Structure of the 30S translation initiation complex A Simonetti, S Marzi, AG Myasnikov, A Fabbretti, M Yusupov, CO Gualerzi, ... Nature 455 (7211), 416-420, 2008 | 264 | 2008 |
Escherichia coli Ribosomal Protein S1 Unfolds Structured mRNAs Onto the Ribosome for Active Translation Initiation M Duval, A Korepanov, O Fuchsbauer, P Fechter, A Haller, A Fabbretti, ... PLoS biology 11 (12), e1001731, 2013 | 193 | 2013 |
Transient kinetics, fluorescence, and FRET in studies of initiation of translation in bacteria P Milon, AL Konevega, F Peske, A Fabbretti, CO Gualerzi, MV Rodnina Methods in enzymology 430, 1-30, 2007 | 137 | 2007 |
Antibiotics: targets, mechanisms and resistance CO Gualerzi, L Brandi, A Fabbretti, CL Pon John Wiley & Sons, 2013 | 135 | 2013 |
Specific, efficient, and selective inhibition of prokaryotic translation initiation by a novel peptide antibiotic L Brandi, A Fabbretti, A La Teana, M Abbondi, D Losi, S Donadio, ... Proceedings of the National Academy of Sciences 103 (1), 39-44, 2006 | 85 | 2006 |
How to cope with the quest for new antibiotics A Fabbretti, CO Gualerzi, L Brandi FEBS letters 585 (11), 1673-1681, 2011 | 84 | 2011 |
The real-time path of translation factor IF3 onto and off the ribosome A Fabbretti, CL Pon, SP Hennelly, WE Hill, JS Lodmell, CO Gualerzi Molecular cell 25 (2), 285-296, 2007 | 81 | 2007 |
Novel tetrapeptide inhibitors of bacterial protein synthesis produced by a Streptomyces sp. L Brandi, A Lazzarini, L Cavaletti, M Abbondi, E Corti, I Ciciliato, ... Biochemistry 45 (11), 3692-3702, 2006 | 68 | 2006 |
Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor A Simonetti, S Marzi, IML Billas, A Tsai, A Fabbretti, AG Myasnikov, ... Proceedings of the National Academy of Sciences 110 (39), 15656-15661, 2013 | 65 | 2013 |
Engineering color variants of green fluorescent protein (GFP) for thermostability, pH-sensitivity, and improved folding kinetics N Aliye, A Fabbretti, G Lupidi, T Tsekoa, R Spurio Applied microbiology and biotechnology 99, 1205-1216, 2015 | 61 | 2015 |
The translation initiation functions of IF2: targets for thiostrepton inhibition L Brandi, S Marzi, A Fabbretti, C Fleischer, WE Hill, CO Gualerzi, ... Journal of molecular biology 335 (4), 881-894, 2004 | 58 | 2004 |
Methods for identifying compounds that specifically target translation L Brandi, A Fabbretti, P Milon, M Carotti, CL Pon, CO Gualerzi Methods in enzymology 431, 229-267, 2007 | 45 | 2007 |
Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding A Fabbretti, A Schedlbauer, L Brandi, T Kaminishi, AM Giuliodori, ... Proceedings of the National Academy of Sciences 113 (16), E2286-E2295, 2016 | 44 | 2016 |
The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation D Bulkley, L Brandi, YS Polikanov, A Fabbretti, M O’Connor, CO Gualerzi, ... Cell reports 6 (2), 357-365, 2014 | 43 | 2014 |
Structure of the protein core of translation initiation factor 2 in apo, GTP-bound and GDP-bound forms A Simonetti, S Marzi, A Fabbretti, I Hazemann, L Jenner, A Urzhumtsev, ... Acta Crystallographica Section D: Biological Crystallography 69 (6), 925-933, 2013 | 41 | 2013 |
Translation initiation complex formation in the crenarchaeon Sulfolobus solfataricus D Hasenöhrl, A Fabbretti, P Londei, CO Gualerzi, U Bläsi Rna 15 (12), 2288-2298, 2009 | 41 | 2009 |
Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways JP Lopez-Alonso, A Fabbretti, T Kaminishi, I Iturrioz, L Brandi, ... Nucleic acids research 45 (4), 2179-2187, 2017 | 39 | 2017 |
The antibiotic Furvina® targets the P-site of 30S ribosomal subunits and inhibits translation initiation displaying start codon bias A Fabbretti, L Brandi, D Petrelli, CL Pon, NR Castanedo, R Medina, ... Nucleic acids research 40 (20), 10366-10374, 2012 | 39 | 2012 |
Characterization of GE82832, a peptide inhibitor of translocation interacting with bacterial 30S ribosomal subunits L Brandi, A Fabbretti, M Di Stefano, A Lazzarini, M Abbondi, CO Gualerzi Rna 12 (7), 1262-1270, 2006 | 33 | 2006 |
Role of temperature-independent lipoplex-cell membrane interactions in the efficiency boost of multicomponent lipoplexes. CG Marchini C, Pozzi D, Montani M, Alfonsi C, Amici A, Candeloro De Sanctis ... Cancer Gene Ther., 2011 | 30 | 2011 |