PGC-1 coactivators: inducible regulators of energy metabolism in health and disease BN Finck, DP Kelly The Journal of clinical investigation 116 (3), 615-622, 2006 | 1717 | 2006 |
Peroxisome proliferator–activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis JJ Lehman, PM Barger, A Kovacs, JE Saffitz, DM Medeiros, DP Kelly The Journal of clinical investigation 106 (7), 847-856, 2000 | 1579 | 2000 |
Transcriptional regulatory circuits controlling mitochondrial biogenesis and function DP Kelly, RC Scarpulla Genes & development 18 (4), 357-368, 2004 | 1446 | 2004 |
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor α in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes RB Vega, JM Huss, DP Kelly Molecular and cellular biology, 2000 | 1433 | 2000 |
Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC‐1 K Baar, AR Wende, TE Jones, M Marison, LA Nolte, MAY Chen, DP Kelly, ... The FASEB journal 16 (14), 1879-1886, 2002 | 1382 | 2002 |
The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus BN Finck, JJ Lehman, TC Leone, MJ Welch, MJ Bennett, A Kovacs, X Han, ... The Journal of clinical investigation 109 (1), 121-130, 2002 | 1207 | 2002 |
PGC-1α deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis TC Leone, JJ Lehman, BN Finck, PJ Schaeffer, AR Wende, S Boudina, ... PLoS biology 3 (4), e101, 2005 | 1192 | 2005 |
A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: the PPARα-null mouse as a model of fatty acid oxidation disorders TC Leone, CJ Weinheimer, DP Kelly Proceedings of the National Academy of Sciences 96 (13), 7473-7478, 1999 | 1164 | 1999 |
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1 LF Michael, Z Wu, RB Cheatham, P Puigserver, G Adelmant, JJ Lehman, ... Proceedings of the National Academy of Sciences 98 (7), 3820-3825, 2001 | 881 | 2001 |
Transcriptional integration of mitochondrial biogenesis RC Scarpulla, RB Vega, DP Kelly Trends in Endocrinology & Metabolism 23 (9), 459-466, 2012 | 848 | 2012 |
Fatty acid oxidation enzyme gene expression is downregulated in the failing heart MN Sack, TA Rader, S Park, J Bastin, SA McCune, DP Kelly Circulation 94 (11), 2837-2842, 1996 | 813 | 1996 |
The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. T Gulick, S Cresci, T Caira, DD Moore, DP Kelly Proceedings of the National Academy of Sciences 91 (23), 11012-11016, 1994 | 693 | 1994 |
Mitochondrial energy metabolism in heart failure: a question of balance JM Huss, DP Kelly The Journal of clinical investigation 115 (3), 547-555, 2005 | 664 | 2005 |
A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content BN Finck, X Han, M Courtois, F Aimond, JM Nerbonne, A Kovacs, ... Proceedings of the National Academy of Sciences 100 (3), 1226-1231, 2003 | 663 | 2003 |
Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway BN Finck, MC Gropler, Z Chen, TC Leone, MA Croce, TE Harris, ... Cell metabolism 4 (3), 199-210, 2006 | 654 | 2006 |
The failing heart relies on ketone bodies as a fuel G Aubert, OJ Martin, JL Horton, L Lai, RB Vega, TC Leone, T Koves, ... Circulation 133 (8), 698-705, 2016 | 643 | 2016 |
Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy VG Dávila-Román, G Vedala, P Herrero, L De Las Fuentes, JG Rogers, ... Journal of the American College of Cardiology 40 (2), 271-277, 2002 | 623 | 2002 |
PPAR signaling in the control of cardiac energy metabolism PM Barger, DP Kelly Trends in cardiovascular medicine 10 (6), 238-245, 2000 | 618 | 2000 |
Deactivation of peroxisome proliferator–activated receptor-α during cardiac hypertrophic growth PM Barger, JM Brandt, TC Leone, CJ Weinheimer, DP Kelly The Journal of clinical investigation 105 (12), 1723-1730, 2000 | 610 | 2000 |
Studying arrhythmogenic right ventricular dysplasia with patient-specific iPSCs C Kim, J Wong, J Wen, S Wang, C Wang, S Spiering, NG Kan, S Forcales, ... Nature 494 (7435), 105-110, 2013 | 605 | 2013 |