New insights into allosteric mechanisms from trapping unstable protein conformations in silica gels C Viappiani, S Bettati, S Bruno, L Ronda, S Abbruzzetti, A Mozzarelli, ... Proceedings of the National Academy of Sciences 101 (40), 14414-14419, 2004 | 130 | 2004 |
Haemoglobin-based oxygen carriers: research and reality towards an alternative to blood transfusions A Mozzarelli, L Ronda, S Faggiano, S Bettati, S Bruno Blood transfusion 8 (Suppl 3), s59, 2010 | 101 | 2010 |
Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling A Nakagawa, FE Lui, D Wassaf, R Yefidoff-Freedman, D Casalena, ... ACS chemical biology 9 (10), 2318-2325, 2014 | 63 | 2014 |
Iron metabolism at the interface between host and pathogen: from nutritional immunity to antibacterial development M Marchetti, O De Bei, S Bettati, B Campanini, S Kovachka, E Gianquinto, ... International journal of molecular sciences 21 (6), 2145, 2020 | 61 | 2020 |
Experimental basis for a new allosteric model for multisubunit proteins C Viappiani, S Abbruzzetti, L Ronda, S Bettati, ER Henry, A Mozzarelli, ... Proceedings of the National Academy of Sciences 111 (35), 12758-12763, 2014 | 58 | 2014 |
PEGylation promotes hemoglobin tetramer dissociation D Caccia, L Ronda, R Frassi, M Perrella, E Del Favero, S Bruno, B Pioselli, ... Bioconjugate chemistry 20 (7), 1356-1366, 2009 | 58 | 2009 |
Spectroscopic and functional characterization of T state hemoglobin conformations encapsulated in silica gels U Samuni, D Dantsker, LJ Juszczak, S Bettati, L Ronda, A Mozzarelli, ... Biochemistry 43 (43), 13674-13682, 2004 | 54 | 2004 |
Towards a novel haemoglobin-based oxygen carrier: Euro-PEG-Hb, physico-chemical properties, vasoactivity and renal filtration I Portörő, L Kocsis, P Herman, D Caccia, M Perrella, L Ronda, S Bruno, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (10), 1402-1409, 2008 | 50 | 2008 |
Evidence for two geminate rebinding states following laser photolysis of R state hemoglobin encapsulated in wet silica gels S Sottini, S Abbruzzetti, C Viappiani, S Bettati, L Ronda, A Mozzarelli The Journal of Physical Chemistry B 109 (23), 11411-11413, 2005 | 42 | 2005 |
Experiments on hemoglobin in single crystals and silica gels distinguish among allosteric models ER Henry, A Mozzarelli, C Viappiani, S Abbruzzetti, S Bettati, L Ronda, ... Biophysical Journal 109 (6), 1264-1272, 2015 | 40 | 2015 |
Oxygen binding to heme proteins in solution, encapsulated in silica gels, and in the crystalline state L Ronda, S Bruno, S Faggiano, S Bettati, A Mozzarelli Methods in enzymology 437, 311-328, 2008 | 39 | 2008 |
Circular dichroism spectroscopy of tertiary and quaternary conformations of human hemoglobin entrapped in wet silica gels L Ronda, S Bruno, C Viappiani, S Abbruzzetti, A Mozzarelli, KC Lowe, ... Protein science 15 (8), 1961-1967, 2006 | 37 | 2006 |
Geminate rebinding in R-state hemoglobin: kinetic and computational evidence for multiple hydrophobic pockets S Sottini, S Abbruzzetti, F Spyrakis, S Bettati, L Ronda, A Mozzarelli, ... Journal of the American Chemical Society 127 (49), 17427-17432, 2005 | 37 | 2005 |
Immobilization of proteins in silica gel: biochemical and biophysical properties L Ronda, S Bruno, B Campanini, A Mozzarelli, S Abbruzzetti, C Viappiani, ... Current Organic Chemistry 19 (17), 1653-1668, 2015 | 36 | 2015 |
Determination of microscopic rate constants for CO binding and migration in myoglobin encapsulated in silica gels S Sottini, S Abbruzzetti, C Viappiani, L Ronda, A Mozzarelli The Journal of Physical Chemistry B 109 (41), 19523-19528, 2005 | 36 | 2005 |
Engineering tyrosine electron transfer pathways decreases oxidative toxicity in hemoglobin: implications for blood substitute design GGA Silkstone, RS Silkstone, MT Wilson, M Simons, L Bülow, K Kallberg, ... Biochemical Journal 473 (19), 3371-3383, 2016 | 33 | 2016 |
Comparison of the oxidative reactivity of recombinant fetal and adult human hemoglobin: implications for the design of hemoglobin-based oxygen carriers M Simons, S Gretton, GGA Silkstone, BS Rajagopal, V Allen-Baume, ... Bioscience reports 38 (4), BSR20180370, 2018 | 31 | 2018 |
CO rebinding kinetics to myoglobin-and R-state-hemoglobin-doped silica gels in the presence of glycerol S Sottini, C Viappiani, L Ronda, S Bettati, A Mozzarelli The Journal of Physical Chemistry B 108 (24), 8475-8484, 2004 | 30 | 2004 |
Crystals of tryptophan indole-lyase and tyrosine phenol-lyase form stable quinonoid complexes RS Phillips, TV Demidkina, LN Zakomirdina, S Bruno, L Ronda, ... Journal of Biological Chemistry 277 (24), 21592-21597, 2002 | 30 | 2002 |
From hemoglobin allostery to hemoglobin-based oxygen carriers S Faggiano, L Ronda, S Bruno, S Abbruzzetti, C Viappiani, S Bettati, ... Molecular Aspects of Medicine 84, 101050, 2022 | 28 | 2022 |