关注
Guoyan Xu
Guoyan Xu
Virginia Commonwealth University, Virginia Tech
在 vt.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Pin1 as an anticancer drug target.
GG Xu, FA Etzkorn
Drug news & perspectives 22 (7), 399-407, 2009
712009
Chemokine Receptor CCR5 Antagonist Maraviroc: Medicinal Chemistry and Clinical Applications
GG Xu, J Guo, Y Wu
Current Topics in Medicinal Chemistry 14 (13), 1504-1514, 2014
582014
Convergent synthesis of α-ketoamide inhibitors of Pin1
GG Xu, FA Etzkorn
Organic letters 12 (4), 696-699, 2010
462010
A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state
GG Xu, Y Zhang, AY Mercedes-Camacho, FA Etzkorn
Biochemistry 50 (44), 9545-9550, 2011
402011
Reaction of nitrile oxides with vinylphosphonate: A facile, regioselective approach to 5‐phosphonyl‐4, 5‐dihydroisoxazoles
Y Ye, Y Zheng, GY Xu, LZ Liu
Heteroatom Chemistry: An International Journal of Main Group Elements 14 (3 …, 2003
342003
Kinetic isotope effects support the twisted amide mechanism of Pin1 peptidyl-prolyl isomerase
AY Mercedes-Camacho, AB Mullins, MD Mason, GG Xu, BJ Mahoney, ...
Biochemistry 52 (44), 7707-7713, 2013
282013
Cyclohexyl Ketone Inhibitors of Pin1 Dock in a Trans-Diaxial Cyclohexane Conformation
GG Xu, C Slebodnick, FA Etzkorn
Public Library of Science 7 (9), e44226, 2012
192012
1, 3-dipolar cycloaddition reactions of nitrones to prop-1-ene-1, 3-sultone
L Tian, GY Xu, Y Ye, LZ Liu
Synthesis 2003 (09), 1329-1334, 2003
162003
Cycloaddition of nitrile oxides to substituted vinylphosphonates
Y Ye, GY Xu, Y Zheng, LZ Liu
Heteroatom Chemistry: An International Journal of Main Group Elements 14 (4 …, 2003
152003
1, 3‐dipolar cycloaddition reactions of nitrile oxides to prop‐1‐ene‐1, 3‐sultone
L Tian, GY Xu, Y Ye, LZ Liu
Journal of heterocyclic chemistry 40 (6), 1071-1074, 2003
142003
Exploration on natural product anibamine side chain modification toward development of novel CCR5 antagonists and potential anti-prostate cancer agents
GG Xu, SA Zaidi, F Zhang, S Singh, TJ Raborg, Y Yuan, Y Zhang
Bioorganic & medicinal chemistry letters 25 (17), 3721-3725, 2015
82015
The reaction of PhCH2C(O)NR2/P(O)Cl3 with phosphites and hydridophosphorane
WH Wang, GY Xu, RZ Cao, LZ Liu
Heteroatom Chemistry: An International Journal of Main Group Elements 11 (7 …, 2000
82000
Vzhe-039, a novel structurally-enhanced allosteric hemoglobin effector inhibits sickling of SS erythrocytes in vitro, and exhibits improved pharmacologic properties In Vivo
MK Safo, G Xu, M Ghatge, Q Chen, C Casu, D Tanya, Y Zhang, J Venitz, ...
Blood 128 (22), 3645, 2016
32016
Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease
MK Safo, Y Zhang, PP Pagare, XU Guoyan, M Ghatge, J Venitz, ...
US Patent 11,401,241, 2022
22022
Prodrug and protected forms of 5-hydroxymethylfurfuranal (5-HMF) and its derivatives
MK Safo, XU Guoyan, Y Zhang, O Abdulmalik
US Patent 10,875,834, 2020
22020
Pin1 Inhibitors: Towards Understanding the Enzymatic Mechanism
G Xu
Virginia Tech, 2010
22010
Benzaldehyde compounds with direct polymer destabilizing effects to treat sickle cell disease
M Safo, Y Zhang, PP Pagare, XU Guoyan, M Ghatge, J Venitz, ...
US Patent App. 18/501,244, 2024
2024
Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease
MK Safo, Y Zhang, PP Pagare, XU Guoyan, M Ghatge, J Venitz, ...
US Patent App. 17/846,101, 2022
2022
BIOL 57-Design and synthesis of amine and ketone inhibitors of PIN1
GG Xu, FA Etzkorn
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, 2008
2008
Synthesis of a potential transition-state analogue inhibitor for Pin1
GG Xu, FA Etzkorn
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230, U591-U592, 2005
2005
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