| Histone demethylation mediated by the nuclear amine oxidase homolog LSD1 Y Shi, F Lan, C Matson, P Mulligan, JR Whetstine, PA Cole, RA Casero, ... Cell 119 (7), 941-953, 2004 | 5081 | 2004 |
| An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor X Zhang, J Gureasko, K Shen, PA Cole, J Kuriyan Cell 125 (6), 1137-1149, 2006 | 1875 | 2006 |
| Expressed protein ligation: a general method for protein engineering TW Muir, D Sondhi, PA Cole Proceedings of the National Academy of Sciences 95 (12), 6705-6710, 1998 | 1517 | 1998 |
| Acetylation of tau inhibits its degradation and contributes to tauopathy SW Min, SH Cho, Y Zhou, S Schroeder, V Haroutunian, WW Seeley, ... Neuron 67 (6), 953-966, 2010 | 1025 | 2010 |
| Ghrelin TD Müller, R Nogueiras, ML Andermann, ZB Andrews, SD Anker, ... Molecular metabolism 4 (6), 437-460, 2015 | 1021 | 2015 |
| Virtual ligand screening of the p300/CBP histone acetyltransferase: identification of a selective small molecule inhibitor EM Bowers, G Yan, C Mukherjee, A Orry, L Wang, MA Holbert, NT Crump, ... Chemistry & biology 17 (5), 471-482, 2010 | 706 | 2010 |
| A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange Y Liu, R Dentin, D Chen, S Hedrick, K Ravnskjaer, S Schenk, J Milne, ... Nature 456 (7219), 269-273, 2008 | 637 | 2008 |
| Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours LM Lasko, CG Jakob, RP Edalji, W Qiu, D Montgomery, EL Digiammarino, ... Nature 550 (7674), 128-132, 2017 | 598 | 2017 |
| Butyrate greatly enhances derivation of human induced pluripotent stem cells by promoting epigenetic remodeling and the expression of pluripotency-associated genes P Mali, BK Chou, J Yen, Z Ye, J Zou, S Dowey, RA Brodsky, JE Ohm, ... Stem cells 28 (4), 713-720, 2010 | 568 | 2010 |
| Protein lysine acetylation by p300/CBP BM Dancy, PA Cole Chemical reviews 115 (6), 2419-2452, 2015 | 506 | 2015 |
| The structural basis of protein acetylation by the p300/CBP transcriptional coactivator X Liu, L Wang, K Zhao, PR Thompson, Y Hwang, R Marmorstein, PA Cole Nature 451 (7180), 846-850, 2008 | 506 | 2008 |
| Regulation of the p300 HAT domain via a novel activation loop PR Thompson, D Wang, L Wang, M Fulco, N Pediconi, D Zhang, W An, ... Nature structural & molecular biology 11 (4), 308-315, 2004 | 493 | 2004 |
| HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF OD Lau, TK Kundu, RE Soccio, S Ait-Si-Ali, EM Khalil, A Vassilev, ... Molecular cell 5 (3), 589-595, 2000 | 466 | 2000 |
| DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes A Costanzo, P Merlo, N Pediconi, M Fulco, V Sartorelli, PA Cole, ... Molecular cell 9 (1), 175-186, 2002 | 396 | 2002 |
| Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface X Zhang, KA Pickin, R Bose, N Jura, PA Cole, J Kuriyan Nature 450 (7170), 741-744, 2007 | 395 | 2007 |
| Time-resolved analysis reveals rapid dynamics and broad scope of the CBP/p300 acetylome BT Weinert, T Narita, S Satpathy, B Srinivasan, BK Hansen, C Schölz, ... Cell 174 (1), 231-244. e12, 2018 | 367 | 2018 |
| Mechanism and inhibition of cytochrome P-450 aromatase PA Cole, CH Robinson Journal of medicinal chemistry 33 (11), 2933-2942, 1990 | 360 | 1990 |
| A Src-like inactive conformation in the abl tyrosine kinase domain NM Levinson, O Kuchment, K Shen, MA Young, M Koldobskiy, M Karplus, ... PLoS biology 4 (5), e144, 2006 | 355 | 2006 |
| Site-specific incorporation of a phosphotyrosine mimetic reveals a role for tyrosine phosphorylation of SHP-2 in cell signaling W Lu, D Gong, D Bar-Sagi, PA Cole Molecular cell 8 (4), 759-769, 2001 | 340 | 2001 |
| Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor BP Barnett, Y Hwang, MS Taylor, H Kirchner, PT Pfluger, V Bernard, Y Lin, ... Science 330 (6011), 1689-1692, 2010 | 303 | 2010 |
