The exosome: a conserved eukaryotic RNA processing complex containing multiple 3′→ 5′ exoribonucleases P Mitchell, E Petfalski, A Shevchenko, M Mann, D Tollervey Cell 91 (4), 457-466, 1997 | 1166 | 1997 |
Functions of the exosome in rRNA, snoRNA and snRNA synthesis C Allmang, J Kufel, G Chanfreau, P Mitchell, E Petfalski, D Tollervey The EMBO journal, 1999 | 755 | 1999 |
The yeast exosome and human PM–Scl are related complexes of 3′→ 5′ exonucleases C Allmang, E Petfalski, A Podtelejnikov, M Mann, D Tollervey, P Mitchell Genes & development 13 (16), 2148-2158, 1999 | 597 | 1999 |
mRNA stability in eukaryotes P Mitchell, D Tollervey Current opinion in genetics & development 10 (2), 193-198, 2000 | 389 | 2000 |
Degradation of ribosomal RNA precursors by the exosome C Allmang, P Mitchell, E Petfalski, D Tollervey Nucleic acids research 28 (8), 1684-1691, 2000 | 312 | 2000 |
An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3′→ 5′ degradation P Mitchell, D Tollervey Molecular cell 11 (5), 1405-1413, 2003 | 293 | 2003 |
mRNA turnover P Mitchell, D Tollervey Current opinion in cell biology 13 (3), 320-325, 2001 | 279 | 2001 |
The 3'end of yeast 5.8 S rRNA is generated by an exonuclease processing mechanism. P Mitchell, E Petfalski, D Tollervey Genes & development 10 (4), 502-513, 1996 | 271 | 1996 |
The POP1 gene encodes a protein component common to the RNase MRP and RNase P ribonucleoproteins. Z Lygerou, P Mitchell, E Petfalski, B Séraphin, D Tollervey Genes & development 8 (12), 1423-1433, 1994 | 245 | 1994 |
Rrp47p is an exosome-associated protein required for the 3′ processing of stable RNAs P Mitchell, E Petfalski, R Houalla, A Podtelejnikov, M Mann, D Tollervey Molecular and cellular biology 23 (19), 6982-6992, 2003 | 193 | 2003 |
Musing on the structural organization of the exosome complex P Mitchell, D Tollervey Nature structural biology 7 (10), 843-846, 2000 | 181 | 2000 |
Clustering of modified nucleotides at the functional center of bacterial ribosomal RNA R Brimacombe, P Mitchell, M Osswald, K Stade, D Bochkariov The FASEB journal 7 (1), 161-167, 1993 | 168 | 1993 |
Identification of intermolecular RNA cross-links at the subunit interface of the Escherichia coli ribosome P Mitchell, M Osswald, R Brimacombe Biochemistry 31 (11), 3004-3011, 1992 | 133 | 1992 |
The exosome‐binding factors Rrp6 and Rrp47 form a composite surface for recruiting the Mtr4 helicase B Schuch, M Feigenbutz, DL Makino, S Falk, C Basquin, P Mitchell, ... The EMBO journal 33 (23), 2829-2846, 2014 | 129 | 2014 |
The decoding region of 16S RNA; a cross‐linking study of the ribosomal A, P and E sites using tRNA derivatized at position 32 in the anticodon loop. T Döring, P Mitchell, M Osswald, D Bochkariov, R Brimacombe The EMBO journal 13 (11), 2677-2685, 1994 | 120 | 1994 |
The PMC2NT domain of the catalytic exosome subunit Rrp6p provides the interface for binding with its cofactor Rrp47p, a nucleic acid-binding protein JA Stead, JL Costello, MJ Livingstone, P Mitchell Nucleic acids research 35 (16), 5556-5567, 2007 | 103 | 2007 |
Selective isolation and detailed analysis of intra-RNA cross-links induced in the large ribosomal subunit of E. coli: a model for the tertiary structure of the tRNA binding … P Mitchell, M Osswald, D Schueler, R Brimacombe Nucleic acids research 18 (15), 4325-4333, 1990 | 95 | 1990 |
Methylation sites in Escherichia coli ribosomal RNA: Localization and identification of four new sites of methylation in 23 S rRNA JE Smith, BS Cooperman, P Mitchell Biochemistry 31 (44), 10825-10834, 1992 | 81 | 1992 |
How are tRNAs and mRNA arranged in the ribosome? An attempt to correlate the stereochemistry of the tRNA-mRNA interaction with constraints imposed by the ribosomal topography V Lim, Č Venclovas, A Spirin, R Brimacombe, P Mitchell, F Müller Nucleic acids research 20 (11), 2627-2637, 1992 | 73 | 1992 |
Rrp6, rrp47 and cofactors of the nuclear exosome JS Butler, P Mitchell Adv. Exp. Med. Biol 702, 91-104, 2010 | 69 | 2010 |