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Designing and executing prime editing experiments in mammalian cells JL Doman, AA Sousa, PB Randolph, PJ Chen, DR Liu Nature protocols 17 (11), 2431-2468, 2022 | 59 | 2022 |
Ex vivo prime editing of patient haematopoietic stem cells rescues sickle-cell disease phenotypes after engraftment in mice KA Everette, GA Newby, RM Levine, K Mayberry, Y Jang, T Mayuranathan, ... Nature biomedical engineering 7 (5), 616-628, 2023 | 51 | 2023 |
Adenine transversion editors enable precise, efficient A• T-to-C• G base editing in mammalian cells and embryos L Chen, M Hong, C Luan, H Gao, G Ru, X Guo, D Zhang, S Zhang, C Li, ... Nature biotechnology 42 (4), 638-650, 2024 | 49 | 2024 |
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Publisher Correction: Engineered CRISPR-Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ... Nature biotechnology 38 (7), 901, 2020 | 4 | 2020 |
Variants of cpf1 (cas12a) with altered pam specificity JK Joung, B KLEINSTIVER, A SOUSA | 4 | 2018 |
Systematic optimization of prime editing for the efficient functional correction of CFTR F508del in human airway epithelial cells AA Sousa, C Hemez, L Lei, S Traore, K Kulhankova, GA Newby, ... Nature biomedical engineering, 1-15, 2024 | | 2024 |
Enhancement and Application of Prime Editing to Correct Pathogenic Mutations In Vitro and In Vivo AA Sousa | | 2024 |
Development of a Prime Editing Strategy to Treat Mutations in the Crumbs Homologue 1 (CRB1) Gene BL Costa, AA Sousa, YT Tsai, Y Li, IH Maumenee, DR Liu, SH Tsang, ... Investigative Ophthalmology & Visual Science 64 (8), 3862-3862, 2023 | | 2023 |
Development of a Prime Editing Strategy to Treat Mutations in the Crumbs Homologue 1 (CRB1) Gene BL Da Costa, AA Sousa, YT Tsai, Y Li, IH Maumenee, DR Liu, SH Tsang, ... MOLECULAR THERAPY 30 (4), 260-261, 2022 | | 2022 |
Variants of CPF1 (CAS12a) With Altered PAM Specificity JK Joung, B Kleinstiver, A Sousa US Patent App. 17/244,738, 2021 | | 2021 |
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