关注
Charles J. Eyermann
Charles J. Eyermann
Northeastern University
在 northeastern.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors
PYS Lam, PK Jadhav, CJ Eyermann, CN Hodge, Y Ru, LT Bacheler, ...
Science 263 (5145), 380-384, 1994
11571994
Core-electron binding energies for gaseous atoms and molecules
WL Jolly, KD Bomben, CJ Eyermann
Atomic Data and Nuclear Data Tables 31 (3), 433-493, 1984
4461984
Identification of 4-substituted 1, 2, 3-triazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase A
F Reck, F Zhou, M Girardot, G Kern, CJ Eyermann, NJ Hales, RR Ramsay, ...
Journal of medicinal chemistry 48 (2), 499-506, 2005
3552005
Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2 ‘structure− activity relationship, and molecular recognition of cyclic ureas
PYS Lam, Y Ru, PK Jadhav, PE Aldrich, GV DeLucca, CJ Eyermann, ...
Journal of medicinal chemistry 39 (18), 3514-3525, 1996
2581996
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell stem cell 29 (2), 217-231. e8, 2022
1892022
Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450
CN Hodge, PE Aldrich, LT Bacheler, CH Chang, CJ Eyermann, S Garber, ...
Chemistry & biology 3 (4), 301-314, 1996
1781996
NMR and X-ray evidence that the HIV protease catalytic aspartyl groups are protonated in the complex formed by the protease and a non-peptide cyclic urea-based inhibitor
T Yamazaki, LK Nicholson, P Wingfield, SJ Stahl, JD Kaufman, ...
Journal of the American Chemical Society 116 (23), 10791-10792, 1994
1691994
Structural studies of a family of high affinity ligands for GPIIb/IIIa
AC Bach, CJ Eyermann, JD Gross, MJ Bower, RL Harlow, PC Weber, ...
Journal of the American Chemical Society 116 (8), 3207-3219, 1994
1461994
Discovery of potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70
CB Vu, EG Corpuz, TJ Merry, SG Pradeepan, C Bartlett, RS Bohacek, ...
Journal of medicinal chemistry 42 (20), 4088-4098, 1999
1281999
Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II: broad-spectrum antibacterial agents with reduced hERG activity
F Reck, R Alm, P Brassil, J Newman, B DeJonge, CJ Eyermann, G Breault, ...
Journal of medicinal chemistry 54 (22), 7834-7847, 2011
1162011
NMR evidence for the displacement of a conserved interior water molecule in HIV protease by a non-peptide cyclic urea-based inhibitor
S Grzesiek, A Bax, LK Nicholson, T Yamazaki, P Wingfield, SJ Stahl, ...
Journal of the American Chemical Society 116 (4), 1581-1582, 1994
801994
Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
PYS Lam, PK Jadhav, CJ Eyermann, CN Hodge, GV De Lucca, ...
US Patent 5,811,422, 1998
791998
Molecular recognition of cyclic urea HIV-1 protease inhibitors
PJ Ala, RJ DeLoskey, EE Huston, PK Jadhav, PYS Lam, CJ Eyermann, ...
Journal of Biological Chemistry 273 (20), 12325-12331, 1998
761998
SRC homology-2 inhibitors: peptidomimetic and nonpeptide
TK Sawyer, RS Bohacek, DC Dalgarno, CJ Eyermann, N Kawahata, ...
Mini reviews in medicinal chemistry 2 (5), 475-488, 2002
752002
Nonpeptide cyclic cyanoguanidines as HIV-1 protease inhibitors: synthesis, structure− activity relationships, and X-ray crystal structure studies
PK Jadhav, FJ Woerner, PYS Lam, CN Hodge, CJ Eyermann, HW Man, ...
Journal of medicinal chemistry 41 (9), 1446-1455, 1998
681998
Transformations of resin-bound pyridinium ylides: I. A stereoselective synthesis of 2, 2, 3-trisubstituted cyclopropanecarboxylates
NH Vo, CJ Eyermann, CN Hodge
Tetrahedron letters 38 (46), 7951-7954, 1997
651997
Plasmodial kinase inhibitors: license to cure?
DG Cabrera, A Horatscheck, CR Wilson, G Basarab, CJ Eyermann, ...
Journal of Medicinal Chemistry 61 (18), 8061-8077, 2018
572018
Calculated and experimental low-energy conformations of cyclic urea HIV protease inhibitors
CN Hodge, PYS Lam, CJ Eyermann, PK Jadhav, Y Ru, CH Fernandez, ...
Journal of the American Chemical Society 120 (19), 4570-4581, 1998
571998
Novel substituted (pyridin-3-yl) phenyloxazolidinones: antibacterial agents with reduced activity against monoamine oxidase A and increased solubility
F Reck, F Zhou, CJ Eyermann, G Kern, D Carcanague, G Ioannidis, ...
Journal of medicinal chemistry 50 (20), 4868-4881, 2007
552007
Potent and selective inhibitors of Helicobacter pylori glutamate racemase (MurI): Pyridodiazepine amines
B Geng, G Basarab, J Comita-Prevoir, M Gowravaram, P Hill, A Kiely, ...
Bioorganic & medicinal chemistry letters 19 (3), 930-936, 2009
522009
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