β-Catenin regulates expression of cyclin D1 in colon carcinoma cells O Tetsu, F McCormick Nature 398 (6726), 422-426, 1999 | 4595 | 1999 |
The GTPase superfamily: conserved structure and molecular mechanism HR Bourne, DA Sanders, F McCormick nature 349 (6305), 117-127, 1991 | 4494 | 1991 |
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes RM Neve, K Chin, J Fridlyand, J Yeh, FL Baehner, T Fevr, L Clark, ... Cancer cell 10 (6), 515-527, 2006 | 3770 | 2006 |
The GTPase superfamily: a conserved switch for diverse cell functions HR Bourne, DA Sanders, F McCormick Nature 348 (6297), 125-132, 1990 | 3135 | 1990 |
Proteins regulating Ras and its relatives MS Boguski, F McCormick Nature 366 (6456), 643-654, 1993 | 2668 | 1993 |
Oncogenic signaling pathways in the cancer genome atlas F Sanchez-Vega, M Mina, J Armenia, WK Chatila, A Luna, KC La, ... Cell 173 (2), 321-337. e10, 2018 | 2505 | 2018 |
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells JR Bischoff, DH Kirn, A Williams, C Heise, S Horn, M Muna, L Ng, JA Nye, ... Science 274 (5286), 373-376, 1996 | 2393 | 1996 |
The RB and p53 pathways in cancer CJ Sherr, F McCormick Cancer cell 2 (2), 103-112, 2002 | 2282 | 2002 |
RAS proteins and their regulators in human disease DK Simanshu, DV Nissley, F McCormick Cell 170 (1), 17-33, 2017 | 1655 | 2017 |
Dual role of phosphatidylinositol-3, 4, 5-trisphosphate in the activation of protein kinase B D Stokoe, LR Stephens, T Copeland, PRJ Gaffney, CB Reese, GF Painter, ... Science 277 (5325), 567-570, 1997 | 1642 | 1997 |
A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants M Trahey, F McCormick Science 238 (4826), 542-545, 1987 | 1587 | 1987 |
Protein kinase B kinases that mediate phosphatidylinositol 3, 4, 5-trisphosphate-dependent activation of protein kinase B L Stephens, K Anderson, D Stokoe, H Erdjument-Bromage, GF Painter, ... Science 279 (5351), 710-714, 1998 | 1434 | 1998 |
Two G protein oncogenes in human endocrine tumors J Lyons, CA Landis, G Harsh, L Vallar, K Grünewald, H Feichtinger, ... Science 249 (4969), 655-659, 1990 | 1259 | 1990 |
ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents C Heise, A Sampson-Johannes, A Williams, F Mccormick, DD Von Hoff, ... Nature medicine 3 (6), 639-645, 1997 | 1237 | 1997 |
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition MJ Hangauer, VS Viswanathan, MJ Ryan, D Bole, JK Eaton, A Matov, ... Nature 551 (7679), 247-250, 2017 | 1230 | 2017 |
Inhibition by cAMP of Ras-dependent activation of Raf SJ Cook, F McCormick Science 262 (5136), 1069-1072, 1993 | 1193 | 1993 |
The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21 GA Martin, D Viskoohil, G Bollag, PC McCabe, WJ Crosier, H Haubruck, ... Cell 63 (4), 843-849, 1990 | 1174 | 1990 |
Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation LA Timmerman, J Grego-Bessa, A Raya, E Bertrán, JM Pérez-Pomares, ... Genes & development 18 (1), 99-115, 2004 | 1150 | 2004 |
An essential role for Rac in Ras transformation RG Qiu, J Chen, D Kirn, F McCormick, M Symons Nature 374 (6521), 457-459, 1995 | 1149 | 1995 |
Wiskott–Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization M Symons, JMJ Derry, B Karlak, S Jiang, V Lemahieu, F McCormick, ... Cell 84 (5), 723-734, 1996 | 1070 | 1996 |