Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder J Groet, S McElwaine, M Spinelli, A Rinaldi, I Burtscher, C Mulligan, ... The Lancet 361 (9369), 1617-1620, 2003 | 249 | 2003 |
Development and clinical translation of approved gene therapy products for genetic disorders A Shahryari, M Saghaeian Jazi, S Mohammadi, H Razavi Nikoo, Z Nazari, ... Frontiers in genetics 10, 868, 2019 | 236 | 2019 |
Foxa2 regulates polarity and epithelialization in the endoderm germ layer of the mouse embryo I Burtscher, H Lickert Oxford University Press for The Company of Biologists Limited 136 (6), 1029-1038, 2009 | 233 | 2009 |
Early myeloid lineage choice is not initiated by random PU. 1 to GATA1 protein ratios PS Hoppe, M Schwarzfischer, D Loeffler, KD Kokkaliaris, O Hilsenbeck, ... Nature 535 (7611), 299-302, 2016 | 227 | 2016 |
Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis A Bastidas-Ponce, S Tritschler, L Dony, K Scheibner, M Tarquis-Medina, ... Development 146 (12), dev173849, 2019 | 199 | 2019 |
Pitchfork regulates primary cilia disassembly and left-right asymmetry D Kinzel, K Boldt, EE Davis, I Burtscher, D Trümbach, B Diplas, ... Developmental cell 19 (1), 66-77, 2010 | 168 | 2010 |
Wnt/β-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse S Engert, I Burtscher, WP Liao, S Dulev, G Schotta, H Lickert Development 140 (15), 3128-3138, 2013 | 120 | 2013 |
Foxa2 identifies a cardiac progenitor population with ventricular differentiation potential E Bardot, D Calderon, F Santoriello, S Han, K Cheung, B Jadhav, ... Nature communications 8 (1), 14428, 2017 | 99 | 2017 |
Foxa2 and Pdx1 cooperatively regulate postnatal maturation of pancreatic β-cells A Bastidas-Ponce, SS Roscioni, I Burtscher, E Bader, M Sterr, M Bakhti, ... Molecular metabolism 6 (6), 524-534, 2017 | 89 | 2017 |
Genome-wide analysis of PDX1 target genes in human pancreatic progenitors X Wang, M Sterr, I Burtscher, S Chen, A Hieronimus, F Machicao, ... Molecular metabolism 9, 57-68, 2018 | 87 | 2018 |
Genetic ablation of FLRT3 reveals a novel morphogenetic function for the anterior visceral endoderm in suppressing mesoderm differentiation J Egea, C Erlacher, E Montanez, I Burtscher, S Yamagishi, M Heß, ... Genes & development 22 (23), 3349-3362, 2008 | 78 | 2008 |
Point mutations in the PDX1 transactivation domain impair human β-cell development and function X Wang, M Sterr, I Burtscher, A Böttcher, J Beckenbauer, J Siehler, ... Molecular metabolism 24, 80-97, 2019 | 76 | 2019 |
Sox17‐2A‐iCre: A knock‐in mouse line expressing Cre recombinase in endoderm and vascular endothelial cells S Engert, WP Liao, I Burtscher, H Lickert Genesis 47 (9), 603-610, 2009 | 76 | 2009 |
Pre-marked chromatin and transcription factor co-binding shape the pioneering activity of Foxa2 FM Cernilogar, S Hasenöder, Z Wang, K Scheibner, I Burtscher, M Sterr, ... Nucleic Acids Research 47 (17), 9069-9086, 2019 | 72 | 2019 |
Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates A Böttcher, M Büttner, S Tritschler, M Sterr, A Aliluev, L Oppenländer, ... Nature cell biology 23 (1), 23-31, 2021 | 66 | 2021 |
Engineering gene therapy: advances and barriers A Shahryari, I Burtscher, Z Nazari, H Lickert Advanced Therapeutics 4 (9), 2100040, 2021 | 60 | 2021 |
Generation of a mouse line expressing Sox17‐driven Cre recombinase with specific activity in arteries WP Liao, L Uetzmann, I Burtscher, H Lickert Genesis 47 (7), 476-483, 2009 | 57 | 2009 |
Epithelial cell plasticity drives endoderm formation during gastrulation K Scheibner, S Schirge, I Burtscher, M Büttner, M Sterr, D Yang, ... Nature cell biology 23 (7), 692-703, 2021 | 56 | 2021 |
Flattop regulates basal body docking and positioning in mono-and multiciliated cells M Gegg, A Böttcher, I Burtscher, S Hasenoeder, C Van Campenhout, ... Elife 3, e03842, 2014 | 52 | 2014 |
A mouse line expressing Foxa2‐driven Cre recombinase in node, notochord, floorplate, and endoderm L Uetzmann, I Burtscher, H Lickert Genesis 46 (10), 515-522, 2008 | 46 | 2008 |