Inflammatory networks during cellular senescence: causes and consequences A Freund, AV Orjalo, PY Desprez, J Campisi Trends in molecular medicine 16 (5), 238-246, 2010 | 1523 | 2010 |
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation RM Laberge, YU Sun, AV Orjalo, CK Patil, A Freund, L Zhou, SC Curran, ... Nature cell biology 17 (8), 1049-1061, 2015 | 1024 | 2015 |
Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network AV Orjalo, D Bhaumik, BK Gengler, GK Scott, J Campisi Proceedings of the National Academy of Sciences 106 (40), 17031-17036, 2009 | 677 | 2009 |
MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8 D Bhaumik, GK Scott, S Schokrpur, CK Patil, AV Orjalo, F Rodier, ... Aging 1 (4), 402, 2009 | 568 | 2009 |
Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination JH Yoon, K Abdelmohsen, J Kim, X Yang, JL Martindale, ... Nature communications 4 (1), 2939, 2013 | 483 | 2013 |
Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores A Harel, AV Orjalo, T Vincent, A Lachish-Zalait, S Vasu, S Shah, ... Molecular cell 11 (4), 853-864, 2003 | 308 | 2003 |
ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division BA Rasala, AV Orjalo, Z Shen, S Briggs, DJ Forbes Proceedings of the National Academy of Sciences 103 (47), 17801-17806, 2006 | 292 | 2006 |
Depletion of cellular polyamines, spermidine and spermine, causes a total arrest in translation and growth in mammalian cells S Mandal, A Mandal, HE Johansson, AV Orjalo, MH Park Proceedings of the National Academy of Sciences 110 (6), 2169-2174, 2013 | 275 | 2013 |
Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export S Vasu, S Shah, A Orjalo, M Park, WH Fischer, DJ Forbes The Journal of cell biology 155 (3), 339-354, 2001 | 228 | 2001 |
The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly AV Orjalo, A Arnaoutov, Z Shen, Y Boyarchuk, SG Zeitlin, B Fontoura, ... Molecular biology of the cell 17 (9), 3806-3818, 2006 | 182 | 2006 |
HOTAIR and its surrogate DNA methylation signature indicate carboplatin resistance in ovarian cancer AE Teschendorff, SH Lee, A Jones, H Fiegl, M Kalwa, W Wagner, ... Genome medicine 7, 1-12, 2015 | 167 | 2015 |
Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype CD Wiley, N Schaum, F Alimirah, JA Lopez-Dominguez, AV Orjalo, ... Scientific reports 8 (1), 2410, 2018 | 114 | 2018 |
Transcriptional silencing of long noncoding RNA GNG12-AS1 uncouples its transcriptional and product-related functions L Stojic, M Niemczyk, A Orjalo, Y Ito, AEM Ruijter, S Uribe-Lewis, ... Nature communications 7 (1), 10406, 2016 | 86 | 2016 |
Coactivators enable glucocorticoid receptor recruitment to fine-tune estrogen receptor transcriptional responses MJ Bolt, F Stossi, JY Newberg, A Orjalo, HE Johansson, MA Mancini Nucleic acids research 41 (7), 4036-4048, 2013 | 61 | 2013 |
Stellaris™ fluorescence in situ hybridization (FISH) probes: a powerful tool for mRNA detection A Orjalo, HE Johansson, JL Ruth Nature methods 8 (10), i-ii, 2011 | 61 | 2011 |
Stellaris® RNA Fluorescence In Situ Hybridization for the Simultaneous Detection of Immature and Mature Long Noncoding RNAs in Adherent Cells AV Orjalo, HE Johansson Long Non-Coding RNAs: Methods and Protocols, 119-134, 2016 | 40 | 2016 |
Female bias in systemic lupus erythematosus is associated with the differential expression of X-linked toll-like receptor 8 G McDonald, N Cabal, A Vannier, B Umiker, RH Yin, AV Orjalo Jr, ... Frontiers in immunology 6, 457, 2015 | 38 | 2015 |
Simultaneous Detection of Nuclear and Cytoplasmic RNA Variants Utilizing Stellaris® RNA Fluorescence In Situ Hybridization in Adherent Cells SR Coassin, AV Orjalo, SJ Semaan, HE Johansson In Situ Hybridization Protocols, 189-199, 2014 | 32 | 2014 |
The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1/Hippo signaling pathway Q Hao, X Zong, Q Sun, YC Lin, YJ Song, S Hashemikhabir, RYC Hsu, ... Elife 9, e55102, 2020 | 28 | 2020 |
CD133 does not enrich for the stem cell activity in vivo in adult mouse prostates X Wei, AV Orjalo, L Xin Stem Cell Research 16 (3), 597-606, 2016 | 11 | 2016 |