Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13157* | 2021 |
HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase DC Goldstone, V Ennis-Adeniran, JJ Hedden, HCT Groom, GI Rice, ... Nature 480 (7377), 379-382, 2011 | 958 | 2011 |
The disulfide bond isomerase DsbC is activated by an immunoglobulin‐fold thiol oxidoreductase: crystal structure of the DsbC–DsbDα complex PW Haebel, D Goldstone, F Katzen, J Beckwith, P Metcalf The EMBO journal, 2002 | 151 | 2002 |
Turning a disulfide isomerase into an oxidase: DsbC mutants that imitate DsbA MW Bader, A Hiniker, J Regeimbal, D Goldstone, PW Haebel, J Riemer, ... The EMBO journal, 2001 | 145 | 2001 |
Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice DC Goldstone, PA Walker, LJ Calder, PJ Coombs, J Kirkpatrick, NJ Ball, ... Proceedings of the National Academy of Sciences 111 (26), 9609-9614, 2014 | 124 | 2014 |
Phospho-dependent regulation of SAMHD1 oligomerisation couples catalysis and restriction LH Arnold, HCT Groom, S Kunzelmann, D Schwefel, SJ Caswell, ... PLoS pathogens 11 (10), e1005194, 2015 | 117 | 2015 |
An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis TM Ryan, J Trewhella, JM Murphy, JR Keown, L Casey, FG Pearce, ... Journal of applied crystallography 51 (1), 97-111, 2018 | 78 | 2018 |
Structural and functional analysis of prehistoric lentiviruses uncovers an ancient molecular interface DC Goldstone, MW Yap, LE Robertson, LF Haire, WR Taylor, ... Cell host & microbe 8 (3), 248-259, 2010 | 78 | 2010 |
Structural and functional characterization of a promiscuous feruloyl esterase (Est1E) from the rumen bacterium Butyrivibrio proteoclasticus DC Goldstone, SG Villas‐Bôas, M Till, WJ Kelly, GT Attwood, VL Arcus Proteins: Structure, Function, and Bioinformatics 78 (6), 1457-1469, 2010 | 75 | 2010 |
Structure of the Rna15 RRM–RNA complex reveals the molecular basis of GU specificity in transcriptional 3′-end processing factors C Pancevac, DC Goldstone, A Ramos, IA Taylor Nucleic acids research 38 (9), 3119-3132, 2010 | 73 | 2010 |
Structure of B-MLV capsid amino-terminal domain reveals key features of viral tropism, gag assembly and core formation GB Mortuza, MP Dodding, DC Goldstone, LF Haire, JP Stoye, IA Taylor Journal of molecular biology 376 (5), 1493-1508, 2008 | 69 | 2008 |
Clarification of the C-35 stereochemistries of dinophysistoxin-1 and dinophysistoxin-2 and its consequences for binding to protein phosphatase K Larsen, D Petersen, AL Wilkins, IA Samdal, M Sandvik, T Rundberget, ... Chemical research in toxicology 20 (6), 868-875, 2007 | 68 | 2007 |
Novel escape mutants suggest an extensive TRIM5α binding site spanning the entire outer surface of the murine leukemia virus capsid protein S Ohkura, DC Goldstone, MW Yap, K Holden-Dye, IA Taylor, JP Stoye PLoS pathogens 7 (3), e1002011, 2011 | 62 | 2011 |
Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl2 Complexes D Truong, MP Sullivan, KKH Tong, TR Steel, A Prause, JH Lovett, ... Inorganic chemistry 59 (5), 3281-3289, 2020 | 58 | 2020 |
Ordered assembly of murine leukemia virus capsid protein on lipid nanotubes directs specific binding by the restriction factor, Fv1 L Hilditch, R Matadeen, DC Goldstone, PB Rosenthal, IA Taylor, JP Stoye Proceedings of the National Academy of Sciences 108 (14), 5771-5776, 2011 | 57 | 2011 |
DsbC activation by the N-terminal domain of DsbD D Goldstone, PW Haebel, F Katzen, MW Bader, JCA Bardwell, J Beckwith, ... Proceedings of the National Academy of Sciences 98 (17), 9551-9556, 2001 | 55 | 2001 |
A helical LC3-interacting region mediates the interaction between the retroviral restriction factor Trim5α and mammalian autophagy-related ATG8 proteins JR Keown, MM Black, A Ferron, M Yap, MJ Barnett, FG Pearce, JP Stoye, ... Journal of Biological Chemistry 293 (47), 18378-18386, 2018 | 52 | 2018 |
Structures of human peroxiredoxin 3 suggest self-chaperoning assembly that maintains catalytic state NA Yewdall, H Venugopal, A Desfosses, V Abrishami, Y Yosaatmadja, ... Structure 24 (7), 1120-1129, 2016 | 52 | 2016 |
Anticancer activity of Ru-and Os (arene) compounds of a maleimide-functionalized bioactive pyridinecarbothioamide ligand M Hanif, S Moon, MP Sullivan, S Movassaghi, M Kubanik, DC Goldstone, ... Journal of Inorganic Biochemistry 165, 100-107, 2016 | 48 | 2016 |
Unexpected arene ligand exchange results in the oxidation of an organoruthenium anticancer agent: the first X-ray structure of a protein–Ru (carbene) adduct MP Sullivan, MK Nieuwoudt, GA Bowmaker, NYS Lam, D Truong, ... Chemical communications 54 (48), 6120-6123, 2018 | 44 | 2018 |