AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC V Hornung, A Ablasser, M Charrel-Dennis, F Bauernfeind, G Horvath, ... Nature 458 (7237), 514-518, 2009 | 2816 | 2009 |
LPS-TLR4 signaling to IRF-3/7 and NF-κB involves the toll adapters TRAM and TRIF KA Fitzgerald, DC Rowe, BJ Barnes, DR Caffrey, A Visintin, E Latz, ... The Journal of experimental medicine 198 (7), 1043-1055, 2003 | 1610 | 2003 |
A long noncoding RNA mediates both activation and repression of immune response genes S Carpenter, D Aiello, MK Atianand, EP Ricci, P Gandhi, LL Hall, M Byron, ... science 341 (6147), 789-792, 2013 | 1034 | 2013 |
Structure-based maximal affinity model predicts small-molecule druggability AC Cheng, RG Coleman, KT Smyth, Q Cao, P Soulard, DR Caffrey, ... Nature biotechnology 25 (1), 71-75, 2007 | 775 | 2007 |
Genomic insights into the Ixodes scapularis tick vector of Lyme disease M Gulia-Nuss, AB Nuss, JM Meyer, DE Sonenshine, RM Roe, ... Nature communications 7 (1), 10507, 2016 | 505 | 2016 |
Are protein–protein interfaces more conserved in sequence than the rest of the protein surface? DR Caffrey, S Somaroo, JD Hughes, J Mintseris, ES Huang Protein Science 13 (1), 190-202, 2004 | 462 | 2004 |
A long noncoding RNA lincRNA-EPS acts as a transcriptional brake to restrain inflammation MK Atianand, W Hu, AT Satpathy, Y Shen, EP Ricci, ... Cell 165 (7), 1672-1685, 2016 | 437 | 2016 |
Immunobiology of long noncoding RNAs MK Atianand, DR Caffrey, KA Fitzgerald Annual review of immunology 35 (1), 177-198, 2017 | 432 | 2017 |
Long noncoding RNAs in innate and adaptive immunity KA Fitzgerald, DR Caffrey Current opinion in immunology 26, 140-146, 2014 | 240 | 2014 |
Of mice and man: TLR11 (finally) finds profilin FN Lauw, DR Caffrey, DT Golenbock Trends in immunology 26 (10), 509-511, 2005 | 197 | 2005 |
The evolution of the MAP kinase pathways: coduplication of interacting proteins leads to new signaling cascades DR Caffrey, LA O'neill, DC Shields Journal of molecular evolution 49, 567-582, 1999 | 161 | 1999 |
Influenza virus drug resistance: a time-sampled population genetics perspective M Foll, YP Poh, N Renzette, A Ferrer-Admetlla, C Bank, H Shim, ... PLoS genetics 10 (2), e1004185, 2014 | 142 | 2014 |
The Genome of Anopheles darlingi , the main neotropical malaria vector O Marinotti, GC Cerqueira, LGP De Almeida, MIT Ferro, ELS Loreto, ... Nucleic acids research 41 (15), 7387-7400, 2013 | 137 | 2013 |
siRNA off-target effects can be reduced at concentrations that match their individual potency DR Caffrey, J Zhao, Z Song, ME Schaffer, SA Haney, RR Subramanian, ... PloS one 6 (7), e21503, 2011 | 129 | 2011 |
Cutting edge: a natural antisense transcript, AS-IL1α, controls inducible transcription of the proinflammatory cytokine IL-1α J Chan, M Atianand, Z Jiang, S Carpenter, D Aiello, R Elling, ... The journal of immunology 195 (4), 1359-1363, 2015 | 120 | 2015 |
PFAAT version 2.0: a tool for editing, annotating, and analyzing multiple sequence alignments DR Caffrey, PH Dana, V Mathur, M Ocano, EJ Hong, YE Wang, ... BMC bioinformatics 8, 1-7, 2007 | 70 | 2007 |
SLC46 family transporters facilitate cytosolic innate immune recognition of monomeric peptidoglycans D Paik, A Monahan, DR Caffrey, R Elling, WE Goldman, N Silverman The Journal of Immunology 199 (1), 263-270, 2017 | 52 | 2017 |
Evolution of the Influenza A Virus Genome during Development of Oseltamivir Resistance In Vitro N Renzette, DR Caffrey, KB Zeldovich, P Liu, GR Gallagher, D Aiello, ... Journal of Virology 88 (1), 272-281, 2014 | 52 | 2014 |
Distinct cellular origins for serotonin-expressing and enterochromaffin-like cells in the gastric corpus HJ Li, B Johnston, D Aiello, DR Caffrey, M Giel–Moloney, G Rindi, ... Gastroenterology 146 (3), 754-764. e3, 2014 | 49 | 2014 |
miR-718 represses proinflammatory cytokine production through targeting phosphatase and tensin homolog (PTEN) P Kalantari, OF Harandi, S Agarwal, F Rus, EA Kurt-Jones, KA Fitzgerald, ... Journal of Biological Chemistry 292 (14), 5634-5644, 2017 | 47 | 2017 |