Systemic inflammation in decompensated cirrhosis: characterization and role in acute‐on‐chronic liver failure J Clària, RE Stauber, MJ Coenraad, R Moreau, R Jalan, M Pavesi, ... Hepatology 64 (4), 1249-1264, 2016 | 722 | 2016 |
Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction in patients with malignant hemopathies: the OVERCOME trial (preventiOn of … X Bosch, M Rovira, M Sitges, A Domènech, JT Ortiz-Pérez, TM de Caralt, ... Journal of the American College of Cardiology 61 (23), 2355-2362, 2013 | 707 | 2013 |
Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase–Akt pathway in human endothelial cells MP Haynes, D Sinha, KS Russell, M Collinge, D Fulton, M Morales-Ruiz, ... Circulation research 87 (8), 677-682, 2000 | 703 | 2000 |
Vascular endothelial growth factor–stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt M Morales-Ruiz, D Fulton, G Sowa, LR Languino, Y Fujio, K Walsh, ... Circulation research 86 (8), 892-896, 2000 | 518 | 2000 |
Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting M Mesri, M Morales-Ruiz, EJ Ackermann, CF Bennett, JS Pober, ... The American journal of pathology 158 (5), 1757-1765, 2001 | 516 | 2001 |
Akt-mediated phosphorylation of the G protein-coupled receptor EDG-1 is required for endothelial cell chemotaxis MJ Lee, S Thangada, JH Paik, GP Sapkota, N Ancellin, SS Chae, M Wu, ... Molecular cell 8 (3), 693-704, 2001 | 387 | 2001 |
Akt down-regulation of p38 signaling provides a novel mechanism of vascular endothelial growth factor-mediated cytoprotection in endothelial cells JP Gratton, M Morales-Ruiz, Y Kureishi, D Fulton, K Walsh, WC Sessa Journal of Biological Chemistry 276 (32), 30359-30365, 2001 | 325 | 2001 |
Antiangiogenic treatment with sunitinib ameliorates inflammatory infiltrate, fibrosis, and portal pressure in cirrhotic rats S Tugues, G Fernandez‐Varo, J Muñoz‐Luque, J Ros, V Arroyo, J Rodés, ... Hepatology 46 (6), 1919-1926, 2007 | 319 | 2007 |
Sphingosine 1-phosphate activates Akt, nitric oxide production, and chemotaxis through a Giprotein/phosphoinositide 3-kinase pathway in endothelial cells M Morales-Ruiz, MJ Lee, S Zöllner, JP Gratton, R Scotland, I Shiojima, ... Journal of Biological Chemistry 276 (22), 19672-19677, 2001 | 319 | 2001 |
Further pharmacological and genetic evidence for the efficacy of PlGF inhibition in cancer and eye disease S Van de Veire, I Stalmans, F Heindryckx, H Oura, A Tijeras-Raballand, ... Cell 141 (1), 178-190, 2010 | 303 | 2010 |
Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial F Torrico, J Gascon, L Ortiz, C Alonso-Vega, MJ Pinazo, A Schijman, ... The Lancet Infectious Diseases 18 (4), 419-430, 2018 | 280 | 2018 |
Effects of albumin treatment on systemic and portal hemodynamics and systemic inflammation in patients with decompensated cirrhosis J Fernández, J Clària, A Amorós, F Aguilar, M Castro, M Casulleras, ... Gastroenterology 157 (1), 149-162, 2019 | 229 | 2019 |
Regression of fibrosis after chronic stimulation of cannabinoid CB2 receptor in cirrhotic rats J Muñoz-Luque, J Ros, G Fernández-Varo, S Tugues, M Morales-Ruiz, ... Journal of Pharmacology and Experimental Therapeutics 324 (2), 475-483, 2008 | 209 | 2008 |
Mir-33 regulates cell proliferation and cell cycle progression D Cirera-Salinas, M Pauta, RM Allen, AG Salerno, CM Ramírez, ... Cell cycle 11 (5), 922-933, 2012 | 192 | 2012 |
The hepatic apelin system: a new therapeutic target for liver disease A Principe, P Melgar‐Lesmes, G Fernández‐Varo, LR del Arbol, J Ros, ... Hepatology 48 (4), 1193-1201, 2008 | 174 | 2008 |
Increased nitric oxide synthase expression in arterial vessels of cirrhotic rats with ascites M Morales-Ruiz, W Jimenez, D Perez-Sala, J Ros, A Leivas, S Lamas, ... Hepatology 24 (6), 1481-1486, 1996 | 163 | 1996 |
Transduction of the liver with activated Akt normalizes portal pressure in cirrhotic rats M Morales-Ruiz, P Cejudo-martı́n, G Fernández-Varo, S Tugues, J Ros, ... Gastroenterology 125 (2), 522-531, 2003 | 162 | 2003 |
Neutrophil gelatinase‐associated lipocalin for assessment of acute kidney injury in cirrhosis: a prospective study P Huelin, E Solà, C Elia, C Solé, A Risso, R Moreira, M Carol, N Fabrellas, ... Hepatology 70 (1), 319-333, 2019 | 160 | 2019 |
Neutrophil gelatinase-associated lipocalin is a biomarker of acute-on-chronic liver failure and prognosis in cirrhosis X Ariza, I Graupera, M Coll, E Solà, R Barreto, E García, R Moreira, C Elia, ... Journal of hepatology 65 (1), 57-65, 2016 | 159 | 2016 |
Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates MY Lee, AK Luciano, E Ackah, J Rodriguez-Vita, TA Bancroft, A Eichmann, ... Proceedings of the National Academy of Sciences 111 (35), 12865-12870, 2014 | 157 | 2014 |