| Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ... Neuron 84 (6), 1213-1225, 2014 | 584 | 2014 |
| Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 579 | 2018 |
| Cell-to-cell transmission of dipeptide repeat proteins linked to C9orf72-ALS/FTD T Westergard, BK Jensen, X Wen, J Cai, E Kropf, L Iacovitti, P Pasinelli, ... Cell reports 17 (3), 645-652, 2016 | 231 | 2016 |
| Repeat‐associated non‐AUG translation in C9orf72‐ALS/FTD is driven by neuronal excitation and stress T Westergard, K McAvoy, K Russell, X Wen, Y Pang, B Morris, P Pasinelli, ... EMBO molecular medicine 11 (2), e9423, 2019 | 115 | 2019 |
| Pathogenic determinants and mechanisms of ALS/FTD linked to hexanucleotide repeat expansions in the C9orf72 gene X Wen, T Westergard, P Pasinelli, D Trotti Neuroscience letters 636, 16-26, 2017 | 53 | 2017 |
| Synaptic dysfunction induced by glycine‐alanine dipeptides in C9orf72‐ALS/FTD is rescued by SV 2 replenishment BK Jensen, MH Schuldi, K McAvoy, KA Russell, A Boehringer, BM Curran, ... EMBO molecular medicine 12 (5), e10722, 2020 | 46 | 2020 |
| A mouse model with widespread expression of the C9orf72-linked glycine–arginine dipeptide displays non-lethal ALS/FTD-like phenotypes BM Verdone, ME Cicardi, X Wen, S Sriramoji, K Russell, SS Markandaiah, ... Scientific reports 12 (1), 5644, 2022 | 20 | 2022 |
| Cell-to-cell transmission of dipeptide repeat proteins linked to C9orf72-ALS/FTD. Cell Rep 17: 645–652 T Westergard, BK Jensen, X Wen, J Cai, E Kropf, L Iacovitti, P Pasinelli, ... | 13 | 2016 |
| Antisense proline-arginine RAN dipeptides linked to X Wen, W Tan, T Westergard, K Krishnamurthy, SS Markandaiah, Y Shi, ... C9ORF72, 0 | 11 | |
| Aberrant expression of the axon guidance cue netrin-1 by SOD1-ALS astrocytes contributes to motor neuron degeneration. K Krishnamurthy, S Markandaiah, M Cicardi, B Ghosh, X Wen, K McAvoy, ... GLIA 69, E194-E194, 2021 | | 2021 |
| Identification of Pathogenic Determinants and Mechanisms of C9ORF72 linked ALS/FTD X Wen Thomas Jefferson University, 2016 | | 2016 |
| Aberrant secretion of netrin-1 from astrocytes is toxic to motor neurons in a mouse model of amyotrophic lateral sclerosis A Bogush, E Foran, X Wen, L Rosenblum, A Kia, W Tan, P Pasinelli, ... Implication of a sumoylated c-terminal fragment of the astroglial glutamate …, 2013 | | 2013 |
| Let us know how access to this document benefits yo u T Westergard, BK Jensen, X Wen, J Cai Cell 10, 11-2016, 0 | | |
