NAD+‐dependent DNA ligase (Rv3014c) from Mycobacterium tuberculosis: Novel structure‐function relationship and identification of a specific inhibitor SK Srivastava, D Dube, V Kukshal, AK Jha, K Hajela, R Ramachandran Proteins: Structure, Function, and Bioinformatics 69 (1), 97-111, 2007 | 61 | 2007 |
NAD+‐Dependent DNA Ligase: A novel target waiting for the right inhibitor N Dwivedi, D Dube, J Pandey, B Singh, V Kukshal, R Ramachandran, ... Medicinal research reviews 28 (4), 545-568, 2008 | 47 | 2008 |
Mechanism of inhibition of the ATPase domain of human topoisomerase IIα by 1, 4-benzoquinone, 1, 2-naphthoquinone, 1, 4-naphthoquinone, and 9, 10-phenanthroquinone D Gurbani, V Kukshal, J Laubenthal, A Kumar, A Pandey, S Tripathi, ... Toxicological Sciences 126 (2), 372-390, 2012 | 46 | 2012 |
Bile acid receptor agonist GW4064 regulates PPARγ coactivator-1α expression through estrogen receptor-related receptor α SKD Dwivedi, N Singh, R Kumari, JS Mishra, S Tripathi, P Banerjee, ... Molecular endocrinology 25 (6), 922-932, 2011 | 45 | 2011 |
Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining V Kukshal, IK Kim, GL Hura, AE Tomkinson, JA Tainer, Ellenberger, Tom Nucl. Acids Res., 2015 | 30 | 2015 |
Chemical inhibition of the auxin inactivation pathway uncovers the roles of metabolic turnover in auxin homeostasis K Fukui, K Arai, Y Tanaka, Y Aoi, V Kukshal, JM Jez, MF Kubes, R Napier, ... Proceedings of the National Academy of Sciences 119 (32), e2206869119, 2022 | 19 | 2022 |
Crystal structure of the hexachlorocyclohexane dehydrochlorinase (LinA-type2): mutational analysis, thermostability and enantioselectivity AS Macwan, V Kukshal, N Srivastava, S Javed, A Kumar, ... PloS one 7 (11), e50373, 2012 | 17 | 2012 |
M. tuberculosis sliding β-clamp does not interact directly with the NAD+-dependent DNA ligase V Kukshal, T Khanam, D Chopra, N Singh, S Sanyal, R Ramachandran PLoS One 7 (4), e35702, 2012 | 17 | 2012 |
Chronologically modified androgen receptor in recurrent castration-resistant prostate cancer and its therapeutic targeting M Sawant, K Mahajan, A Renganathan, C Weimholt, J Luo, V Kukshal, ... Science translational medicine 14 (649), eabg4132, 2022 | 16 | 2022 |
Synthesis, in silico screening and bioevaluation of dispiro-cycloalkanones as antitubercular and mycobacterial NAD+-dependent DNA ligase inhibitors RP Tripathi, J Pandey, V Kukshal, A Ajay, M Mishra, D Dube, D Chopra, ... MedChemComm 2 (5), 378-384, 2011 | 15 | 2011 |
Beyond X-rays: an overview of emerging structural biology methods JE Schaffer, V Kukshal, JJ Miller, V Kitainda, JM Jez Emerging Topics in Life Sciences 33538291, 2021 | 12 | 2021 |
Phosphorylation-Dependent Conformations of the Disordered Carboxyl-Terminus Domain in the Epidermal Growth Factor Receptor Raju Regmi, Shwetha Srinivasan, Andrew P. Latham, Vandna Kukshal, Weidong ... Journal of Physical Chemistry Letters 11, 10037–10044, 2020 | 11 | 2020 |
The mitochondrial single-stranded DNA binding protein from S. cerevisiae, Rim1, does not form stable homo-tetramers and binds DNA as a dimer of dimers SP Singh, V Kukshal, P De Bona, E Antony, R Galletto Nucleic Acids Research, 2018 | 11 | 2018 |
Distribution and the evolutionary history of G-protein components in plant and algal lineages B Mohanasundaram, A Dodds, V Kukshal, JM Jez, S Pandey Plant Physiology 189 (3), 1519-1535, 2022 | 10 | 2022 |
Point mutations that boost aromatic amino acid production and CO2 assimilation in plants R Yokoyama, MVV de Oliveira, Y Takeda-Kimura, H Ishihara, S Alseekh, ... Science advances 8 (23), eabo3416, 2022 | 10 | 2022 |
NAD+-dependent DNA ligase (Rv3014c) from M. tuberculosis: Strategies for inhibitor design D Dube, V Kukshal, SK Srivastava, RP Tripathi, R Ramachandran Medicinal Chemistry Research 17, 189-198, 2008 | 9 | 2008 |
Synthesis and bioevaluation of aryl hydroxamates distinguishing between NAD+ and ATP-dependent DNA ligases V Kukshal, M Mishra, A Ajay, T Khanam, R Sharma, D Dube, D Chopra, ... MedChemComm 3 (4), 453-461, 2012 | 6 | 2012 |
A stable tetramer is not the only oligomeric state that mitochondrial single-stranded DNA binding proteins can adopt SP Singh, V Kukshal, R Galletto Journal of Biological Chemistry 294 (11), 4137-4144, 2019 | 4 | 2019 |
Chemical inhibition of auxin inactivation pathway uncovers the metabolic turnover of auxin homeostasis K Fukui, K Arai, Y Tanaka, Y Aoi, V Kukshal, JM Jez, MF Kubes, R Napier, ... bioRxiv, 2021.10. 12.464031, 2021 | 3 | 2021 |
Exploring Conformational Dynamics in EGFR using Single-Molecule Spectroscopy S Srinivasan, R Regmi, S Quinn, W He, V Kukshal, J Monsey, ... Biophysical Journal 116 (3), 279a, 2019 | | 2019 |