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Helen Lee
Helen Lee
在 sanofi.com 的电子邮件经过验证
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The effects of particle size and molecular targeting on the intratumoral and subcellular distribution of polymeric nanoparticles
H Lee, H Fonge, B Hoang, RM Reilly, C Allen
Molecular Pharmaceutics 7 (4), 1195-1208, 2010
3832010
64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response …
H Lee, AF Shields, BA Siegel, KD Miller, I Krop, CX Ma, PM LoRusso, ...
Clinical Cancer Research 23 (15), 4190-4202, 2017
3312017
Formulation of drugs in block copolymer micelles: drug loading and release
J Liu, H Lee, C Allen
Current pharmaceutical design 12 (36), 4685-4701, 2006
1682006
Nanotechnology for cancer therapy (Chapter 17. Polymeric Micelles for Formulation of Anti-Cancer Drugs)
H Lee, P Lim Soo, J Liu, B Mark, C Allen, MM Amiji (editor)
CRC Press, 2007
164*2007
In vivo distribution of polymeric nanoparticles at the whole-body, tumor, and cellular levels
H Lee, B Hoang, H Fonge, RM Reilly, C Allen
Pharmaceutical research 27 (11), 2343-2355, 2010
1512010
Epidermal growth factor-conjugated poly (ethylene glycol)-block-poly (δ-valerolactone) copolymer micelles for targeted delivery of chemotherapeutics
F Zeng, H Lee, C Allen
Bioconjugate chemistry 17 (2), 399-409, 2006
1472006
HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity
JG Reynolds, E Geretti, BS Hendriks, H Lee, SC Leonard, SG Klinz, ...
Toxicology and applied pharmacology 262 (1), 1-10, 2012
1422012
Methoxy poly (ethylene glycol)-block-poly (δ-valerolactone) copolymer micelles for formulation of hydrophobic drugs
H Lee, F Zeng, M Dunne, C Allen
Biomacromolecules 6 (6), 3119-3128, 2005
1262005
Noninvasive monitoring of the fate of 111In-labeled block copolymer micelles by high resolution and high sensitivity microSPECT/CT imaging
B Hoang, H Lee, RM Reilly, C Allen
Molecular pharmaceutics 6 (2), 581-592, 2009
1172009
Antitumor effects and normal-tissue toxicity of 111In-nuclear localization sequence-trastuzumab in athymic mice bearing HER-positive human breast cancer xenografts
DL Costantini, K McLarty, H Lee, SJ Done, KA Vallis, RM Reilly
Journal of Nuclear Medicine 51 (7), 1084, 2010
902010
Photodynamic priming mitigates chemotherapeutic selection pressures and improves drug delivery
HC Huang, I Rizvi, J Liu, S Anbil, A Kalra, H Lee, Y Baglo, N Paz, ...
Cancer research 78 (2), 558-571, 2018
852018
A gradient-loadable 64 Cu-chelator for quantifying tumor deposition kinetics of nanoliposomal therapeutics by positron emission tomography
H Lee, J Zheng, D Gaddy, KD Orcutt, S Leonard, E Geretti, J Hesterman, ...
Nanomedicine: Nanotechnology, Biology and Medicine 11 (1), 155-165, 2015
762015
Apoptotic epidermal growth factor (EGF)-conjugated block copolymer micelles as a nanotechnology platform for targeted combination therapy
H Lee, M Hu, RM Reilly, C Allen
Molecular Pharmaceutics 4 (5), 769-781, 2007
752007
Cyclophosphamide-mediated tumor priming for enhanced delivery and antitumor activity of HER2-targeted liposomal doxorubicin (MM-302)
E Geretti, SC Leonard, N Dumont, H Lee, J Zheng, R De Souza, ...
Molecular cancer therapeutics 14 (9), 2060-2071, 2015
732015
Liposome formulation of a novel hydrophobic aryl-imidazole compound for anti-cancer therapy
J Liu, H Lee, M Huesca, A Young, C Allen
Cancer chemotherapy and pharmacology 58, 306-318, 2006
672006
Liposomal irinotecan accumulates in metastatic lesions, crosses the blood-tumor barrier (BTB), and prolongs survival in an experimental model of brain metastases of triple …
AS Mohammad, JI Griffith, CE Adkins, N Shah, E Sechrest, EL Dolan, ...
Pharmaceutical research 35, 1-10, 2018
632018
Multiscale Kinetic Modeling of Liposomal Doxorubicin Delivery Quantifies the Role of Tumor and Drug‐Specific Parameters in Local Delivery to Tumors
BS Hendriks, JG Reynolds, SG Klinz, E Geretti, H Lee, SC Leonard, ...
CPT: Pharmacometrics & Systems Pharmacology 1 (11), 1-11, 2012
632012
Synthesis and Characterization of Six-Arm Star Poly (δ-valerolactone)-b lock-Methoxy Poly (ethylene glycol) Copolymers
F Zeng, H Lee, M Chidiac, C Allen
Biomacromolecules 6 (4), 2140-2149, 2005
582005
Companion Diagnostic 64Cu-Liposome Positron Emission Tomography Enables Characterization of Drug Delivery to Tumors and Predicts Response to Cancer Nanomedicines
H Lee, D Gaddy, M Ventura, N Bernards, R de Souza, D Kirpotin, ...
Theranostics 8 (9), 2300, 2018
552018
Intermolecular interactions and morphology of aqueous polymer/surfactant mixtures containing cationic chitosan and nonionic sorbitan esters
J Grant, H Lee, RCW Liu, C Allen
Biomacromolecules 9 (8), 2146-2152, 2008
462008
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