Pan-cancer patterns of somatic copy number alteration TI Zack, SE Schumacher, SL Carter, AD Cherniack, G Saksena, B Tabak, ... Nature genetics 45 (10), 1134-1140, 2013 | 1960 | 2013 |
Chromothripsis from DNA damage in micronuclei CZ Zhang, A Spektor, H Cornils, JM Francis, EK Jackson, S Liu, ... Nature 522 (7555), 179-184, 2015 | 1160 | 2015 |
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors VA Adalsteinsson, G Ha, SS Freeman, AD Choudhury, DG Stover, ... Nature communications 8 (1), 1324, 2017 | 826 | 2017 |
Patterns of somatic structural variation in human cancer genomes Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ... Nature 578 (7793), 112-121, 2020 | 745 | 2020 |
Genomic copy number dictates a gene-independent cell response to CRISPR/Cas9 targeting AJ Aguirre, RM Meyers, BA Weir, F Vazquez, CZ Zhang, U Ben-David, ... Cancer discovery 6 (8), 914-929, 2016 | 667 | 2016 |
Mechanoenzymatic cleavage of the ultralarge vascular protein von Willebrand factor X Zhang, K Halvorsen, CZ Zhang, WP Wong, TA Springer Science 324 (5932), 1330-1334, 2009 | 619 | 2009 |
Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer JG Lohr, VA Adalsteinsson, K Cibulskis, AD Choudhury, M Rosenberg, ... Nature biotechnology 32 (5), 479-484, 2014 | 614 | 2014 |
Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces J Zhu, BH Luo, T Xiao, C Zhang, N Nishida, TA Springer Molecular cell 32 (6), 849-861, 2008 | 601 | 2008 |
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing I Cortés-Ciriano, JJK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ... Nature genetics 52 (3), 331-341, 2020 | 575 | 2020 |
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ... Nature 578 (7793), 102-111, 2020 | 537 | 2020 |
Chromothripsis as an on-target consequence of CRISPR–Cas9 genome editing ML Leibowitz, S Papathanasiou, PA Doerfler, LJ Blaine, L Sun, Y Yao, ... Nature Genetics 53 (6), 895-905, 2021 | 430 | 2021 |
Mechanisms generating cancer genome complexity from a single cell division error NT Umbreit, CZ Zhang, LD Lynch, LJ Blaine, AM Cheng, R Tourdot, L Sun, ... Science 368 (6488), eaba0712, 2020 | 370 | 2020 |
SvABA: genome-wide detection of structural variants and indels by local assembly JA Wala, P Bandopadhayay, NF Greenwald, R O'Rourke, T Sharpe, ... Genome research 28 (4), 581-591, 2018 | 353 | 2018 |
Breaching self-tolerance to Alu duplex RNA underlies MDA5-mediated inflammation S Ahmad, X Mu, F Yang, E Greenwald, JW Park, E Jacob, CZ Zhang, ... Cell 172 (4), 797-810. e13, 2018 | 353 | 2018 |
Structural alterations driving castration-resistant prostate cancer revealed by linked-read genome sequencing SR Viswanathan, G Ha, AM Hoff, JA Wala, J Carrot-Zhang, CW Whelan, ... Cell 174 (2), 433-447. e19, 2018 | 341 | 2018 |
A mechanically stabilized receptor-ligand flex-bond important in the vasculature J Kim, CZ Zhang, X Zhang, TA Springer Nature 466 (7309), 992-995, 2010 | 326 | 2010 |
EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing JM Francis, CZ Zhang, CL Maire, J Jung, VE Manzo, VA Adalsteinsson, ... Cancer discovery 4 (8), 956-971, 2014 | 312 | 2014 |
Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements CZ Zhang, ML Leibowitz, D Pellman Genes & development 27 (23), 2513-2530, 2013 | 262 | 2013 |
Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor Q Zhang, YF Zhou, CZ Zhang, X Zhang, C Lu, TA Springer Proceedings of the National Academy of Sciences 106 (23), 9226-9231, 2009 | 236 | 2009 |
Chromothripsis: A New Mechanism for Rapid Karyotype Evolution. ML Leibowitz, CZ Zhang, D Pellman Annual review of genetics 49, 183-211, 2015 | 204 | 2015 |