Asymmetric T lymphocyte division in the initiation of adaptive immune responses JT Chang, VR Palanivel, I Kinjyo, F Schambach, AM Intlekofer, ... science 315 (5819), 1687-1691, 2007 | 1074 | 2007 |
SOCS1/JAB is a negative regulator of LPS-induced macrophage activation I Kinjyo, T Hanada, K Inagaki-Ohara, H Mori, D Aki, M Ohishi, H Yoshida, ... Immunity 17 (5), 583-591, 2002 | 821 | 2002 |
Cytokine‐inducible SH2 protein‐3 (CIS3/SOCS3) inhibits Janus tyrosine kinase by binding through the N‐terminal kinase inhibitory region as well as SH2 domain A Sasaki, H Yasukawa, A Suzuki, S Kamizono, T Syoda, I Kinjyo, ... Genes to Cells 4 (6), 339-351, 1999 | 545 | 1999 |
Involvement of suppressor of cytokine signaling-3 as a mediator of the inhibitory effects of IL-10 on lipopolysaccharide-induced macrophage activation C Berlato, MA Cassatella, I Kinjyo, L Gatto, A Yoshimura, F Bazzoni The Journal of Immunology 168 (12), 6404-6411, 2002 | 365 | 2002 |
Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on … T Yoshimura, A Takeda, S Hamano, Y Miyazaki, I Kinjyo, T Ishibashi, ... The Journal of Immunology 177 (8), 5377-5385, 2006 | 332 | 2006 |
Loss of SOCS3 in the liver promotes fibrosis by enhancing STAT3-mediated TGF-β 1 production H Ogata, T Chinen, T Yoshida, I Kinjyo, G Takaesu, H Shiraishi, M Iida, ... Oncogene 25 (17), 2520-2530, 2006 | 298 | 2006 |
Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK‐STAT5 pathway. A Yoshimura, M Ichihara, I Kinjyo, M Moriyama, NG Copeland, DJ Gilbert, ... The EMBO journal 15 (5), 1055-1063, 1996 | 269 | 1996 |
Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor–β1 I Kinjyo, H Inoue, S Hamano, S Fukuyama, T Yoshimura, K Koga, ... The Journal of experimental medicine 203 (4), 1021-1031, 2006 | 261 | 2006 |
Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division JT Chang, ML Ciocca, I Kinjyo, VR Palanivel, CE McClurkin, CS DeJong, ... Immunity 34 (4), 492-504, 2011 | 247 | 2011 |
Real-time tracking of cell cycle progression during CD8+ effector and memory T-cell differentiation I Kinjyo, J Qin, SY Tan, CJ Wellard, P Mrass, W Ritchie, A Doi, ... Nature communications 6, 6301, 2015 | 159 | 2015 |
Cyclic adenosine monophosphate suppresses the transcription of proinflammatory cytokines via the phosphorylated c-Fos protein K Koga, G Takaesu, R Yoshida, M Nakaya, T Kobayashi, I Kinjyo, ... Immunity 30 (3), 372-383, 2009 | 155 | 2009 |
SOCS3 is a physiological negative regulator for granulopoiesis and granulocyte colony-stimulating factor receptor signaling. A Kimura, I Kinjyo, Y Matsumura, H Mori, R Mashima, M Harada, ... Journal of Biological Chemistry 279 (8), 6905-6910, 2004 | 146 | 2004 |
Real‐time cell cycle imaging during melanoma growth, invasion, and drug response NK Haass, KA Beaumont, DS Hill, A Anfosso, P Mrass, MA Munoz, ... Pigment cell & melanoma research 27 (5), 764-776, 2014 | 137 | 2014 |
CD44 mediates successful interstitial navigation by killer T cells and enables efficient antitumor immunity P Mrass, I Kinjyo, LG Ng, SL Reiner, E Puré, W Weninger Immunity 29 (6), 971-985, 2008 | 106 | 2008 |
A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box. T Hanada, T Yoshida, I Kinjyo, S Minoguchi, H Yasukawa, S Kato, ... Journal of Biological Chemistry 276 (44), 40746-40754, 2001 | 90 | 2001 |
Analysis of SOCS-3 promoter responses to interferon γ L Gatto, C Berlato, V Poli, S Tininini, I Kinjyo, A Yoshimura, MA Cassatella, ... Journal of Biological Chemistry 279 (14), 13746-13754, 2004 | 88 | 2004 |
Silencing of SOCS1 in macrophages suppresses tumor development by enhancing antitumor inflammation M Hashimoto, T Ayada, I Kinjyo, K Hiwatashi, H Yoshida, Y Okada, ... Cancer science 100 (4), 730-736, 2009 | 78 | 2009 |
The neuropeptide neuromedin U activates eosinophils and is involved in allergen-induced eosinophilia M Moriyama, S Fukuyama, H Inoue, T Matsumoto, T Sato, K Tanaka, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 290 (5 …, 2006 | 71 | 2006 |
Negative regulation of cytokine signaling by CIS/SOCS family proteins and their roles in inflammatory diseases T Hanada, I Kinjyo, K Inagaki-Ohara, A Yoshimura Reviews of physiology, biochemistry and pharmacology, 72-86, 2003 | 53 | 2003 |
The janus kinase inhibitor, Jab/SOCS-1, is an interferon-γ inducible gene and determines the sensitivity to interferons H Sakamoto, I Kinjyo, A Yoshimura Leukemia & lymphoma 38 (1-2), 49-58, 2000 | 50 | 2000 |