| Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal KS Yan, CY Janda, J Chang, GXY Zheng, KA Larkin, VC Luca, LA Chia, ... Nature 545 (7653), 238-242, 2017 | 432 | 2017 |
| Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer JS Lim, A Ibaseta, MM Fischer, B Cancilla, G O’Young, S Cristea, VC Luca, ... Nature 545 (7654), 360-364, 2017 | 417 | 2017 |
| Progenitor identification and SARS-CoV-2 infection in human distal lung organoids AA Salahudeen, SS Choi, A Rustagi, J Zhu, V van Unen, SM de la O, ... Nature 588 (7839), 670-675, 2020 | 356 | 2020 |
| Structural basis for Notch1 engagement of Delta-like 4 VC Luca, KM Jude, NW Pierce, MV Nachury, S Fischer, KC Garcia Science 347 (6224), 847-853, 2015 | 302 | 2015 |
| Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity VC Luca, BC Kim, C Ge, S Kakuda, D Wu, M Roein-Peikar, ... Science 355 (6331), 1320-1324, 2017 | 299 | 2017 |
| Antibodies to interleukin-2 elicit selective T cell subset potentiation through distinct conformational mechanisms JB Spangler, J Tomala, VC Luca, KM Jude, S Dong, AM Ring, P Votavova, ... Immunity 42 (5), 815-825, 2015 | 246 | 2015 |
| Crystal structure of the Japanese encephalitis virus envelope protein VC Luca, J AbiMansour, CA Nelson, DH Fremont Journal of virology 86 (4), 2337-2346, 2012 | 234 | 2012 |
| The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake Á de Mingo Pulido, K Hänggi, DP Celias, A Gardner, J Li, ... Immunity 54 (6), 1154-1167. e7, 2021 | 145 | 2021 |
| Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step MC Sabo, VC Luca, J Prentoe, SE Hopcraft, KJ Blight, MK Yi, SM Lemon, ... Journal of virology 85 (14), 7005-7019, 2011 | 145 | 2011 |
| Structural basis of GPBAR activation and bile acid recognition F Yang, C Mao, L Guo, J Lin, Q Ming, P Xiao, X Wu, Q Shen, S Guo, ... Nature 587 (7834), 499-504, 2020 | 119 | 2020 |
| BTN3A1 governs antitumor responses by coordinating αβ and γδ T cells KK Payne, JA Mine, S Biswas, RA Chaurio, A Perales-Puchalt, ... Science 369 (6506), 942-949, 2020 | 110 | 2020 |
| Inhibition of Delta-induced Notch signaling using fucose analogs M Schneider, V Kumar, LU Nordstrøm, L Feng, H Takeuchi, H Hao, ... Nature chemical biology 14 (1), 65-71, 2018 | 57 | 2018 |
| LAG3 ectodomain structure reveals functional interfaces for ligand and antibody recognition Q Ming, DP Celias, C Wu, AR Cole, S Singh, C Mason, S Dong, TH Tran, ... Nature immunology 23 (7), 1031-1041, 2022 | 41 | 2022 |
| Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature MC Sabo, VC Luca, SC Ray, J Bukh, DH Fremont, MS Diamond Virology 422 (2), 174-184, 2012 | 38 | 2012 |
| Fucosylation of HLA-DRB1 regulates CD4+ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy DK Lester, C Burton, A Gardner, P Innamarato, K Kodumudi, Q Liu, ... Nature cancer 4 (2), 222-239, 2023 | 28 | 2023 |
| Structure of the St. Louis encephalitis virus postfusion envelope trimer VC Luca, CA Nelson, DH Fremont Journal of virology 87 (2), 818-828, 2013 | 27 | 2013 |
| Surrogate R-spondins for tissue-specific potentiation of Wnt Signaling VC Luca, Y Miao, X Li, MJ Hollander, CJ Kuo, KC Garcia PloS one 15 (1), e0226928, 2020 | 21 | 2020 |
| A library of infectious hepatitis C viruses with engineered mutations in the E2 gene reveals growth-adaptive mutations that modulate interactions with scavenger receptor class … A Zuiani, K Chen, MC Schwarz, JP White, VC Luca, DH Fremont, D Wang, ... Journal of virology 90 (23), 10499-10512, 2016 | 18 | 2016 |
| Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling D Gonzalez-Perez, S Das, D Antfolk, HS Ahsan, E Medina, CE Dundes, ... Nature chemical biology 19 (1), 9-17, 2023 | 17 | 2023 |
| Functional comparison between endogenous and synthetic notch systems B Khamaisi, VC Luca, SC Blacklow, D Sprinzak ACS Synthetic Biology 11 (10), 3343-3353, 2022 | 13 | 2022 |
