HPV-16 E5 down-regulates expression of surface HLA class I and reduces recognition by CD8 T cells MS Campo, SV Graham, MS Cortese, GH Ashrafi, EH Araibi, ES Dornan, ... Virology 407 (1), 137-142, 2010 | 213 | 2010 |
The pentameric complex drives immunologically covert cell–cell transmission of wild-type human cytomegalovirus I Murrell, C Bedford, K Ladell, KL Miners, DA Price, P Tomasec, ... Proceedings of the National Academy of Sciences 114 (23), 6104-6109, 2017 | 106 | 2017 |
CD3ζ-based chimeric antigen receptors mediate T cell activation via cis- and trans-signalling mechanisms: implications for optimization of receptor structure for … JS Bridgeman, K Ladell, VE Sheard, K Miners, RE Hawkins, DA Price, ... Clinical & Experimental Immunology 175 (2), 258-267, 2014 | 98 | 2014 |
CCR8 expression defines tissue-resident memory T cells in human skin ML McCully, K Ladell, R Andrews, RE Jones, KL Miners, L Roger, ... The Journal of Immunology 200 (5), 1639-1650, 2018 | 97 | 2018 |
HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells RJ Stanton, V Prod’homme, MA Purbhoo, M Moore, RJ Aicheler, ... Cell host & microbe 16 (2), 201-214, 2014 | 94 | 2014 |
Human stem cell-like memory T cells are maintained in a state of dynamic flux R Ahmed, L Roger, PC Del Amo, KL Miners, RE Jones, L Boelen, T Fali, ... Cell reports 17 (11), 2811-2818, 2016 | 88 | 2016 |
Human TSCM cell dynamics in vivo are compatible with long-lived immunological memory and stemness P Costa Del Amo, J Lahoz-Beneytez, L Boelen, R Ahmed, KL Miners, ... PLoS biology 16 (6), e2005523, 2018 | 72 | 2018 |
TRAV1-2+ CD8+ T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis EB Wong, MC Gold, EW Meermeier, BZ Xulu, S Khuzwayo, ZA Sullivan, ... Communications biology 2 (1), 203, 2019 | 66 | 2019 |
T cell autoreactivity directed toward CD1c itself rather than toward carried self lipids KS Wun, JF Reijneveld, TY Cheng, K Ladell, AP Uldrich, J Le Nours, ... Nature immunology 19 (4), 397-406, 2018 | 60 | 2018 |
Inhibitory killer cell immunoglobulin-like receptors strengthen CD8+ T cell–mediated control of HIV-1, HCV, and HTLV-1 L Boelen, B Debebe, M Silveira, A Salam, J Makinde, CH Roberts, ... Science immunology 3 (29), eaao2892, 2018 | 57 | 2018 |
Naive CD8+ T‐cell precursors display structured TCR repertoires and composite antigen‐driven selection dynamics MA Neller, K Ladell, JE McLaren, KK Matthews, E Gostick, JM Pentier, ... Immunology and cell biology 93 (7), 625-633, 2015 | 51 | 2015 |
Young women with polycystic ovary syndrome have raised levels of circulating annexin V-positive platelet microparticles GR Willis, K Connolly, K Ladell, TS Davies, IA Guschina, D Ramji, ... Human Reproduction 29 (12), 2756-2763, 2014 | 42 | 2014 |
A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans SC Edwards, CE Sutton, K Ladell, EJ Grant, JE McLaren, F Roche, ... Journal of Experimental Medicine 217 (5), e20190834, 2020 | 41 | 2020 |
Germline bias dictates cross-serotype reactivity in a common dengue-virus-specific CD8+ T cell response A Culshaw, K Ladell, S Gras, JE McLaren, KL Miners, C Farenc, ... Nature immunology 18 (11), 1228-1237, 2017 | 39 | 2017 |
Clonality of HTLV-2 in natural infection A Melamed, AD Witkover, DJ Laydon, R Brown, K Ladell, K Miners, ... PLoS Pathogens 10 (3), e1004006, 2014 | 39 | 2014 |
Epitope specificity and longevity of a vaccine-induced human T cell response against HPV18 KL Smith, A Tristram, KM Gallagher, AN Fiander, S Man International immunology 17 (2), 167-176, 2005 | 39 | 2005 |
Cellular-level versus receptor-level response threshold hierarchies in T-cell activation HA van den Berg, K Ladell, K Miners, B Laugel, S Llewellyn-Lacey, ... Frontiers in immunology 4, 250, 2013 | 34 | 2013 |
Cross‐typic specificity and immunotherapeutic potential of a human HPV16 E7‐specific CTL line SJ Youde, CM McCarthy, KJ Thomas, KL Smith, S Man International Journal of Cancer 114 (4), 606-612, 2005 | 34 | 2005 |
Human CLEC9A antibodies deliver Wilms' tumor 1 (WT1) antigen to CD141+ dendritic cells to activate naïve and memory WT1‐specific CD8+ T cells FE Pearson, KM Tullett, IM Leal‐Rojas, OL Haigh, KA Masterman, ... Clinical & translational immunology 9 (6), e1141, 2020 | 33 | 2020 |
Monoclonal antibodies targeting nonstructural viral antigens can activate ADCC against human cytomegalovirus VM Vlahava, I Murrell, L Zhuang, RJ Aicheler, E Lim, KL Miners, K Ladell, ... The Journal of clinical investigation 131 (4), 2021 | 30 | 2021 |