Human β-defensins M Pazgier, DM Hoover, D Yang, W Lu, J Lubkowski Cellular and Molecular Life Sciences CMLS 63, 1294-1313, 2006 | 710 | 2006 |
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3 Z Wu, DM Hoover, D Yang, C Boulegue, F Santamaria, JJ Oppenheim, ... Proceedings of the National Academy of Sciences 100 (15), 8880-8885, 2003 | 528 | 2003 |
α‐Defensins in human innate immunity RI Lehrer, W Lu Immunological reviews 245 (1), 84-112, 2012 | 494 | 2012 |
Structural basis for high-affinity peptide inhibition of p53 interactions with MDM2 and MDMX M Pazgier, M Liu, G Zou, W Yuan, C Li, C Li, J Li, J Monbo, D Zella, ... Proceedings of the National Academy of Sciences 106 (12), 4665-4670, 2009 | 420 | 2009 |
Human α-defensin 6 promotes mucosal innate immunity through self-assembled peptide nanonets H Chu, M Pazgier, G Jung, SP Nuccio, PA Castillo, MF De Jong, ... Science 337 (6093), 477-481, 2012 | 418 | 2012 |
Antibacterial activity and specificity of the six human α-defensins B Ericksen, Z Wu, W Lu, RI Lehrer Antimicrobial agents and chemotherapy 49 (1), 269-275, 2005 | 398 | 2005 |
Human α-and β-defensins block multiple steps in herpes simplex virus infection E Hazrati, B Galen, W Lu, W Wang, Y Ouyang, MJ Keller, RI Lehrer, ... The Journal of Immunology 177 (12), 8658-8666, 2006 | 339 | 2006 |
Human α-defensins block papillomavirus infection CB Buck, PM Day, CD Thompson, J Lubkowski, W Lu, DR Lowy, ... Proceedings of the National Academy of Sciences 103 (5), 1516-1521, 2006 | 329 | 2006 |
Human β-defensins suppress human immunodeficiency virus infection: potential role in mucosal protection L Sun, CM Finnegan, T Kish-Catalone, R Blumenthal, P Garzino-Demo, ... Journal of virology 79 (22), 14318-14329, 2005 | 329 | 2005 |
Antimicrobial characterization of human β-defensin 3 derivatives DM Hoover, Z Wu, K Tucker, W Lu, J Lubkowski Antimicrobial agents and chemotherapy 47 (9), 2804-2809, 2003 | 317 | 2003 |
The structure of human macrophage inflammatory protein-3α/CCL20: linking antimicrobial and cc chemokine receptor-6-binding activities with human β-defensins DM Hoover, C Boulegue, D Yang, JJ Oppenheim, K Tucker, W Lu, ... Journal of Biological Chemistry 277 (40), 37647-37654, 2002 | 314 | 2002 |
Crystal structures of human α‐defensins HNP4, HD5, and HD6 A Szyk, Z Wu, K Tucker, D Yang, W Lu, J Lubkowski Protein Science 15 (12), 2749-2760, 2006 | 247 | 2006 |
D-peptide inhibitors of the p53–MDM2 interaction for targeted molecular therapy of malignant neoplasms M Liu, C Li, M Pazgier, C Li, Y Mao, Y Lv, B Gu, G Wei, W Yuan, C Zhan, ... Proceedings of the National Academy of Sciences 107 (32), 14321-14326, 2010 | 241 | 2010 |
Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II E de Leeuw, C Li, P Zeng, C Li, M Diepeveen-de Buin, WY Lu, E Breukink, ... FEBS letters 584 (8), 1543-1548, 2010 | 239 | 2010 |
Binding of amino acid side-chains to S1 cavities of serine proteinases W Lu, I Apostol, MA Qasim, N Warne, R Wynn, WL Zhang, S Anderson, ... Journal of molecular biology 266 (2), 441-461, 1997 | 215 | 1997 |
Chiral protein supraparticles for tumor suppression and synergistic immunotherapy: an enabling strategy for bioactive supramolecular chirality construction J Yan, Y Yao, S Yan, R Gao, W Lu, W He Nano letters 20 (8), 5844-5852, 2020 | 191 | 2020 |
Dying and necrotic neutrophils are anti-inflammatory secondary to the release of α-defensins K Miles, DJ Clarke, W Lu, Z Sibinska, PE Beaumont, DJ Davidson, ... The Journal of Immunology 183 (3), 2122-2132, 2009 | 191 | 2009 |
Defensins: a double-edged sword in host immunity D Xu, W Lu Frontiers in immunology 11, 764, 2020 | 182 | 2020 |
Induction of group A Streptococcus virulence by a human antimicrobial peptide I Gryllos, HJ Tran-Winkler, MF Cheng, H Chung, R Bolcome III, W Lu, ... Proceedings of the National Academy of Sciences 105 (43), 16755-16760, 2008 | 167 | 2008 |
Insight into the mechanisms of adenovirus capsid disassembly from studies of defensin neutralization JG Smith, M Silvestry, S Lindert, W Lu, GR Nemerow, PL Stewart PLoS pathogens 6 (6), e1000959, 2010 | 162 | 2010 |