Pin1 as an anticancer drug target. GG Xu, FA Etzkorn Drug news & perspectives 22 (7), 399-407, 2009 | 71 | 2009 |
Chemokine Receptor CCR5 Antagonist Maraviroc: Medicinal Chemistry and Clinical Applications GG Xu, J Guo, Y Wu Current Topics in Medicinal Chemistry 14 (13), 1504-1514, 2014 | 58 | 2014 |
Convergent synthesis of α-ketoamide inhibitors of Pin1 GG Xu, FA Etzkorn Organic letters 12 (4), 696-699, 2010 | 46 | 2010 |
A reduced-amide inhibitor of Pin1 binds in a conformation resembling a twisted-amide transition state GG Xu, Y Zhang, AY Mercedes-Camacho, FA Etzkorn Biochemistry 50 (44), 9545-9550, 2011 | 40 | 2011 |
Reaction of nitrile oxides with vinylphosphonate: A facile, regioselective approach to 5‐phosphonyl‐4, 5‐dihydroisoxazoles Y Ye, Y Zheng, GY Xu, LZ Liu Heteroatom Chemistry: An International Journal of Main Group Elements 14 (3 …, 2003 | 34 | 2003 |
Kinetic isotope effects support the twisted amide mechanism of Pin1 peptidyl-prolyl isomerase AY Mercedes-Camacho, AB Mullins, MD Mason, GG Xu, BJ Mahoney, ... Biochemistry 52 (44), 7707-7713, 2013 | 28 | 2013 |
Cyclohexyl Ketone Inhibitors of Pin1 Dock in a Trans-Diaxial Cyclohexane Conformation GG Xu, C Slebodnick, FA Etzkorn Public Library of Science 7 (9), e44226, 2012 | 19 | 2012 |
1, 3-dipolar cycloaddition reactions of nitrones to prop-1-ene-1, 3-sultone L Tian, GY Xu, Y Ye, LZ Liu Synthesis 2003 (09), 1329-1334, 2003 | 16 | 2003 |
Cycloaddition of nitrile oxides to substituted vinylphosphonates Y Ye, GY Xu, Y Zheng, LZ Liu Heteroatom Chemistry: An International Journal of Main Group Elements 14 (4 …, 2003 | 15 | 2003 |
1, 3‐dipolar cycloaddition reactions of nitrile oxides to prop‐1‐ene‐1, 3‐sultone L Tian, GY Xu, Y Ye, LZ Liu Journal of heterocyclic chemistry 40 (6), 1071-1074, 2003 | 14 | 2003 |
Exploration on natural product anibamine side chain modification toward development of novel CCR5 antagonists and potential anti-prostate cancer agents GG Xu, SA Zaidi, F Zhang, S Singh, TJ Raborg, Y Yuan, Y Zhang Bioorganic & medicinal chemistry letters 25 (17), 3721-3725, 2015 | 8 | 2015 |
The reaction of PhCH2C(O)NR2/P(O)Cl3 with phosphites and hydridophosphorane WH Wang, GY Xu, RZ Cao, LZ Liu Heteroatom Chemistry: An International Journal of Main Group Elements 11 (7 …, 2000 | 8 | 2000 |
Vzhe-039, a novel structurally-enhanced allosteric hemoglobin effector inhibits sickling of SS erythrocytes in vitro, and exhibits improved pharmacologic properties In Vivo MK Safo, G Xu, M Ghatge, Q Chen, C Casu, D Tanya, Y Zhang, J Venitz, ... Blood 128 (22), 3645, 2016 | 3 | 2016 |
Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease MK Safo, Y Zhang, PP Pagare, XU Guoyan, M Ghatge, J Venitz, ... US Patent 11,401,241, 2022 | 2 | 2022 |
Prodrug and protected forms of 5-hydroxymethylfurfuranal (5-HMF) and its derivatives MK Safo, XU Guoyan, Y Zhang, O Abdulmalik US Patent 10,875,834, 2020 | 2 | 2020 |
Pin1 Inhibitors: Towards Understanding the Enzymatic Mechanism G Xu Virginia Tech, 2010 | 2 | 2010 |
Benzaldehyde compounds with direct polymer destabilizing effects to treat sickle cell disease M Safo, Y Zhang, PP Pagare, XU Guoyan, M Ghatge, J Venitz, ... US Patent App. 18/501,244, 2024 | | 2024 |
Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease MK Safo, Y Zhang, PP Pagare, XU Guoyan, M Ghatge, J Venitz, ... US Patent App. 17/846,101, 2022 | | 2022 |
BIOL 57-Design and synthesis of amine and ketone inhibitors of PIN1 GG Xu, FA Etzkorn ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 235, 2008 | | 2008 |
Synthesis of a potential transition-state analogue inhibitor for Pin1 GG Xu, FA Etzkorn ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 230, U591-U592, 2005 | | 2005 |