A stem cell molecular signature NB Ivanova, JT Dimos, C Schaniel, JA Hackney, KA Moore, IR Lemischka Science 298 (5593), 601-604, 2002 | 1848 | 2002 |
The immunoreceptor TIGIT regulates antitumor and antiviral CD8+ T cell effector function RJ Johnston, L Comps-Agrar, J Hackney, X Yu, M Huseni, Y Yang, S Park, ... Cancer cell 26 (6), 923-937, 2014 | 1141 | 2014 |
Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations R Bueno, EW Stawiski, LD Goldstein, S Durinck, A De Rienzo, ... Nature genetics 48 (4), 407-416, 2016 | 840 | 2016 |
IL-17C regulates the innate immune function of epithelial cells in an autocrine manner V Ramirez-Carrozzi, A Sambandam, E Luis, Z Lin, S Jeet, J Lesch, ... Nature immunology 12 (12), 1159-1166, 2011 | 510 | 2011 |
Synovial phenotypes in rheumatoid arthritis correlate with response to biologic therapeutics G Dennis, CTJ Holweg, SK Kummerfeld, DF Choy, AF Setiadi, ... Arthritis research & therapy 16, 1-18, 2014 | 374 | 2014 |
A genomic regulatory element that directs assembly and function of immune-specific AP-1–IRF complexes E Glasmacher, S Agrawal, AB Chang, TL Murphy, W Zeng, B Vander Lugt, ... Science 338 (6109), 975-980, 2012 | 373 | 2012 |
Molecular portraits of early rheumatoid arthritis identify clinical and treatment response phenotypes MJ Lewis, MR Barnes, K Blighe, K Goldmann, S Rana, JA Hackney, ... Cell reports 28 (9), 2455-2470. e5, 2019 | 296 | 2019 |
A molecular profile of a hematopoietic stem cell niche JA Hackney, P Charbord, BP Brunk, CJ Stoeckert, IR Lemischka, ... Proceedings of the National Academy of Sciences 99 (20), 13061-13066, 2002 | 293 | 2002 |
Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation B Vander Lugt, AA Khan, JA Hackney, S Agrawal, J Lesch, M Zhou, ... Nature immunology 15 (2), 161-167, 2014 | 289 | 2014 |
Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients F Humby, M Lewis, N Ramamoorthi, JA Hackney, MR Barnes, ... Annals of the rheumatic diseases 78 (6), 761-772, 2019 | 271 | 2019 |
Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells S Rutz, R Noubade, C Eidenschenk, N Ota, W Zeng, Y Zheng, J Hackney, ... Nature immunology 12 (12), 1238-1245, 2011 | 234 | 2011 |
NRROS negatively regulates reactive oxygen species during host defence and autoimmunity R Noubade, K Wong, N Ota, S Rutz, C Eidenschenk, PA Valdez, J Ding, ... Nature 509 (7499), 235-239, 2014 | 230 | 2014 |
Integration of eQTL and a single-cell atlas in the human eye identifies causal genes for age-related macular degeneration LD Orozco, HH Chen, C Cox, KJ Katschke, R Arceo, C Espiritu, P Caplazi, ... Cell reports 30 (4), 1246-1259. e6, 2020 | 166 | 2020 |
Association between response to etrolizumab and expression of integrin αE and granzyme A in colon biopsies of patients with ulcerative colitis GW Tew, JA Hackney, D Gibbons, CA Lamb, D Luca, JG Egen, L Diehl, ... Gastroenterology 150 (2), 477-487. e9, 2016 | 166 | 2016 |
c-Maf-dependent Treg cell control of intestinal TH17 cells and IgA establishes host–microbiota homeostasis C Neumann, J Blume, U Roy, PP Teh, A Vasanthakumar, A Beller, Y Liao, ... Nature immunology 20 (4), 471-481, 2019 | 160 | 2019 |
Identification of developmentally regulated genes in Entamoeba histolytica: insights into mechanisms of stage conversion in a protozoan parasite GM Ehrenkaufer, R Haque, JA Hackney, DJ Eichinger, U Singh Cellular microbiology 9 (6), 1426-1444, 2007 | 155 | 2007 |
Functional studies on the IBD susceptibility gene IL23R implicate reduced receptor function in the protective genetic variant R381Q S Pidasheva, S Trifari, A Phillips, JA Hackney, Y Ma, A Smith, SJ Sohn, ... PloS one 6 (10), e25038, 2011 | 139 | 2011 |
NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus HD Brightbill, E Suto, N Blaquiere, N Ramamoorthi, S Sujatha-Bhaskar, ... Nature communications 9 (1), 179, 2018 | 115 | 2018 |
Selective autophagy of the adaptor TRIF regulates innate inflammatory signaling M Samie, J Lim, E Verschueren, JM Baughman, I Peng, A Wong, Y Kwon, ... Nature immunology 19 (3), 246-254, 2018 | 108 | 2018 |
Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent … G Lliso-Ribera, F Humby, M Lewis, A Nerviani, D Mauro, F Rivellese, ... Annals of the rheumatic diseases 78 (12), 1642-1652, 2019 | 97 | 2019 |