Crystal structures of the human RNA demethylase Alkbh5 reveal basis for substrate recognition C Feng, Y Liu, G Wang, Z Deng, Q Zhang, W Wu, Y Tong, C Cheng, ... Journal of Biological Chemistry 289 (17), 11571-11583, 2014 | 180 | 2014 |
Mechanistic insights into metal ion activation and operator recognition by the ferric uptake regulator Z Deng, Q Wang, Z Liu, M Zhang, ACD Machado, TP Chiu, C Feng, ... Nature communications 6 (1), 1-12, 2015 | 117 | 2015 |
RNA exploits an exposed regulatory site to inhibit the enzymatic activity of PRC2 Q Zhang, NJ McKenzie, R Warneford-Thomson, EH Gail, SF Flanigan, ... Nature structural & molecular biology 26 (3), 237-247, 2019 | 98 | 2019 |
Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation J Zheng, Y Lang, Q Zhang, D Cui, H Sun, L Jiang, Z Chen, R Zhang, ... Genes & development 29 (14), 1524-1534, 2015 | 95 | 2015 |
Complex structures of the abscisic acid receptor PYL3/RCAR13 reveal a unique regulatory mechanism X Zhang, Q Zhang, Q Xin, L Yu, Z Wang, W Wu, L Jiang, G Wang, W Tian, ... Structure 20 (5), 780-790, 2012 | 90 | 2012 |
Structural insights into a novel histone demethylase PHF8 L Yu, Y Wang, S Huang, J Wang, Z Deng, Q Zhang, W Wu, X Zhang, Z Liu, ... Cell research 20 (2), 166-173, 2010 | 80 | 2010 |
Structure-function analysis reveals a novel mechanism for regulation of histone demethylase LSD2/AOF1/KDM1b Q Zhang, S Qi, M Xu, L Yu, Y Tao, Z Deng, W Wu, J Li, Z Chen, J Wong Cell research 23 (2), 225-241, 2013 | 77 | 2013 |
Structural insights into the abscisic acid stereospecificity by the ABA receptors PYR/PYL/RCAR X Zhang, L Jiang, G Wang, L Yu, Q Zhang, Q Xin, W Wu, Z Gong, Z Chen PLoS One 8 (7), e67477, 2013 | 63 | 2013 |
Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase Z Deng, KC Lehmann, X Li, C Feng, G Wang, Q Zhang, X Qi, L Yu, ... Nucleic acids research 42 (5), 3464-3477, 2014 | 60 | 2014 |
Family-wide characterization of histone binding abilities of human CW domain-containing proteins Y Liu, W Tempel, Q Zhang, X Liang, P Loppnau, S Qin, J Min Journal of Biological Chemistry 291 (17), 9000-9013, 2016 | 54 | 2016 |
Crystal structure and activity-based labeling reveal the mechanisms for linkage-specific substrate recognition by deubiquitinase USP9X P Paudel, Q Zhang, C Leung, HC Greenberg, Y Guo, YH Chern, A Dong, ... Proceedings of the National Academy of Sciences 116 (15), 7288-7297, 2019 | 51 | 2019 |
New insights into the RNA-binding and E3 ubiquitin ligase activities of roquins Q Zhang, L Fan, F Hou, A Dong, YX Wang, Y Tong Scientific reports 5 (1), 1-13, 2015 | 37 | 2015 |
PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis Q Zhang, SC Agius, SF Flanigan, M Uckelmann, V Levina, BM Owen, ... Nature communications 12 (1), 1-18, 2021 | 35* | 2021 |
Structural basis of the recruitment of ubiquitin-specific protease USP15 by spliceosome recycling factor SART3 Q Zhang, R Harding, F Hou, A Dong, JR Walker, J Bteich, Y Tong Journal of Biological Chemistry 291 (33), 17283-17292, 2016 | 31 | 2016 |
The substrate binding domains of human SIAH E3 ubiquitin ligases are now crystal clear Q Zhang, Z Wang, F Hou, R Harding, X Huang, A Dong, JR Walker, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (1), 3095-3105, 2017 | 30 | 2017 |
Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation Y Gao, Q Zhang, Y Lang, Y Liu, X Dong, Z Chen, W Tian, J Tang, W Wu, ... Journal of molecular cell biology 9 (3), 220-230, 2017 | 16 | 2017 |
Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1 Y Guo, Q Liu, E Mallette, C Caba, F Hou, J Fux, G LaPlante, A Dong, ... Journal of Biological Chemistry 297 (4), 2021 | 13 | 2021 |
The apparent loss of PRC2 chromatin occupancy as an artefact of RNA depletion E Healy, Q Zhang, EH Gail, SC Agius, G Sun, M Bullen, V Pandey, ... Cell Reports, 2024.113858, 2024 | 12 | 2024 |
Dominant negative and directional dysregulation of Polycomb function in EZH2-mutant human growth disorders O Deevy, C Monger, F Matra, E Tuck, E Conway, S Rodighiero, Q Zhang, ... bioRxiv, 2023.06. 01.543208, 2023 | 3 | 2023 |
Allosteric regulation of histone lysine methyltransferases: from context-specific regulation to selective drugs C Davidovich, Q Zhang Biochemical Society Transactions 49 (2), 591-607, 2021 | 3 | 2021 |