The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex Y Yokota, WY Kim, Y Chen, X Wang, A Stanco, Y Komuro, W Snider, ... Neuron 61 (1), 42-56, 2009 | 142 | 2009 |
Pten mutations alter brain growth trajectory and allocation of cell types through elevated β-catenin signaling Y Chen, WC Huang, J Séjourné, AE Clipperton-Allen, DT Page Journal of Neuroscience 35 (28), 10252-10267, 2015 | 107 | 2015 |
Hyperconnectivity of prefrontal cortex to amygdala projections in a mouse model of macrocephaly/autism syndrome WC Huang, Y Chen, DT Page Nature Communications 7, 13421, 2016 | 106 | 2016 |
Aggregation of the nucleic acid–binding protein TDP-43 occurs via distinct routes that are coordinated with stress granule formation Y Chen, TJ Cohen Journal of Biological Chemistry, jbc. RA118. 006351, 2019 | 95 | 2019 |
An HDAC6-dependent surveillance mechanism suppresses tau-mediated neurodegeneration and cognitive decline H Trzeciakiewicz, D Ajit, JH Tseng, Y Chen, A Ajit, Z Tabassum, ... Nature Communications 11 (1), 1-18, 2020 | 71 | 2020 |
Nucleocytoplasmic Shuttling of Receptor-interacting Protein 3 (RIP3) Y Yang, J Ma, Y Chen, M Wu Journal of Biological Chemistry 279 (37), 38820-38829, 2004 | 67 | 2004 |
Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease S Swarnkar, Y Chen, WM Pryor, N Shahani, DT Page, S Subramaniam Neurobiology of disease 82, 66-77, 2015 | 48 | 2015 |
Adenomatous Polyposis Coli Regulates Axon Arborization and Cytoskeleton Organization via Its N-Terminus Y Chen, X Tian, WY Kim, WD Snider PloS one 6 (9), e24335, 2011 | 32 | 2011 |
E2F1 inhibits MDM2 expression in a p53-dependent manner X Tian, Y Chen, W Hu, M Wu Cellular signalling 23 (1), 193-200, 2011 | 23 | 2011 |
Autism‐relevant behaviors are minimally impacted by conditional deletion of Pten in oxytocinergic neurons AE Clipperton‐Allen, Y Chen, DT Page Autism Research 9 (12), 1248-1262, 2016 | 19 | 2016 |
Tau seeds are subject to aberrant modifications resulting in distinct signatures JH Tseng, A Ajit, Z Tabassum, N Patel, X Tian, Y Chen, AW Prevatte, ... Cell Reports 35 (4), 109037, 2021 | 18 | 2021 |
A unique tau conformation generated by an acetylation-mimic substitution modulates P301S-dependent tau pathology and hyperphosphorylation D Ajit, H Trzeciakiewicz, JH Tseng, CM Wander, Y Chen, A Ajit, DP King, ... Journal of Biological Chemistry, jbc. RA119. 009674, 2019 | 14 | 2019 |
Homologous Recombination and Translesion DNA Synthesis Play Critical Roles on Tolerating DNA Damage Caused by Trace Levels of Hexavalent Chromium X Tian, K Patel, JR Ridpath, Y Chen, YH Zhou, D Neo, J Clement, ... PloS one 11 (12), e0167503, 2016 | 14 | 2016 |
Genomic and Proteomic Mechanisms and Models in Toxicity and Safety Evaluation of Nutraceuticals BM Kadakkuzha, X Liu, S Swarnkar, Y Chen Nutraceuticals: Efficacy, Safety and Toxicity, 227-237, 2016 | 10 | 2016 |
RNA-binding deficient TDP-43 drives cognitive decline in a mouse model of TDP-43 proteinopathy J Necarsulmer, J Simon, B Evangelista, Y Chen, X Tian, S Nafees, ... eLife 12, 2023 | 9 | 2023 |
Genetic Suppression of mTOR Rescues Synaptic and Social Behavioral Abnormalities in a Mouse Model of Pten Haploinsufficiency WC Huang, Y Chen, DT Page Autism Research, 2019 | 5 | 2019 |
Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity CK Opland, MR Bryan, B Harris, J McGillion-Moore, X Tian, Y Chen, ... Iscience 26 (6), 2023 | 3 | 2023 |
Identification of a reciprocal negative feedback loop between tau-modifying proteins MARK2 kinase and CBP acetyltransferase Z Tabassum, JH Tseng, C Isemann, X Tian, Y Chen, LE Herring, ... Journal of Biological Chemistry 298 (6), 2022 | 2 | 2022 |
Recent Advances in Alzheimer's Drug Discovery Research SVP Xin-An Liu, Brati Das, Youjun Chen, Zuxin Chen, Yosef Avchalumov, Xu Tian Frontiers in Clinical Drug Research-Alzheimer Disorders: Volume 7 7, 2018 | 1* | 2018 |
A Distinct Tau Code Controlled by HDAC6 is Linked to Tau Pathogenesis and the Neuronal Stress Response JH Tseng, A Ajit, Z Tabassum, N Patel, X Tian, Y Chen, AW Prevatte, ... Available at SSRN 3618575, 2020 | | 2020 |