Intermittent access to 20% ethanol induces high ethanol consumption in Long–Evans and Wistar rats JA Simms, P Steensland, B Medina, KE Abernathy, LJ Chandler, R Wise, ... Alcoholism: Clinical and Experimental Research 32 (10), 1816-1823, 2008 | 597 | 2008 |
Chronic ethanol exposure potentiates NMDA excitotoxicity in cerebral cortical neurons LJ Chandler, H Newsom, C Sumners, F Crews Journal of neurochemistry 60 (4), 1578-1581, 1993 | 238 | 1993 |
Alcohol and the prefrontal cortex K Abernathy, LJ Chandler, JJ Woodward International review of neurobiology 91, 289-320, 2010 | 236 | 2010 |
Chronic alcohol exposure alters behavioral and synaptic plasticity of the rodent prefrontal cortex S Kroener, PJ Mulholland, NN New, JT Gass, HC Becker, LJ Chandler PloS one 7 (5), e37541, 2012 | 229 | 2012 |
Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism HT Zhang, AM Crissman, NR Dorairaj, LJ Chandler, JM O'Donnell Neuropsychopharmacology 23 (2), 198-204, 2000 | 199 | 2000 |
Adolescent alcohol exposure reduces behavioral flexibility, promotes disinhibition, and increases resistance to extinction of ethanol self-administration in adulthood JT Gass, WB Glen, JT McGonigal, H Trantham-Davidson, MF Lopez, ... Neuropsychopharmacology 39 (11), 2570-2583, 2014 | 189 | 2014 |
Chronic ethanol induces synaptic but not extrasynaptic targeting of NMDA receptors EP Carpenter-Hyland, JJ Woodward, LJ Chandler Journal of Neuroscience 24 (36), 7859-7868, 2004 | 188 | 2004 |
N-methyl D-aspartate receptor-mediated bidirectional control of extracellular signal-regulated kinase activity in cortical neuronal cultures LJ Chandler, G Sutton, NR Dorairaj, D Norwood Journal of Biological Chemistry 276 (4), 2627-2636, 2001 | 188 | 2001 |
Inhibition of fast-and slow-phase depolarization-dependent synaptosomal calcium uptake by ethanol. SW Leslie, E Barr, J Chandler, RP Farrar Journal of Pharmacology and Experimental Therapeutics 225 (3), 571-575, 1983 | 181 | 1983 |
Ethanol tolerance and synaptic plasticity LJ Chandler, RA Harris, FT Crews Trends in Pharmacological Sciences 19 (12), 491-495, 1998 | 174 | 1998 |
Dopamine modulates persistent synaptic activity and enhances the signal-to-noise ratio in the prefrontal cortex S Kroener, LJ Chandler, PEM Phillips, JK Seamans PloS one 4 (8), e6507, 2009 | 165 | 2009 |
Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus HT Zhang, Y Zhao, Y Huang, NR Dorairaj, LJ Chandler, JM O'Donnell Neuropsychopharmacology 29 (8), 1432-1439, 2004 | 159 | 2004 |
Chronic Ethanol IncreasesN-Methyl-D-Aspartate-Stimulated Nitric Oxide Formation but Not Receptor Density in Cultured Cortical Neurons LJ Chandler, G Sutton, D Norwood, C Sumners, FT Crews Molecular Pharmacology 51 (5), 733-740, 1997 | 156 | 1997 |
The plasticity of extinction: contribution of the prefrontal cortex in treating addiction through inhibitory learning JT Gass, LJ Chandler Frontiers in psychiatry 4, 46, 2013 | 147 | 2013 |
Reduced calcium uptake by rat brain mitochondria and synaptosomes in response to aging SW Leslie, LJ Chandler, EM Barr, RP Farrar Brain research 329 (1-2), 177-183, 1985 | 141 | 1985 |
Chronic ethanol upregulates NMDA and AMPA, but not kainate receptor subunit proteins in rat primary cortical cultures LJ Chandler, D Norwood, G Sutton Alcoholism: Clinical and Experimental Research 23 (2), 363-370, 1999 | 140 | 1999 |
Successful choice behavior is associated with distinct and coherent network states in anterior cingulate cortex CC Lapish, D Durstewitz, LJ Chandler, JK Seamans Proceedings of the National Academy of Sciences 105 (33), 11963-11968, 2008 | 139 | 2008 |
Ethanol inhibits NMDA receptor‐mediated excitotoxicity in rat primary neuronal cultures LJ Chandler, C Sumners, FT Crews Alcoholism: Clinical and Experimental Research 17 (1), 54-60, 1993 | 139 | 1993 |
Ethanol inhibits persistent activity in prefrontal cortical neurons Y Tu, S Kroener, K Abernathy, C Lapish, J Seamans, LJ Chandler, ... Journal of Neuroscience 27 (17), 4765-4775, 2007 | 138 | 2007 |
Adaptive plasticity of NMDA receptors and dendritic spines: implications for enhanced vulnerability of the adolescent brain to alcohol addiction EP Carpenter-Hyland, LJ Chandler Pharmacology Biochemistry and Behavior 86 (2), 200-208, 2007 | 138 | 2007 |