Self-assembling protein microarrays N Ramachandran, E Hainsworth, B Bhullar, S Eisenstein, B Rosen, ... Science 305 (5680), 86-90, 2004 | 745 | 2004 |
Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision AY Lau, OD Schärer, L Samson, GL Verdine, T Ellenberger Cell 95 (2), 249-258, 1998 | 357 | 1998 |
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG AY Lau, MD Wyatt, BJ Glassner, LD Samson, T Ellenberger Proceedings of the National Academy of Sciences 97 (25), 13573-13578, 2000 | 289 | 2000 |
3‐methyladenine DNA glycosylases: structure, function, and biological importance MD Wyatt, JM Allan, AY Lau, TE Ellenberger, LD Samson Bioessays 21 (8), 668-676, 1999 | 257 | 1999 |
Nucleic-acid programmable protein arrays J Labaer, A Lau US Patent 6,800,453, 2004 | 205 | 2004 |
Nucleic-acid programmable protein arrays J Labaer, AY Lau US Patent 8,609,344, 2013 | 174 | 2013 |
Detection of protein folding defects caused by BRCA1-BRCT truncation and missense mutations RS Williams, DI Chasman, DD Hau, B Hui, AY Lau, JNM Glover Journal of Biological Chemistry 278 (52), 53007-53016, 2003 | 157 | 2003 |
The free energy landscapes governing conformational changes in a glutamate receptor ligand-binding domain AY Lau, B Roux Structure 15 (10), 1203-1214, 2007 | 125 | 2007 |
The hidden energetics of ligand-binding and activation in a glutamate receptor AY Lau, L Blachowicz, B Roux Biophysical Journal 100 (3), 268a, 2011 | 123 | 2011 |
Conformational analysis of NMDA receptor GluN1, GluN2, and GluN3 ligand-binding domains reveals subtype-specific characteristics Y Yao, J Belcher, AJ Berger, ML Mayer, AY Lau Structure 21 (10), 1788-1799, 2013 | 115 | 2013 |
Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR R Numano, S Szobota, AY Lau, P Gorostiza, M Volgraf, B Roux, ... Proceedings of the National Academy of Sciences 106 (16), 6814-6819, 2009 | 97 | 2009 |
Structural studies of human alkyladenine glycosylase and E. coli 3-methyladenine glycosylase T Hollis, A Lau, T Ellenberger Mutation Research/DNA Repair 460 (3-4), 201-210, 2000 | 83 | 2000 |
Base excision and DNA binding activities of human alkyladenine DNA glycosylase are sensitive to the base paired with a lesion CW Abner, AY Lau, T Ellenberger, LB Bloom Journal of Biological Chemistry 276 (16), 13379-13387, 2001 | 78 | 2001 |
Glutamate and glycine binding to the NMDA receptor A Yu, AY Lau Structure 26 (7), 1035-1043. e2, 2018 | 61 | 2018 |
A conformational intermediate in glutamate receptor activation AY Lau, H Salazar, L Blachowicz, V Ghisi, AJR Plested, B Roux Neuron 79 (3), 492-503, 2013 | 51 | 2013 |
A structural model for K2P potassium channels based on 23 pairs of interacting sites and continuum electrostatics A Kollewe, AY Lau, A Sullivan, B Roux, SAN Goldstein Journal of General Physiology 134 (1), 53-68, 2009 | 51 | 2009 |
Computing conformational free energy by deactivated morphing S Park, AY Lau, B Roux The Journal of chemical physics 129 (13), 2008 | 33 | 2008 |
Crystallizing thoughts about DNA base excision repair T Hollis, A Lau, T Ellenberger Progress in Nucleic Acid Research and Molecular Biology 68, 305-314, 2001 | 33 | 2001 |
Molecular lock regulates binding of glycine to a primitive NMDA receptor A Yu, R Alberstein, A Thomas, A Zimmet, R Grey, ML Mayer, AY Lau Proceedings of the National Academy of Sciences 113 (44), E6786-E6795, 2016 | 31 | 2016 |
Functional classification of proteins and protein variants AY Lau, DI Chasman Proceedings of the National Academy of Sciences 101 (17), 6576-6581, 2004 | 27 | 2004 |