Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4 K Ochiai, M Maienschein-Cline, G Simonetti, J Chen, R Rosenthal, ... Immunity 38 (5), 918-929, 2013 | 479 | 2013 |
Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits N Heise, NS De Silva, K Silva, A Carette, G Simonetti, M Pasparakis, ... Journal of Experimental Medicine 211 (10), 2103-2118, 2014 | 230 | 2014 |
Chronic myeloid leukemia stem cells M Houshmand, G Simonetti, P Circosta, V Gaidano, A Cignetti, ... Leukemia 33 (7), 1543-1556, 2019 | 170 | 2019 |
A WEE1 family business: regulation of mitosis, cancer progression, and therapeutic target AGL di Rorà, C Cerchione, G Martinelli, G Simonetti Journal of hematology & oncology 13 (1), 1-17, 2020 | 165 | 2020 |
The diverse roles of IRF4 in late germinal center B‐cell differentiation NS De Silva, G Simonetti, N Heise, U Klein Immunological reviews 247 (1), 73-92, 2012 | 160 | 2012 |
Optimized pipeline of MuTect and GATK tools to improve the detection of somatic single nucleotide polymorphisms in whole-exome sequencing data ÍF do Valle, E Giampieri, G Simonetti, A Padella, M Manfrini, A Ferrari, ... BMC bioinformatics 17 (12), 27-35, 2016 | 128 | 2016 |
Targeting macrophages sensitizes chronic lymphocytic leukemia to apoptosis and inhibits disease progression G Galletti, C Scielzo, F Barbaglio, TV Rodriguez, M Riba, D Lazarevic, ... Cell reports 14 (7), 1748-1760, 2016 | 122 | 2016 |
Mouse models in the study of chronic lymphocytic leukemia pathogenesis and therapy G Simonetti, MTS Bertilaccio, P Ghia, U Klein Blood, The Journal of the American Society of Hematology 124 (7), 1010-1019, 2014 | 102 | 2014 |
HS1 has a central role in the trafficking and homing of leukemic B cells C Scielzo, MTS Bertilaccio, G Simonetti, A Dagklis, E Ten Hacken, C Fazi, ... Blood, The Journal of the American Society of Hematology 116 (18), 3537-3546, 2010 | 96 | 2010 |
Aneuploidy: Cancer strength or vulnerability? G Simonetti, S Bruno, A Padella, E Tenti, G Martinelli International journal of cancer 144 (1), 8-25, 2019 | 95 | 2019 |
A novel Rag2−/−γc−/−-xenograft model of human CLL MTS Bertilaccio, C Scielzo, G Simonetti, M Ponzoni, B Apollonio, C Fazi, ... Blood, The Journal of the American Society of Hematology 115 (8), 1605-1609, 2010 | 92 | 2010 |
Chromothripsis in acute myeloid leukemia: biological features and impact on survival MC Fontana, G Marconi, JDM Feenstra, E Fonzi, C Papayannidis, ... Leukemia 32 (7), 1609-1620, 2018 | 91 | 2018 |
IRF4 controls the positioning of mature B cells in the lymphoid microenvironments by regulating NOTCH2 expression and activity G Simonetti, A Carette, K Silva, H Wang, NS De Silva, N Heise, CW Siebel, ... Journal of Experimental Medicine 210 (13), 2887-2902, 2013 | 73 | 2013 |
Linear and circular PVT1 in hematological malignancies and immune response: two faces of the same coin M Ghetti, I Vannini, CT Storlazzi, G Martinelli, G Simonetti Molecular cancer 19 (1), 1-15, 2020 | 64 | 2020 |
Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models MTS Bertilaccio, G Simonetti, A Dagklis, M Rocchi, TV Rodriguez, ... Blood, The Journal of the American Society of Hematology 118 (3), 660-669, 2011 | 61 | 2011 |
Aneuploid acute myeloid leukemia exhibits a signature of genomic alterations in the cell cycle and protein degradation machinery G Simonetti, A Padella, IF do Valle, MC Fontana, E Fonzi, S Bruno, ... Cancer 125 (5), 712-725, 2019 | 57 | 2019 |
Main changes in European clinical trials regulation (no 536/2014) E Tenti, G Simonetti, MT Bochicchio, G Martinelli Contemporary clinical trials communications 11, 99-101, 2018 | 52 | 2018 |
Xenograft models of chronic lymphocytic leukemia: problems, pitfalls and future directions MTS Bertilaccio, C Scielzo, G Simonetti, E Ten Hacken, B Apollonio, ... Leukemia 27 (3), 534-540, 2013 | 52 | 2013 |
Biomarkers for pancreatic neuroendocrine neoplasms (PanNENs) management—an updated review M Bocchini, F Nicolini, S Severi, A Bongiovanni, T Ibrahim, G Simonetti, ... Frontiers in Oncology 10, 831, 2020 | 50 | 2020 |
The role of Toll-like receptors in chronic B cell malignancies M Muzio, MTS Bertilaccio, G Simonetti, M Frenquelli, F Caligaris-Cappio Leukemia & lymphoma 50 (10), 1573-1580, 2009 | 46 | 2009 |