Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making A Paini, JA Leonard, E Joossens, JGM Bessems, A Desalegn, JL Dorne, ... Computational Toxicology 9, 61-72, 2019 | 123 | 2019 |
Effective exposure of chemicals in in vitro cell systems: A review of chemical distribution models S Proença, BI Escher, FC Fischer, C Fisher, S Grégoire, NJ Hewitt, B Nicol, ... Toxicology in Vitro 73, 105133, 2021 | 77 | 2021 |
Insights into in vitro biokinetics using Virtual Cell Based Assay simulations S Proença, A Paini, E Joossens, JVS Benito, E Berggren, A Worth, ... ALTEX-Alternatives to animal experimentation 36 (3), 447-461, 2019 | 15 | 2019 |
EURL ECVAM Workshop on new generation of physiologically-based kinetic models in risk assessment A Paini, E Joossens, J Bessems, A Desalegn, JL Dorne, JP Gosling, ... Publications Office of the European Union, 2017 | 13 | 2017 |
Insights into PCDD/Fs and PAHs in biomass boilers envisaging risks of ash use as fertilizers H Lopes, S Proença Applied Sciences 10 (14), 4951, 2020 | 11 | 2020 |
Drug metabolism of hepatocyte-like organoids and their applicability in in vitro toxicity testing MC Bouwmeester, Y Tao, S Proença, FG van Steenbeek, RA Samsom, ... Molecules 28 (2), 621, 2023 | 8 | 2023 |
HiPSC-derived hepatocyte-like cells can be used as a model for Transcriptomics-based study of chemical toxicity S Ghosh, J De Smedt, T Tricot, S Proença, M Kumar, F Nami, ... Toxics 10 (1), 1, 2021 | 7 | 2021 |
Pyridine-containing macrocycles display MMP-2/9 inhibitory activity and distinct effects on migration and invasion of 2D and 3D breast cancer models S Proença, B Antunes, RC Guedes, F Ramilo-Gomes, MF Cabral, J Costa, ... International Journal of Molecular Sciences 20 (20), 5109, 2019 | 6 | 2019 |
Effective Exposure of Chemicals in S Proença, BI Escher, FC Fischer, C Fisher, S Grégoire, NJ Hewitt Vitro, 2021 | 5 | 2021 |
Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making. Computational toxicology (Amsterdam, Netherlands) 9, 61–72 A Paini, JA Leonard, E Joossens, J Bessems, A Desalegn, JL Dorne, ... | 5 | 2019 |
Impact of the SOD mimic MnTnHex-2-PyP on the adhesion and migration of doxorubicin-treated MDA-MB-231 cells A Florido, N Saraiva, S Cerqueira, I Batinic-Haberle, S Proença, ... Toxicology Letters 2 (238), S241-S242, 2015 | 4 | 2015 |
EURL ECVAM workshop on new generation of physiologically-based kinetic models in risk assessment (2017) A Paini, E Joossens, J Bessems, A Desalegn, JL Dorne, JP Gosling, ... | 3 | |
Integrating distribution kinetics and toxicodynamics to assess repeat dose neurotoxicity in vitro using human BrainSpheres: a case study on amiodarone C Nunes, S Proença, G Ambrosini, D Pamies, A Thomas, NI Kramer, ... Frontiers in Pharmacology 14, 1248882, 2023 | 1 | 2023 |
The effects of hexabromocyclododecane on the transcriptome and hepatic enzyme activity in three human HepaRG-based models S Proença, N van Sabben, J Legler, JH Kamstra, NI Kramer Toxicology 485, 153411, 2023 | 1 | 2023 |
Application of the Virtual Cell Based Assay for Simulation of in vitro Chemical fate following Acute Exposure S Proenca, A Paini, E Joossens, JV Sala Benito, E Berggren, A Worth, ... JRC technical reports, European Union, 2017 | 1 | 2017 |
Development of a test battery for the detection of induction of molecular initiating events of cholestatic liver toxicity induced by chemical compounds J Sanz-Serrano, E Benfenati, AH Drees, D Gadaleta, MG de Lomana, ... 3rd Annual ONTOX Meeting, 2024 | | 2024 |
Distribution Kinetics of Triazole Fungicides in an In Vitro Liver Steatosis Model S Adam, M Anagnostaki, W Bakker, S Proença, A Sotiriou, A Verhoeven, ... EUROTOX 2024: Toxicology–A Quest for safe Chemicals and Medicines, 2024 | | 2024 |
NAM to identify (low, medium, high) concern of carboxylic acid-induced hepatic steatosis R Jover, P Soluyanova, M del Pozo, A Verhoeven, T Vanhaecke, ... EPAA Designathon Workshop, 2024 | | 2024 |
Next Generation PBK modeling with PK-Sim for the prediction of chemical distribution in humans R Geci, D Gadaleta, S Proenca, E Colombo, MG de Lomana, ... TOXICOLOGY LETTERS 384, S70-S71, 2023 | | 2023 |
A qualified open-source framework for precision toxicology by integration of PBK with mechanism-based quantification of AOPs S Schaller, A Paini, P Balazki, R Geci, S Proenca, N Kramer, L Kuepfer, ... TOXICOLOGY LETTERS 384, S48-S48, 2023 | | 2023 |