| The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids AJ Brown, SM Goldsworthy, AA Barnes, MM Eilert, L Tcheang, D Daniels, ... Journal of Biological Chemistry 278 (13), 11312-11319, 2003 | 2491 | 2003 |
| Heterodimerization is required for the formation of a functional GABAB receptor JH White, A Wise, MJ Main, A Green, NJ Fraser, GH Disney, AA Barnes, ... Nature 396 (6712), 679-682, 1998 | 1501 | 1998 |
| International Union of Pharmacology. XXXIII. Mammalian γ-aminobutyric acidB receptors: structure and function NG Bowery, B Bettler, W Froestl, JP Gallagher, F Marshall, M Raiteri, ... Pharmacological reviews 54 (2), 247-264, 2002 | 817 | 2002 |
| Molecular identification of high and low affinity receptors for nicotinic acid A Wise, SM Foord, NJ Fraser, AA Barnes, N Elshourbagy, M Eilert, ... Journal of Biological Chemistry 278 (11), 9869-9874, 2003 | 652 | 2003 |
| Structure of the adenosine A2A receptor in complex with ZM241385 and the xanthines XAC and caffeine AS Doré, N Robertson, JC Errey, I Ng, K Hollenstein, B Tehan, E Hurrell, ... Structure 19 (9), 1283-1293, 2011 | 639 | 2011 |
| Structure of class B GPCR corticotropin-releasing factor receptor 1 K Hollenstein, J Kean, A Bortolato, RKY Cheng, AS Doré, A Jazayeri, ... Nature 499 (7459), 438-443, 2013 | 504 | 2013 |
| Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain AS Doré, K Okrasa, JC Patel, M Serrano-Vega, K Bennett, RM Cooke, ... Nature 511 (7511), 557-562, 2014 | 466 | 2014 |
| Generic GPCR residue numbers–aligning topology maps while minding the gaps V Isberg, C De Graaf, A Bortolato, V Cherezov, V Katritch, FH Marshall, ... Trends in pharmacological sciences 36 (1), 22-31, 2015 | 461 | 2015 |
| GABAB receptors–the first 7TM heterodimers FH Marshall, KA Jones, K Kaupmann, B Bettler Trends in pharmacological sciences 20 (10), 396-399, 1999 | 455 | 1999 |
| Discovery of 1,2,4-Triazine Derivatives as Adenosine A2A Antagonists using Structure Based Drug Design M Congreve, SP Andrews, AS Doré, K Hollenstein, E Hurrell, ... Journal of medicinal chemistry 55 (5), 1898-1903, 2012 | 369 | 2012 |
| CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain N Clayton, FH Marshall, C Bountra, CT O'shaughnessy Pain 96 (3), 253-260, 2002 | 327 | 2002 |
| Insights into the structure of class B GPCRs K Hollenstein, C de Graaf, A Bortolato, MW Wang, FH Marshall, ... Trends in pharmacological sciences 35 (1), 12-22, 2014 | 267 | 2014 |
| Progress in structure based drug design for G protein-coupled receptors M Congreve, CJ Langmead, JS Mason, FH Marshall Journal of medicinal chemistry 54 (13), 4283-4311, 2011 | 262 | 2011 |
| Structural insight into allosteric modulation of protease-activated receptor 2 RKY Cheng, C Fiez-Vandal, O Schlenker, K Edman, B Aggeler, DG Brown, ... Nature 545 (7652), 112-115, 2017 | 250 | 2017 |
| A bioluminescent assay for agonist activity at potentially any G-protein-coupled receptor J Stables, A Green, F Marshall, N Fraser, E Knight, M Sautel, G Milligan, ... Analytical biochemistry 252 (1), 115-126, 1997 | 242 | 1997 |
| Intracellular allosteric antagonism of the CCR9 receptor C Oswald, M Rappas, J Kean, AS Doré, JC Errey, K Bennett, F Deflorian, ... Nature 540 (7633), 462-465, 2016 | 240 | 2016 |
| The GABAB receptor interacts directly with the related transcription factors CREB2 and ATFx JH White, RAJ McIllhinney, A Wise, F Ciruela, WY Chan, PC Emson, ... Proceedings of the National Academy of Sciences 97 (25), 13967-13972, 2000 | 221 | 2000 |
| Structures of human A1 and A2A adenosine receptors with xanthines reveal determinants of selectivity RKY Cheng, E Segala, N Robertson, F Deflorian, AS Doré, JC Errey, ... Structure 25 (8), 1275-1285. e4, 2017 | 219 | 2017 |
| Extra-helical binding site of a glucagon receptor antagonist A Jazayeri, AS Doré, D Lamb, H Krishnamurthy, SM Southall, AH Baig, ... Nature 533 (7602), 274-277, 2016 | 214 | 2016 |
| Crystal structure of the GLP-1 receptor bound to a peptide agonist A Jazayeri, M Rappas, AJH Brown, J Kean, JC Errey, NJ Robertson, ... Nature 546 (7657), 254-258, 2017 | 201 | 2017 |
