 (6), 1684-1690, 2007 | 79 | 2007 |
Computer-guided drug repurposing: identification of trypanocidal activity of clofazimine, benidipine and saquinavir CL Bellera, DE Balcazar, MC Vanrell, AF Casassa, PH Palestro, ... European journal of medicinal chemistry 93, 338-348, 2015 | 76 | 2015 |
Drug repositioning: current approaches and their implications in the precision medicine era A Talevi Expert Review of Precision Medicine and Drug Development 3 (1), 49-61, 2018 | 62 | 2018 |
Machine Learning in Drug Discovery and Development Part 1: A Primer A Talevi, JF Morales, G Hather, JT Podichetty, S Kim, PC Bloomingdale, ... CPT: pharmacometrics & systems pharmacology 9 (3), 129-142, 2020 | 57 | 2020 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR A Talevi, M Goodarzi, EV Ortiz, PR Duchowicz, CL Bellera, G Pesce, ... European journal of medicinal chemistry 46 (1), 218-228, 2011 | 56 | 2011 |
Application of computer-aided drug repurposing in the search of new cruzipain inhibitors: discovery of amiodarone and bromocriptine inhibitory effects CL Bellera, DE Balcazar, L Alberca, CA Labriola, A Talevi, C Carrillo Journal of chemical information and modeling 53 (9), 2402-2408, 2013 | 55 | 2013 |
Application of descriptors based on Lipinski’s rules in the QSPR study of aqueous solubilities PR Duchowicz, A Talevi, C Bellera, LE Bruno-Blanch, EA Castro Bioorganic & medicinal chemistry 15 (11), 3711-3719, 2007 | 55 | 2007 |
Hybrid Ofloxacin/eugenol co-loaded solid lipid nanoparticles with enhanced and targetable antimicrobial properties B Rodenak-Kladniew, SS Montoto, ML Sbaraglini, M Di Ianni, ME Ruiz, ... International journal of pharmaceutics 569, 118575, 2019 | 53 | 2019 |
Discovery of novel polyamine analogs with anti-protozoal activity by computer guided drug repositioning LN Alberca, ML Sbaraglini, D Balcazar, L Fraccaroli, C Carrillo, ... Journal of computer-aided molecular design 30, 305-321, 2016 | 50 | 2016 |
Synthesis of 2‐Hydrazolyl‐4‐Thiazolidinones Based on Multicomponent Reactions and Biological Evaluation Against Trypanosoma Cruzi C Pizzo, C Saiz, A Talevi, L Gavernet, P Palestro, C Bellera, LB Blanch, ... Chemical biology & drug design 77 (3), 166-172, 2011 | 50 | 2011 |
Computer-aided drug design: An overview A Talevi Computational drug discovery and design, 1-19, 2018 | 45 | 2018 |
An integrated drug development approach applying topological descriptors A Talevi, C L Bellera, M Di Ianni, P R Duchowicz, L E Bruno-Blanch, ... Current computer-aided drug design 8 (3), 172-181, 2012 | 45 | 2012 |
Strengths and Weaknesses of Docking Simulations in the SARS-CoV-2 Era: the Main Protease (Mpro) Case Study MA Llanos, ME Gantner, S Rodriguez, LN Alberca, CL Bellera, A Talevi, ... Journal of Chemical Information and Modeling 61 (8), 3758-3770, 2021 | 44 | 2021 |
A successful virtual screening application: prediction of anticonvulsant activity in MES test of widely used pharmaceutical and food preservatives methylparaben and propylparaben A Talevi, CL Bellera, EA Castro, LE Bruno-Blanch Journal of Computer-Aided Molecular Design 21 (9), 527-538, 2007 | 44 | 2007 |
Neglected tropical protozoan diseases: drug repositioning as a rational option M Laura Sbaraglini, M Cristina Vanrell, C Leticia Bellera, G Benaim, ... Current topics in medicinal chemistry 16 (19), 2201-2222, 2016 | 43 | 2016 |