Genome-wide profiling in colorectal cancer identifies PHF19 and TBC1D16 as oncogenic super enhancers QL Li, X Lin, YL Yu, L Chen, QX Hu, M Chen, N Cao, C Zhao, CY Wang, ... Nature communications 12 (1), 6407, 2021 | 69 | 2021 |
Histone demethylase KDM3A is required for enhancer activation of hippo target genes in colorectal cancer HY Wang, QY Long, SB Tang, Q Xiao, C Gao, QY Zhao, QL Li, M Ye, ... Nucleic Acids Research 47 (5), 2349-2364, 2019 | 63 | 2019 |
The hyper-activation of transcriptional enhancers in breast cancer QL Li, DY Wang, LG Ju, J Yao, C Gao, PJ Lei, LY Li, XL Zhao, M Wu Clinical epigenetics 11, 1-17, 2019 | 60 | 2019 |
FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis ZS Xu, HX Zhang, WW Li, Y Ran, TT Liu, MG Xiong, QL Li, SY Wang, ... Proceedings of the National Academy of Sciences 116 (21), 10447-10452, 2019 | 60 | 2019 |
Mutant NPM1 hijacks transcriptional hubs to maintain pathogenic gene programs in acute myeloid leukemia XQD Wang, D Fan, Q Han, Y Liu, H Miao, X Wang, Q Li, D Chen, H Gore, ... Cancer discovery 13 (3), 724-745, 2023 | 46 | 2023 |
Small-molecule inhibition of the acyl-lysine reader ENL as a strategy against acute myeloid leukemia Y Liu, Q Li, F Alikarami, DR Barrett, L Mahdavi, H Li, S Tang, TA Khan, ... Cancer discovery 12 (11), 2684-2709, 2022 | 45 | 2022 |
Deficiency of histone methyltransferase SET domain‐containing 2 in liver leads to abnormal lipid metabolism and HCC XJ Li, QL Li, LG Ju, C Zhao, LS Zhao, JW Du, Y Wang, L Zheng, BL Song, ... Hepatology 73 (5), 1797-1815, 2021 | 44 | 2021 |
Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer L Song, X Yao, H Li, B Peng, AP Boka, Y Liu, G Chen, Z Liu, KM Mathias, ... Molecular cell 82 (21), 4080-4098. e12, 2022 | 41 | 2022 |
Abnormal neocortex arealization and Sotos-like syndrome–associated behavior in Setd2 mutant mice L Xu, Y Zheng, X Li, A Wang, D Huo, Q Li, S Wang, Z Luo, Y Liu, F Xu, ... Science advances 7 (1), eaba1180, 2021 | 31 | 2021 |
GLIS2 promotes colorectal cancer through repressing enhancer activation J Yao, PJ Lei, QL Li, J Chen, SB Tang, Q Xiao, X Lin, X Wang, LY Li, ... Oncogenesis 9 (5), 57, 2020 | 24 | 2020 |
TTLL12 inhibits the activation of cellular antiviral signaling through interaction with VISA/MAVS LG Ju, Y Zhu, PJ Lei, D Yan, K Zhu, X Wang, QL Li, XJ Li, JW Chen, LY Li, ... The Journal of Immunology 198 (3), 1274-1284, 2017 | 24 | 2017 |
Epigenomic analysis in a cell-based model reveals the roles of H3K9me3 in breast cancer transformation QL Li, PJ Lei, QY Zhao, L Li, G Wei, M Wu Epigenomics 9 (8), 1077-1092, 2017 | 16 | 2017 |
Profiling of histone 3 lysine 27 acetylation reveals its role in a chronic DSS-induced colitis mouse model M Chen, Q Li, N Cao, Y Deng, L Li, Q Zhao, M Wu, M Ye Molecular Omics 15 (4), 296-307, 2019 | 10 | 2019 |
Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma IK Kim, MS Diamond, S Yuan, SB Kemp, BM Kahn, Q Li, JH Lin, J Li, ... Nature Communications 15 (1), 1532, 2024 | 9 | 2024 |
DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance N Zhou, J Choi, G Grothusen, BJ Kim, D Ren, Z Cao, Y Liu, Q Li, ... Blood 142 (11), 973-988, 2023 | 9 | 2023 |
Dynamic Chromatin States Coupling with Key Transcription Factors in Colitis‐Associated Colorectal Cancer L Chen, Z Luo, C Zhao, Q Li, Y Geng, Y Xiao, MK Chen, L Li, ZX Chen, ... Advanced Science 9 (23), 2200536, 2022 | 8 | 2022 |
Epigenetic dysregulation induces translocation of histone H3 into cytoplasm Z Wang, J Chen, C Gao, Q Xiao, XW Wang, SB Tang, QL Li, B Zhong, ... Advanced Science 8 (19), 2100779, 2021 | 8 | 2021 |
Genome-wide enhancer analysis reveals the role of AP-1 transcription factor in head and neck squamous cell carcinoma CY Wang, GT Yu, C Gao, J Chen, QL Li, L Zhang, M Wu, ZJ Sun, LY Li Frontiers in Molecular Biosciences 8, 701531, 2021 | 7 | 2021 |
Characterization of WDR20: A new regulator of the ERAD machinery LG Ju, X Lin, D Yan, QL Li, M Wu, LY Li Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (7), 970-980, 2018 | 5 | 2018 |
Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity T Katsuda, JH Sussman, K Ito, A Katznelson, S Yuan, N Takenaka, J Li, ... Nature Communications 15 (1), 1761, 2024 | 4 | 2024 |