| Androgen levels increase by intratumoral de novo steroidogenesis during progression of castration-resistant prostate cancer JA Locke, ES Guns, AA Lubik, HH Adomat, SC Hendy, CA Wood, ... Cancer research 68 (15), 6407-6415, 2008 | 954 | 2008 |
| Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy X Li, AL Corbett, E Taatizadeh, N Tasnim, JP Little, C Garnis, M Daugaard, ... APL bioengineering 3 (1), 2019 | 437 | 2019 |
| Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles VR Minciacchi, S You, C Spinelli, S Morley, M Zandian, PJ Aspuria, ... Oncotarget 6 (13), 11327, 2015 | 379 | 2015 |
| Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance MJ Newman, JC Rodarte, KD Benbatoul, SJ Romano, C Zhang, S Krane, ... Cancer research 60 (11), 2964-2972, 2000 | 302 | 2000 |
| Reproducibility and efficiency of serum-derived exosome extraction methods J Caradec, G Kharmate, E Hosseini-Beheshti, H Adomat, M Gleave, ... Clinical biochemistry 47 (13-14), 1286-1292, 2014 | 278 | 2014 |
| Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes E Hosseini-Beheshti, S Pham, H Adomat, N Li, EST Guns Molecular & Cellular Proteomics 11 (10), 863-885, 2012 | 260 | 2012 |
| Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration‐resistant prostate cancer in a mouse xenograft model CG Leon, JA Locke, HH Adomat, SL Etinger, AL Twiddy, RD Neumann, ... The Prostate 70 (4), 390-400, 2010 | 194 | 2010 |
| Targeting the binding function 3 (BF3) site of the human androgen receptor through virtual screening. NA Lack, P Axerio-Cilies, P Tavassoli, FQ Han, KH Chan, C Feau, ... Journal of medicinal chemistry 54 (24), 8563-8573, 2011 | 186 | 2011 |
| Bioactive compounds from Rhodiola rosea (Crassulaceae) DS Ming, BJ Hillhouse, ES Guns, A Eberding, S Xie, S Vimalanathan, ... Phytotherapy Research: An International Journal Devoted to Pharmacological …, 2005 | 176 | 2005 |
| Lycopene differentially induces quiescence and apoptosis in androgen-responsive and-independent prostate cancer cell lines NI Ivanov, SP Cowell, P Brown, PS Rennie, ES Guns, ME Cox Clinical Nutrition 26 (2), 252-263, 2007 | 159 | 2007 |
| Selectively targeting the DNA-binding domain of the androgen receptor as a prospective therapy for prostate cancer K Dalal, M Roshan-Moniri, A Sharma, H Li, F Ban, M Hessein, M Hsing, ... Journal of biological chemistry 289 (38), 26417-26429, 2014 | 147 | 2014 |
| A population-based survey of complementary and alternative medicine use in men recently diagnosed with prostate cancer J Eng, D Ramsum, M Verhoef, E Guns, J Davison, R Gallagher Integrative cancer therapies 2 (3), 212-216, 2003 | 147 | 2003 |
| A phase I study of OGX-011, a 2′-methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancer KN Chi, LL Siu, H Hirte, SJ Hotte, J Knox, C Kollmansberger, M Gleave, ... Clinical cancer research 14 (3), 833-839, 2008 | 140 | 2008 |
| Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation. DM Gentile, ES Tomlinson, JL Maggs, BK Park, DJ Back Journal of Pharmacology and Experimental Therapeutics 277 (1), 105-112, 1996 | 139 | 1996 |
| DMSO represses inflammatory cytokine production from human blood cells and reduces autoimmune arthritis I Elisia, H Nakamura, V Lam, E Hofs, R Cederberg, J Cait, MR Hughes, ... PloS one 11 (3), e0152538, 2016 | 125 | 2016 |
| Inhibitors of androgen receptor activation function-2 (AF2) site identified through virtual screening P Axerio-Cilies, NA Lack, MRS Nayana, KH Chan, A Yeung, E Leblanc, ... Journal of medicinal chemistry 54 (18), 6197-6205, 2011 | 110 | 2011 |
| Randomized phase II study of high-dose paclitaxel with or without amifostine in patients with metastatic breast cancer K Gelmon, E Eisenhauer, C Bryce, A Tolcher, L Mayer, E Tomlinson, ... Journal of clinical oncology 17 (10), 3038-3047, 1999 | 108 | 1999 |
| Dexamethasone metabolism in vitro: species differences ES Tomlinson, JL Maggs, BK Park, DJ Back The Journal of steroid biochemistry and molecular biology 62 (4), 345-352, 1997 | 108 | 1997 |
| Anticancer activity of a novel selective CYP17A1 inhibitor in preclinical models of castrate-resistant prostate cancer PJ Toren, S Kim, S Pham, A Mangalji, H Adomat, EST Guns, A Zoubeidi, ... Molecular cancer therapeutics 14 (1), 59-69, 2015 | 98 | 2015 |
| Effect of noncompetitive proteasome inhibition on bortezomib resistance X Li, TE Wood, R Sprangers, G Jansen, NE Franke, X Mao, X Wang, ... JNCI: Journal of the National Cancer Institute 102 (14), 1069-1082, 2010 | 97 | 2010 |
