DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1 HC Hemmings Jr, P Greengard, HYL Tung, P Cohen Nature 310 (5977), 503-505, 1984 | 765 | 1984 |
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons DJ Surmeier, J Bargas, HC Hemmings Jr, AC Nairn, P Greengard Neuron 14 (2), 385-397, 1995 | 696 | 1995 |
DARPP-32, a dopamine-and adenosine 3': 5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. III. Immunocytochemical localization CC Ouimet, PE Miller, HC Hemmings, SI Walaas, P Greengard Journal of Neuroscience 4 (1), 111-124, 1984 | 694 | 1984 |
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons JA Bibb, GL Snyder, A Nishi, Z Yan, L Meijer, AA Fienberg, LH Tsai, ... Nature 402 (6762), 669-671, 1999 | 668 | 1999 |
Protein kinases in the brain AC Naira, HC Hemmings Jr, P Greengard Annual review of biochemistry 54 (1), 931-976, 1985 | 637 | 1985 |
Emerging molecular mechanisms of general anesthetic action HC Hemmings, MH Akabas, PA Goldstein, JR Trudell, BA Orser, ... Trends in pharmacological sciences 26 (10), 503-510, 2005 | 607 | 2005 |
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar V Jevtovic-Todorovic, AR Absalom, K Blomgren, A Brambrink, G Crosby, ... British journal of anaesthesia 111 (2), 143-151, 2013 | 300 | 2013 |
The hypothalamic arcuate nucleus-median eminence complex: immunohistochemistry of transmitters, peptides and DARPP-32 with special reference to coexistence in dopamine neurons BJ Everitt, B Meister, T Hökfelt, T Melander, L Terenius, Å Rökaeus, ... Brain Research Reviews 11 (2), 97-155, 1986 | 282 | 1986 |
Phytochemicals perturb membranes and promiscuously alter protein function HI Ingólfsson, P Thakur, KF Herold, EA Hobart, NB Ramsey, X Periole, ... ACS chemical biology 9 (8), 1788-1798, 2014 | 280 | 2014 |
Are anaesthetics toxic to the brain? AE Hudson, HC Hemmings Jr British journal of anaesthesia 107 (1), 30-37, 2011 | 261 | 2011 |
DARPP-32, a dopamine-and adenosine 3': 5'-monophosphate-regulated phosphoprotein: regional, tissue, and phylogenetic distribution HC Hemmings, P Greengard Journal of Neuroscience 6 (5), 1469-1481, 1986 | 251 | 1986 |
DARPP-32, a dopamine-and adenosine 3': 5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. II. Purification and characterization of the … HC Hemmings, AC Nairn, DW Aswad, P Greengard Journal of Neuroscience 4 (1), 99-110, 1984 | 246 | 1984 |
Role of protein phosphorylation in neuronal signal transduction1 HC Hemmings Jr, AC Nairn, TL McGuinness, RL Huganir, P Greengard The FASEB journal 3 (5), 1583-1592, 1989 | 245 | 1989 |
Mammalian brain phosphoproteins as substrates for calcineurin. MM King, CY Huang, PB Chock, AC Nairn, HC Hemmings, KF Chan, ... Journal of Biological Chemistry 259 (13), 8080-8083, 1984 | 243 | 1984 |
Opposing changes in phosphorylation of specific sites in synapsin I during Ca2+-dependent glutamate release in isolated nerve terminals JN Jovanovic, TS Sihra, AC Nairn, HC Hemmings, P Greengard, ... Journal of Neuroscience 21 (20), 7944-7953, 2001 | 225 | 2001 |
Evidence for decreased DARPP-32 in the prefrontal cortex of patients with schizophrenia KA Albert, HC Hemmings, AIB Adamo, SG Potkin, S Akbarian, ... Archives of general psychiatry 59 (8), 705-712, 2002 | 203 | 2002 |
Phosphorylation of DARPP-32, a dopamine-and cAMP-regulated phosphoprotein, by casein kinase II JA Girault, HC Hemmings, KR Williams, AC Nairn, P Greengard Journal of Biological Chemistry 264 (36), 21748-21759, 1989 | 194 | 1989 |
Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+, K (+)-ATPase and effects of site-directed mutagenesis. G Fisone, SX Cheng, AC Nairn, AJ Czernik, HC Hemmings Jr, JO Höög, ... Journal of Biological Chemistry 269 (12), 9368-9373, 1994 | 186 | 1994 |
Towards a comprehensive understanding of anesthetic mechanisms of action: a decade of discovery HC Hemmings, PM Riegelhaupt, MB Kelz, K Solt, RG Eckenhoff, BA Orser, ... Trends in pharmacological sciences 40 (7), 464-481, 2019 | 182 | 2019 |
DARPP-32, a dopamine-and adenosine 3 ‘: 5 ‘-monophosphate-regulated neuronal phosphoprotein. II. Comparison of the kinetics of phosphorylation of DARPP-32 and phosphatase … HC Hemmings Jr, AC Nairn, P Greengard Journal of Biological Chemistry 259 (23), 14491-14497, 1984 | 173 | 1984 |