Analysis of Oct4-dependent transcriptional networks regulating self-renewal and pluripotency in human embryonic stem cells Y Babaie, R Herwig, B Greber, TC Brink, W Wruck, D Groth, H Lehrach, ... Stem cells 25 (2), 500-510, 2007 | 488 | 2007 |
The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle HJ Warnatz, D Schmidt, T Manke, I Piccini, M Sultan, T Borodina, ... Journal of Biological Chemistry 286 (26), 23521-23532, 2011 | 197 | 2011 |
Induced pluripotent stem cell-derived neuronal cells from a sporadic Alzheimer’s disease donor as a model for investigating AD-associated gene regulatory networks AM Hossini, M Megges, A Prigione, B Lichtner, MR Toliat, W Wruck, ... BMC genomics 16, 1-22, 2015 | 154 | 2015 |
Automated image analysis for array hybridization experiments M Steinfath, W Wruck, H Seidel, H Lehrach, U Radelof, J O’Brien Bioinformatics 17 (7), 634-641, 2001 | 146 | 2001 |
Substrate-dependent regulation of anaerobic degradation pathways for toluene and ethylbenzene in a denitrifying bacterium, strain EbN1 S Kühner, L Wöhlbrand, I Fritz, W Wruck, C Hultschig, P Hufnagel, ... Journal of bacteriology 187 (4), 1493-1503, 2005 | 142 | 2005 |
The nerve growth factor receptor CD271 is crucial to maintain tumorigenicity and stem-like properties of melanoma cells T Redmer, Y Welte, D Behrens, I Fichtner, D Przybilla, W Wruck, ... PloS one 9 (5), e92596, 2014 | 108 | 2014 |
Modeling nonalcoholic fatty liver disease with human pluripotent stem cell-derived immature hepatocyte-like cells reveals activation of PLIN2 and confirms regulatory functions … N Graffmann, S Ring, MA Kawala, W Wruck, A Ncube, HI Trompeter, ... Stem cells and development 25 (15), 1119-1133, 2016 | 104 | 2016 |
Cross-species hybridisation of human and bovine orthologous genes on high density cDNA microarrays J Adjaye, R Herwig, D Herrmann, W Wruck, A BenKahla, TC Brink, ... BMC genomics 5, 1-12, 2004 | 104 | 2004 |
Human iPSC-derived MSCs (iMSCs) from aged individuals acquire a rejuvenation signature LS Spitzhorn, M Megges, W Wruck, MS Rahman, J Otte, Ö Degistirici, ... Stem cell research & therapy 10, 1-18, 2019 | 101 | 2019 |
Isolation and molecular characterization of amniotic fluid‐derived mesenchymal stem cells obtained from caesarean sections LS Spitzhorn, MS Rahman, L Schwindt, HT Ho, W Wruck, M Bohndorf, ... Stem cells international 2017 (1), 5932706, 2017 | 69 | 2017 |
Construction of a ‘unigene’cDNA clone set by oligonucleotide fingerprinting allows access to 25 000 potential sugar beet genes R Herwig, B Schulz, B Weisshaar, S Hennig, M Steinfath, M Drungowski, ... The Plant Journal 32 (5), 845-857, 2002 | 67 | 2002 |
Concise review: current status and future directions on research related to nonalcoholic fatty liver disease W Wruck, N Graffmann, MA Kawala, J Adjaye Stem Cells 35 (1), 89-96, 2017 | 52 | 2017 |
Multi-omic profiles of human non-alcoholic fatty liver disease tissue highlight heterogenic phenotypes W Wruck, K Kashofer, S Rehman, A Daskalaki, D Berg, E Gralka, ... Scientific data 2 (1), 1-10, 2015 | 47 | 2015 |
Data management strategies for multinational large-scale systems biology projects W Wruck, M Peuker, CRA Regenbrecht Briefings in bioinformatics 15 (1), 65-78, 2014 | 45 | 2014 |
Meta-analysis of human prefrontal cortex reveals activation of GFAP and decline of synaptic transmission in the aging brain W Wruck, J Adjaye Acta Neuropathologica Communications 8, 1-18, 2020 | 41 | 2020 |
Human iPSC-derived iMSCs improve bone regeneration in mini-pigs P Jungbluth, LS Spitzhorn, J Grassmann, S Tanner, D Latz, MS Rahman, ... Bone research 7 (1), 32, 2019 | 39 | 2019 |
SARS-CoV-2 receptor ACE2 is co-expressed with genes related to transmembrane serine proteases, viral entry, immunity and cellular stress W Wruck, J Adjaye Scientific Reports 10 (1), 21415, 2020 | 38 | 2020 |
FGF signalling in the self-renewal of colon cancer organoids J Otte, L Dizdar, B Behrens, W Goering, WT Knoefel, W Wruck, ... Scientific Reports 9 (1), 17365, 2019 | 38 | 2019 |
The FGF, TGFβ and WNT axis Modulate Self-renewal of Human SIX2+ Urine Derived Renal Progenitor Cells MS Rahman, W Wruck, LS Spitzhorn, L Nguyen, M Bohndorf, S Martins, ... Scientific reports 10 (1), 739, 2020 | 37 | 2020 |
Pluripotent stem cells: induction and self-renewal R Abu-Dawud, N Graffmann, S Ferber, W Wruck, J Adjaye Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 33 | 2018 |