| Neuronal replacement from endogenous precursors in the adult brain after stroke A Arvidsson, T Collin, D Kirik, Z Kokaia, O Lindvall Nature medicine 8 (9), 963-970, 2002 | 3636 | 2002 |
| Parkinson-like neurodegeneration induced by targeted overexpression of α-synuclein in the nigrostriatal system D Kirik, C Rosenblad, C Burger, C Lundberg, TE Johansen, N Muzyczka, ... Journal of Neuroscience 22 (7), 2780-2791, 2002 | 901 | 2002 |
| Characterization of behavioral and neurodegenerative changes following partial lesions of the nigrostriatal dopamine system induced by intrastriatal 6-hydroxydopamine in the rat D Kirik, C Rosenblad, A Björklund Experimental neurology 152 (2), 259-277, 1998 | 809 | 1998 |
| Pharmacological validation of behavioural measures of akinesia and dyskinesia in a rat model of Parkinson's disease M Lundblad, M Andersson, C Winkler, D Kirik, N Wierup, MA Cenci European Journal of Neuroscience 15 (1), 120-132, 2002 | 781 | 2002 |
| Dopamine released from 5-HT terminals is the cause of l-DOPA-induced dyskinesia in parkinsonian rats M Carta, T Carlsson, D Kirik, A Björklund Brain 130 (7), 1819-1833, 2007 | 720 | 2007 |
| Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned … D Kirik, C Rosenblad, A Björklund, RJ Mandel Journal of Neuroscience 20 (12), 4686-4700, 2000 | 491 | 2000 |
| Nigrostriatal α-synucleinopathy induced by viral vector-mediated overexpression of human α-synuclein: a new primate model of Parkinson's disease D Kirik, LE Annett, C Burger, N Muzyczka, RJ Mandel, A Björklund Proceedings of the National Academy of Sciences 100 (5), 2884-2889, 2003 | 489 | 2003 |
| L-DOPA-induced dyskinesia in the intrastriatal 6-hydroxydopamine model of parkinson's disease: relation to motor and cellular parameters of nigrostriatal function C Winkler, D Kirik, A Björklund, MA Cenci Neurobiology of disease 10 (2), 165-186, 2002 | 482 | 2002 |
| Towards a neuroprotective gene therapy for Parkinson’s disease: use of adenovirus, AAV and lentivirus vectors for gene transfer of GDNF to the nigrostriatal system in the rat … A Björklund, D Kirik, C Rosenblad, B Georgievska, C Lundberg, ... Brain research 886 (1-2), 82-98, 2000 | 432 | 2000 |
| A general chemical method to regulate protein stability in the mammalian central nervous system M Iwamoto, T Björklund, C Lundberg, D Kirik, TJ Wandless Chemistry & biology 17 (9), 981-988, 2010 | 430 | 2010 |
| Neurturin exerts potent actions on survival and function of midbrain dopaminergic neurons BA Horger, MC Nishimura, MP Armanini, LC Wang, KT Poulsen, ... Journal of Neuroscience 18 (13), 4929-4937, 1998 | 411 | 1998 |
| Localized striatal delivery of GDNF as a treatment for Parkinson disease D Kirik, B Georgievska, A Björklund Nature neuroscience 7 (2), 105-110, 2004 | 343 | 2004 |
| Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease A Björklund, C Rosenblad, C Winkler, D Kirik Neurobiology of disease 4 (3-4), 186-200, 1997 | 325 | 1997 |
| Cell transplantation in Parkinson's disease: how can we make it work? C Winkler, D Kirik, A Björklund Trends in neurosciences 28 (2), 86-92, 2005 | 321 | 2005 |
| Hippocampal Lewy pathology and cholinergic dysfunction are associated with dementia in Parkinson’s disease H Hall, S Reyes, N Landeck, C Bye, G Leanza, K Double, L Thompson, ... Brain 137 (9), 2493-2508, 2014 | 303 | 2014 |
| Combined 5-HT1A and 5-HT1B receptor agonists for the treatment of l-DOPA-induced dyskinesia A Munoz, Q Li, F Gardoni, E Marcello, C Qin, T Carlsson, D Kirik, ... Brain 131 (12), 3380-3394, 2008 | 290 | 2008 |
| Identification of dopaminergic neurons of nigral and ventral tegmental area subtypes in grafts of fetal ventral mesencephalon based on cell morphology, protein expression, and … L Thompson, P Barraud, E Andersson, D Kirik, A Björklund Journal of Neuroscience 25 (27), 6467-6477, 2005 | 288 | 2005 |
| Protection and regeneration of nigral dopaminergic neurons by neurturin or GDNF in a partial lesion model of Parkinson's disease after administration into the striatum or the … C Rosenblad, D Kirik, B Devaux, B Moffat, HS Phillips, A Björklund European Journal of Neuroscience 11 (5), 1554-1566, 1999 | 284 | 1999 |
| α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease I Lastres-Becker, A Ulusoy, NG Innamorato, G Sahin, A Rábano, D Kirik, ... Human molecular genetics 21 (14), 3173-3192, 2012 | 281 | 2012 |
| Microglia acquire distinct activation profiles depending on the degree of α-synuclein neuropathology in a rAAV based model of Parkinson's disease V Sanchez-Guajardo, F Febbraro, D Kirik, M Romero-Ramos PloS one 5 (1), e8784, 2010 | 274 | 2010 |
